Fort Myers, FL to Florence, SC bus

Fri, Dec 19
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
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Journey information

Overview: Bus from Fort Myers, FL to Florence, SC

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Take a bus from Fort Myers, FL to Florence, SC and enjoy the approximately 537 miles (865 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 03:18, the last at 19:05.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
537 miles (865 km)
First bus
03:18
Last bus
19:05
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Fort Myers, FL to Florence, SC

Find answers to the most common questions about traveling from Fort Myers, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
The first bus from Fort Myers, FL to Florence, SC leaves at 3: 18AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Fort Myers, FL to Florence, SC leaves at 5: 57PM.
A day trip to Florence, SC from Fort Myers, FL is worth doing with a journey time of min each way. Check with Omio app   the best way to travel.
No, the bus from Fort Myers, FL to Florence, SC has no accessibility options.
No, there are no bathrooms on board the bus from Fort Myers, FL to Florence, SC.
No, bikes are not allowed on board the bus from Fort Myers, FL to Florence, SC.

To find the cheapest bus tickets for your trip from Fort Myers, FL to Florence, SC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Fort Myers, FL to Florence, SC.
    No, luggage for the bus from Fort Myers, FL to Florence, SC needs to be booked in addition.
    No, there are no additional luggage options for the bus from Fort Myers, FL to Florence, SC.
    Unfortunately, pets are not allowed on the bus from Fort Myers, FL to Florence, SC.
    No, there are no USB plugs on board the bus from Fort Myers, FL to Florence, SC.
    No, there is no WiFi on board the bus from Fort Myers, FL to Florence, SC.

    popular bus stations

    Popular bus stations from Fort Myers, FL to Florence, SC

    Fort Myers
    Florence
    The major bus station for departures in Fort Myers is Fort Myers, Rosa Parks Transit Center. Find all the information you need to know about services, amenities and connections at Fort Myers, Rosa Parks Transit Center for your trip from Fort Myers to Florence.
    Fort Myers, Rosa Parks Transit Center
    information

    More options for your journey from Fort Myers, FL to Florence, SC

    Here are some other resources that might have the information you need

    Tickets and more information for coaches to Fort Myers, FL
    Tickets and more information for coaches to Florence, SC

    Most popular buses to and from Florence, SC and Fort Myers, FL

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    HomeBusesBuses in USABus tickets to Florence, SCFort Myers, FL to Florence, SC bus

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