The cheapest and fastest buses from Baltimore, MD to Florence, SC
Cheapest price
$207
Average price
$207
Fastest journey
10 h 55 m
Average duration
10 h 55 m
Buses per day
1
Distance
632 km
The best way to find a cheap bus ticket from Baltimore, MD to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Baltimore, MD to Florence, SC will cost around $207 if you buy it on the day, but the cheapest tickets can be found for only $207.
It's difficult to get from Baltimore, MD to Florence, SC without transferring at least once.


Travel Information
Compare train and bus for Baltimore, MD to Florence, SC
Omio recommends booking the train as it is the most popular option from Baltimore, MD to Florence, SC among Omio's users. If you are prioritising price take the train with prices starting from €107. For those with little time consider booking a bus which can get you there in 8h 50m. The ticket price range depends on the travel mode: a train costs an average of €107, and a bus costs an average of €170.
Distance: 392 miles (632 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€170 Average price | €170 Average price Cheapest |
9h 20m Average total duration Fastest 8h 50m Onboard + 30m Additional time* | 9h 36m Average total duration 9h 6m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Compare prices and tickets Baltimore, MD to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
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Journey information
Overview: Bus from Baltimore, MD to Florence, SC
Distance 392 miles (632 km) |
Average bus duration 8h 50m |
Cheapest ticket price $208 (€170) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 10h 55m |
First bus 00:05 |
Last bus 23:45 |
Bus providers: FlixBus, Greyhound from Baltimore, MD to Florence, SCYou can travel by bus between Baltimore, MD to Florence, SC with FlixBus, Greyhound for as low as $131 (€107). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Baltimore, MD to Florence, SC

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Baltimore, MD to Florence, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Baltimore, MD to Florence, SC
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