- Must visit
Uffizi Galleries
Florence’s most famous art museum, home to Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Cheapest price
$25
Average price
$25
Fastest journey
2 h 15 m
Average duration
2 h 15 m
Buses per day
1
Distance
151 km
The best way to find a cheap bus ticket from Charlotte, NC to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to Florence, SC will cost around $25 if you buy it on the day, but the cheapest tickets can be found for only $25.
Of the 1 buses that leave Charlotte, NC for Florence, SC on Thu, May 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 151 km distance in an average of 2 h 15 m but if you time it right, some buses will get you there in just 2 h 15 m .
On Thu, May 28 the slowest buses will take 2 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Charlotte, NC to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a bus which can get you there in 2h 15m. The ticket price range depends on the travel mode: a bus costs an average of $22, and a train costs an average of $75.
Distance: 93 miles (151 km)
Most popular Bus | Train | Driving |
|---|---|---|
$37 Average price Cheapest | $100 Average price | $21 Average price (fuel + tolls) |
2h 45m Average total duration Fastest 2h 15m Onboard + 30m Additional time* | 13h 43m Average total duration 13h 13m Onboard + 30m Additional time* | 2h 16m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charlotte, NC to Florence, SC:
A bus is $62 (€50) less than a train for this route with tickets for a train from Charlotte, NC to Florence, SC costing on average $100 (€81).
Other travel options to Florence, SC take longer:
Train takes on average 13h 13m.
You'll arrive about 1m sooner (2h 15m by bus vs 2h 16m by car). Tickets start at around $37 (€30) compared to roughly $21 (€17) in fuel and tolls — a bit more, but you're getting time back, skipping traffic and parking, and you can work or rest on board.
Direct coaches are operated by FlixBus.
Driving makes more sense if you're travelling as a group (where fuel splits across several people), want flexibility on timing, or plan to stop en route.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15PM | Arrival Time 03:45PM | Duration 2h30 | Departure days Mon, Tue, Wed, Fri | Cheapest price $24 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 07:30PM | Duration 2h15 | Departure days Thu, Sat, Sun | Cheapest price $25 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 08:30PM | Duration 2h15 | Departure days Sat | Cheapest price $29 |
The table below shows live departures for Charlotte, NC to Florence, SC buses for today, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 1:15 PM Charlotte, W 4th St (Greyhound Bus Station) | 2h30 | 3:45 PM Florence, S Irby St (Greyhound Bus Stop), SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Charlotte, NC to Florence, SC run on average 1 times per day, taking around 2h 15m. Cheap bus tickets for this journey start at $22 (€18) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 21:30. The fastest bus covers the 93 miles (151 km) distance in 2h 15m.
Distance 93 miles (151 km) |
Average bus duration 2h 15m |
Cheapest ticket price $22 (€18) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 2h 15m |
First bus 12:05 AM |
Last bus 9:30 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
Florence’s most famous art museum, home to Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Best known for Michelangelo’s David, this compact museum is one of the city’s essential art stops. Advance booking is commonly recommended.
A vast former Medici palace with major collections including the Palatine Gallery and royal apartments. Worth visiting for both art and historic interiors.
Florence’s monumental heart, surrounded by the cathedral, baptistery, and bell tower. Busy, photogenic, and essential for first-time visitors.
Historic civic square lined with sculpture and monumental buildings, including Palazzo Vecchio. One of the city’s most important public spaces.
The classic panoramic viewpoint over Florence, especially popular at sunset and widely shared on social media. A top spot for skyline photos.
A Pee Dee region classic of rice, chicken, sausage, and spices cooked together until rich and hearty. It is one of the best-known traditional dishes around Florence and nearby communities.
Creamy grits topped with shrimp, often with bacon or a savory gravy. This Lowcountry staple is widely associated with coastal South Carolina cuisine and commonly enjoyed in Florence.
Slices of unripe tomato breaded and fried until crisp, often served with remoulade. A classic Southern starter found across South Carolina.
Upscale, long-established restaurant in downtown Florence known for refined Southern cuisine, steaks, seafood, and a polished atmosphere.
Popular casual barbecue spot known for smoked meats, Southern sides, and a lively downtown setting.
Well-known Florence restaurant serving Southern and American dishes in a stylish but approachable setting.
Prices are moderate by U.S. standards. Casual dining is affordable, while nicer restaurants and hotels cost more.
Tip 18-20% at full-service restaurants. Tip USD 1-2 per drink at bars, round up or tip 10% for taxis, and tip hotel staff for service.
Find answers to the most common questions about traveling from Charlotte, NC to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

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