- Must visit
Uffizi Galleries
Florence’s premier art museum, famed for Botticelli, Leonardo, and Michelangelo. One of Italy’s essential Renaissance collections and a top priority for first-time visitors.
We are not able to find a bus between these two places.
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Omio recommends booking the bus as it is the most popular option from Charlotte, NC to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a bus which can get you there in 2h 15m. The ticket price range depends on the travel mode: a bus costs an average of $22, and a train costs an average of $74.
Distance: 93 miles (151 km)
Most popular Bus | Train | Driving |
|---|---|---|
$37 Average price Cheapest | $98 Average price | $21 Average price (fuel + tolls) |
2h 45m Average total duration Fastest 2h 15m Onboard + 30m Additional time* | 13h 43m Average total duration 13h 13m Onboard + 30m Additional time* | 2h 16m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charlotte, NC to Florence, SC:
A bus is $61 (€50) less than a train for this route with tickets for a train from Charlotte, NC to Florence, SC costing on average $98 (€81).
Other travel options to Florence, SC take longer:
Train takes on average 13h 13m.
You'll arrive about 1m sooner (2h 15m by bus vs 2h 16m by car). Tickets start at around $37 (€30) compared to roughly $21 (€17) in fuel and tolls — a bit more, but you're getting time back, skipping traffic and parking, and you can work or rest on board.
Direct coaches are operated by FlixBus.
Driving makes more sense if you're travelling as a group (where fuel splits across several people), want flexibility on timing, or plan to stop en route.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:25AM | Arrival Time 10:45AM | Duration 8h20 | Departure days Sat | Cheapest price $79 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 07:30PM | Duration 2h15 | Departure days Mon, Thu, Fri, Sat | Cheapest price $24 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 08:30PM | Duration 2h15 | Departure days Mon, Fri, Sat | Cheapest price $26 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 05:45AM | Duration 7h55 | Departure days Tue, Wed, Sun | Cheapest price $57 |
The table below shows live departures for Charlotte, NC to Florence, SC buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:15 PM Charlotte, NC | 2h15 | 7:30 PM Florence, SC | 0 transfersDirect | |
![]() | 6:15 PM Charlotte, NC | 2h15 | 8:30 PM Florence, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Charlotte, NC to Florence, SC run on average 1 times per day, taking around 2h 15m. Cheap bus tickets for this journey start at $22 (€18) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 21:30. The fastest bus covers the 93 miles (151 km) distance in 2h 15m.
Distance 93 miles (151 km) |
Average bus duration 2h 15m |
Cheapest ticket price $22 (€18) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 2h 15m |
First bus 12:05 AM |
Last bus 9:30 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
Florence’s premier art museum, famed for Botticelli, Leonardo, and Michelangelo. One of Italy’s essential Renaissance collections and a top priority for first-time visitors.
Best known for Michelangelo’s David, this compact museum is one of Florence’s most iconic cultural stops and often requires advance booking.
A vast palace museum complex with royal apartments, galleries, and decorative arts. Ideal for visitors wanting art and Medici history in one place.
The monumental heart of Florence, surrounded by the cathedral, baptistery, and bell tower. Constantly lively and central to most visits.
Florence’s grand civic square, filled with historic atmosphere, sculpture, and major landmarks including Palazzo Vecchio.
The city’s most famous viewpoint, especially popular at sunset and on social media for sweeping panoramas over Florence.
Slow-smoked pork, usually chopped or pulled and served with a tangy sauce. It is a staple across the Pee Dee region and one of the most recognizable local comfort foods.
Cornmeal-coated catfish fried until crisp, often served with hush puppies and slaw. It reflects the river and Southern fish-fry traditions common in the area.
Creamy grits topped with seasoned shrimp, a Lowcountry and coastal Carolinas classic also widely enjoyed in Florence. It blends Southern farmhouse cooking with seafood traditions.
An established upscale restaurant in Florence known for steaks, seafood, and polished Southern-American dining in an elegant setting.
A popular casual barbecue spot known for smoked meats, Southern sides, and a lively downtown atmosphere.
A long-running local favorite serving Southern and American comfort food in a distinctive, character-filled setting.
Prices are moderate by U.S. standards. Casual dining is affordable, while upscale restaurants and hotels cost more.
Tip 18-20% in restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 1-5 depending on service.
Find answers to the most common questions about traveling from Charlotte, NC to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Charlotte, NC to Florence, SC buses use the Charlotte, W 4th St (Greyhound Bus Station) to Florence, S Irby St (Greyhound Bus Stop) station pair. Use this guide to compare Charlotte, NC and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need