- Must visit
The Neon Museum
Outdoor museum preserving iconic Las Vegas signs, with guided tours through the Neon Boneyard. A signature city experience blending design, history, and photography.
Omio recommends booking the bus as it is the most popular option from Fort Myers, FL to Las Vegas, NV among Omio's users. If you are prioritising price take the bus with prices starting from $168. For those with little time consider booking a flight which can get you there in 12h 28m. The ticket price range depends on the travel mode: a bus costs an average of $168, and a train costs an average of $565.
Distance: 2059 miles (3315 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$174 Average price Cheapest | $565 Average price | $240 Average price | $494 Average price (fuel + tolls) |
76h 8m Average total duration 75h 38m Onboard + 30m Additional time* | 95h 20m Average total duration 94h 50m Onboard + 30m Additional time* | 15h 28m Average total duration Fastest 12h 28m Onboard + 3h 0m Additional time* | 35h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Fort Myers, FL to Las Vegas, NV:
A bus is $66 (€53) less than a flight for this route with tickets for a flight from Fort Myers, FL to Las Vegas, NV costing on average $240 (€193).
A bus is $392 (€315) less than a train for this route with tickets for a train from Fort Myers, FL to Las Vegas, NV costing on average $565 (€455).
Other travel options to Las Vegas, NV take longer:
Bus takes on average 75h 38m.
Train takes on average 94h 50m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:45PM | Arrival Time 07:40PM | Duration 76h55 | Departure days Fri | Cheapest price $168 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 12:50AM | Duration 74h20 | Departure days Thu | Cheapest price $180 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Fort Myers, FL to Las Vegas, NV run on average 7 times per day, taking around 75h 38m. Cheap bus tickets for this journey start at $168 (€135) if you book in advance.
The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 2059 miles (3315 km) distance in 74h 20m.
Distance 2059 miles (3315 km) |
Average bus duration 75h 38m |
Cheapest ticket price $168 (€135) |
Buses per day 7 |
Fastest bus 74h 20m |
First bus 12:15 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jan - Mar |
Best time to book 7 days |
Discover the best of Las Vegas — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Las Vegas trip today.
Outdoor museum preserving iconic Las Vegas signs, with guided tours through the Neon Boneyard. A signature city experience blending design, history, and photography.
Officially the National Museum of Organized Crime and Law Enforcement, this interactive museum explores crime history, policing, and Prohibition-era Las Vegas.
Small but respected gallery inside Bellagio presenting rotating exhibitions. Good for visitors wanting a compact fine-art stop on the Strip.
The city's best-known corridor of major resorts, shows, landmarks, and nonstop pedestrian activity. Essential for first-time visitors and night views.
Pedestrian entertainment district in Downtown Las Vegas with a giant LED canopy, live music, and historic casino frontage. One of the city's signature areas.
Scenic loop west of the city featuring desert landscapes, overlooks, and trail access. A top outdoor escape for views, photography, and short walks.
A classic Las Vegas casino snack, usually served chilled with a tangy cocktail sauce. It became iconic on the Strip through old-school steakhouses and casino coffee shops.
A traditional Las Vegas steakhouse favorite, slow-roasted and carved thick. It reflects the city’s long-running supper-club and casino dining culture.
A hearty casino cafe staple often associated with late-night and 24-hour dining in Las Vegas. It is simple, filling, and strongly tied to classic gambler culture.
Popular Arts District restaurant focused on seasonal Italian food, house-made pasta, and a lively neighborhood atmosphere.
Historic old-school steakhouse known for prime rib, steaks, and classic Vegas atmosphere with red-leather booths and vintage charm.
Widely known restaurant specializing in Northern Thai cuisine, celebrated for deeply flavored regional dishes and a long-established local reputation.
Food and drinks can be pricey on the Strip, but off-Strip dining and budget hotels offer better value.
Tip 15-20% in restaurants and bars; USD 1-2 per drink. Taxis 10-15%. Hotel staff USD 2-5. Tips are expected.
Find answers to the most common questions about traveling from Fort Myers, FL to Las Vegas, NV by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Las Vegas, NV, this guide helps you travel smarter and with confidence.

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