The cheapest and fastest buses from Daytona Beach, FL to Florence, SC
Cheapest price
$80
Average price
$80
Fastest journey
18 h 30 m
Average duration
18 h 30 m
Buses per day
1
Distance
567 km
The best way to find a cheap bus ticket from Daytona Beach, FL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Daytona Beach, FL to Florence, SC will cost around $80 if you buy it on the day, but the cheapest tickets can be found for only $80.
It's difficult to get from Daytona Beach, FL to Florence, SC without transferring at least once.


Daytona Beach, FL to Florence, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:15AM | Arrival Time 01:25PM | Duration 8h10 | Departure days Sat | Cheapest price $102 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 01:25PM | Duration 7h25 | Departure days Sat | Cheapest price $144 |
Operator FlixBus | Departure Time 01:55PM | Arrival Time 12:05AM | Duration 10h10 | Departure days Sat | Cheapest price $144 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 12:05AM | Duration 7h15 | Departure days Sat | Cheapest price $106 |
Live departures
Daytona Beach, FL to Florence, SC bus times
The table below shows live departures for Daytona Beach, FL to Florence, SC buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:55 PM Daytona Beach, S Ridgewood Ave (Greyhound Bus Station), FL | 10h10 | 4:05 AM Florence, W Lucas St (TA Gas Station), SC | 1 transfer | |
FlixBus | 8:50 PM Daytona Beach, Cornerstone Blvd ("Tanger Outlets" parking lot), FL | 7h15 | 4:05 AM Florence, W Lucas St (TA Gas Station), SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Daytona Beach, FL to Florence, SC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Daytona Beach, FL to Florence, SC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Daytona Beach, FL to Florence, SC
Buses from Daytona Beach, FL to Florence, SC run on average 1 times per day, taking around 19h 55m. Cheap bus tickets for this journey start at $176 (€143) if you book in advance.
The earliest bus runs at 05:15, the last at 16:50. The fastest bus covers the 352 miles (567 km) distance in 19h 55m.
Distance 352 miles (567 km) |
Average bus duration 19h 55m |
Cheapest ticket price $176 (€143) |
Buses per day 1 |
Fastest bus 19h 55m |
First bus 05:15 |
Last bus 16:50 |
Bus providers: Greyhound from Daytona Beach, FL to Florence, SCYou can travel by bus between Daytona Beach, FL to Florence, SC with Greyhound for as low as $176 (€143). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Daytona Beach, FL to Florence, SC
Find answers to the most common questions about traveling from Daytona Beach, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Daytona Beach, FL to Florence, SC
Most popular bus connections from Daytona Beach, FL
More options for your journey from Daytona Beach, FL to Florence, SC
Here are some other resources that might have the information you need
