- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Cheapest price on Oct 10
$56
Average ticket price on Oct 10
$56
Fastest journey on Oct 10
7 h 55 m
Average journey duration on Oct 10
7 h 55 m
Buses on Oct 10
1
Distance
151 km
The best way to find a cheap bus ticket from Charlotte, NC to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to Florence, SC will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $56.
It's difficult to get from Charlotte, NC to Florence, SC without transferring at least once.
FlixBus+
FlixBus+
Buses from Charlotte, NC to Florence, SC run on average 1 times per day, taking around 4h 42m. Cheap bus tickets for this journey start at $22 if you book in advance.
The earliest bus runs at 00:05, the last at 21:30. The fastest bus covers the 93 miles (151 km) distance in 2h 15m.
Distance 93 miles (151 km) |
Average bus duration 4h 42m |
Cheapest ticket price $22 |
Buses per day 1 |
Fastest bus 2h 15m |
First bus 12:05 AM |
Last bus 9:30 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:15PM | Arrival Time 07:30PM | Duration 2h15 | Departure days Mon, Tue | Cheapest price $28 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 08:30PM | Duration 2h15 | Departure days Mon, Tue | Cheapest price $29 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 05:45AM | Duration 7h55 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $50 |
The table below shows live departures for Charlotte, NC to Florence, SC buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 9:50 PM Charlotte, W 4th St (Greyhound Bus Station) | 7h55 | 5:45 AM Florence, W Lucas St (TA Gas Station), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
Find answers to the most common questions about traveling from Charlotte, NC to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Charlotte, NC to Florence, SC buses use the Charlotte, W 4th St (Greyhound Bus Station) to Florence, W Lucas St (TA Gas Station) station pair, with some services arriving at Florence, S Irby St (Greyhound Bus Stop). Use this guide to compare Charlotte, NC and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charlotte, W 4th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Charlotte, W 4th St (Greyhound Bus Station). ATMs are available at Charlotte, W 4th St (Greyhound Bus Station).
Ticket office support is available at Charlotte, W 4th St (Greyhound Bus Station).
Available at Charlotte, W 4th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charlotte, W 4th St (Greyhound Bus Station): The station is wheelchair accessible.
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food and snacks available at the gas station.
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
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