- Must visit
Uffizi Galleries
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Cheapest price
$96
Average price
$126
Fastest journey
7 h 55 m
Average duration
9 h 18 m
Buses per day
3
Distance
576 km
The best way to find a cheap bus ticket from Washington, DC to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Washington, DC to Florence, SC will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $96.
Of the 3 buses that leave Washington, DC for Florence, SC on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 576 km distance in an average of 9 h 18 m but if you time it right, some buses will get you there in just 7 h 55 m .
On Sat, Jun 20 the slowest buses will take 12 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus
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FlixBus
· Omio recommends booking the train as it is the most popular option from Washington, DC to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a train which can get you there in 7h 51m. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $74.
Distance: 357 miles (576 km)
| Bus | Most popular Train |
|---|---|
$83 Average price Cheapest | $129 Average price |
8h 26m Average total duration 7h 56m Onboard + 30m Additional time* | 8h 21m Average total duration Fastest 7h 51m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
This is compared to other travel options from Washington, DC to Florence, SC:
A bus is $45 (€37) less than a train for this route with tickets for a train from Washington, DC to Florence, SC costing on average $129 (€105).
Other travel options to Florence, SC take longer:
Bus takes on average 7h 56m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:45AM | Arrival Time 09:45AM | Duration 8h00 | Departure days Fri | Cheapest price $94 |
Operator FlixBus | Departure Time 02:45AM | Arrival Time 10:45AM | Duration 8h00 | Departure days Sat | Cheapest price $83 |
Operator Greyhound | Departure Time 03:10AM | Arrival Time 04:45PM | Duration 13h35 | Departure days Fri, Sat | Cheapest price $63 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 11:45AM | Duration 7h55 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 05:45AM | Duration 8h00 | Departure days Tue, Wed, Sat, Sun | Cheapest price $90 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 11:45AM | Duration 12h00 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $67 |
The table below shows live departures for Washington, DC to Florence, SC buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 3:50 AM Washington, Columbus Circle, Union Station | 7h55 | 11:45 AM Florence, S Irby St (Greyhound Bus Stop), SC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Washington, DC to Florence, SC run on average 2 times per day, taking around 7h 56m. Cheap bus tickets for this journey start at $62 (€51) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 22:10. The fastest bus covers the 357 miles (576 km) distance in 8h 0m.
Distance 357 miles (576 km) |
Average bus duration 7h 56m |
Cheapest ticket price $62 (€51) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 8h 0m |
First bus 12:05 AM |
Last bus 10:10 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 2 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Best known for Michelangelo’s David, this compact museum is one of Florence’s essential stops. Advance booking is commonly recommended because queues can be long.
Large palace museum complex with royal apartments, paintings, and design collections. Worth visiting for its scale, courtly interiors, and links to Medici history.
The monumental heart of Florence, surrounded by the cathedral, dome, baptistery, and bell tower. Essential for first-time visitors and classic city views.
Historic square lined with civic architecture and open-air sculptures. One of Florence’s liveliest public spaces and a key stop on any walking route.
The city’s most famous viewpoint, especially popular at sunset for sweeping skyline photos. A social media favorite and classic Florence panorama.
Slow-smoked pork shoulder, usually chopped or pulled and served with a tangy Southern barbecue sauce. It is a staple across the Carolinas and common in Florence-area smokehouses.
Cornmeal-coated catfish fillets fried until crisp, often served with hush puppies and slaw. This is a classic Pee Dee and broader South Carolina comfort dish.
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a light sauce. A defining Lowcountry and South Carolina dish regularly found in Florence.
Established downtown barbecue spot specializing in smoked meats, Southern sides, and a casual local atmosphere.
Upscale, long-running Florence restaurant known for steaks, seafood, and polished Southern-American dining in an elegant setting.
Well-known casual seafood restaurant recognized for fried seafood platters, shrimp, fish, and regional comfort fare.
Costs are moderate for the U.S. Budget eats are easy to find, while hotels and fine dining can raise daily costs.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff USD 2-5 for helpful service.
Find answers to the most common questions about traveling from Washington, DC to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

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