Boston, MA to Florence, SC bus with Greyhound

Wed, Feb 04
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Greyhound
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
1,000+ travel companies
Greyhound
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
1,000+ travel companies
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The cheapest and fastest buses from Boston, MA to Florence, SC

Showing times and prices for Feb 05

Cheapest price

$222

Average price

$222

Fastest journey

1 d 25 m

Average duration

1 d 25 m

Buses per day

1

Distance

1182 km

Cheap tickets

The best way to find a cheap bus ticket from Boston, MA to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Boston, MA to Florence, SC will cost around $222 if you buy it on the day, but the cheapest tickets can be found for only $222.

Fast buses

It's difficult to get from Boston, MA to Florence, SC without transferring at least 2 times.

Flixbus USA
02:00PM24h25
Boston, MA
02:25PMFlorence, SC
$2221One-way
2 transfers

Travel Information

Compare train and bus for Boston, MA to Florence, SC

Omio recommends booking the train as it is the most popular option from Boston, MA to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from €81. For those with little time consider booking a train which can get you there in 16h 1m. The ticket price range depends on the travel mode: a bus costs an average of €81, and a train costs an average of €114.

Distance: 734 miles (1182 km)

Compare bus with

Bus
Most popular
Train

€81

Average price

Cheapest

€219

Average price

18h 5m

Average total duration

17h 35m

Onboard

+

30m

Additional time*

16h 31m

Average total duration

Fastest

16h 1m

Onboard

+

30m

Additional time*

Greyhound

Most popular bus company

Amtrak

Most popular train company

Direct Options

Direct Options

Boston, MA to Florence, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
04:45PM
Arrival Time
11:45AM
Duration
19h00
Departure days
Tue
Cheapest price
$195
Operator
FlixBus
Departure Time
09:50PM
Arrival Time
05:45AM
Duration
31h55
Departure days
Tue
Cheapest price
$199

Compare prices and tickets Boston, MA to Florence, SC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Feb 05
Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
Mon
Feb 09
Tue
Feb 10
Wed
Feb 11

Why should you book Boston, MA to Florence, SC buses with Omio?

FlixBus as well as Greyhound offer buses services from Boston, MA to Florence, SC.
Omio is an official ticket reseller for all your travel options from Boston, MA to Florence, SC.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Boston, MA to Florence, SC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Boston, MA to Florence, SC.

Why book with Omio over Wanderu?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Boston, MA to Florence, SC.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Boston, MA to Florence, SC.

Journey information

Overview: Bus from Boston, MA to Florence, SC

USAUSA
USAUSA
Icon of bus

Buses from Boston, MA to Florence, SC run on average 2 times per day, taking around 17h 35m. Cheap bus tickets for this journey start at $102 (€81) if you book in advance.

The earliest bus runs at 00:05, the last at 20:55. The fastest bus covers the 734 miles (1182 km) distance in 19h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
734 miles (1182 km)
Average bus duration
17h 35m
Cheapest ticket price
$102 (€81)
Buses per day
2
Fastest bus
19h 5m
First bus
00:05
Last bus
20:55
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Boston, MA to Florence, SCYou can travel by bus between Boston, MA to Florence, SC with Greyhound, FlixBus for as low as $102 (€81). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
22h 25m
Cheapest Price
$222 (€176)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Boston, MA to Florence, SC

Find answers to the most common questions about traveling from Boston, MA to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Boston, MA to Florence, SC can start from as little as $102 (€81) when you book in advance. The average bus ticket price for Boston, MA to Florence, SC is $102 (€81) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Boston, MA to Florence, SC is 19h 5m to travel the 734 miles (1182 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Boston, MA to Florence, SC leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Boston, MA to Florence, SC leaves at 8:55 PM.
There are 2 buses a day from Boston, MA to Florence, SC which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Boston, MA to Florence, SC, you can count on Greyhound, FlixBus for the best way to get you to Florence, SC. You can also check all possible bus companies who offer a service between Boston, MA and Florence, SC and compare the amenities they offer before buying a bus ticket.
A trip to Florence, SC from Boston, MA is worth doing but not as a day trip with a journey time of 19h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Boston, MA to Florence, SC is April.
It's helpful to compare your options as there are 2 ways to travel between Boston, MA and Florence, SC including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Boston, MA to Florence, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Boston, MA to Florence, SC for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Boston, MA to Florence, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Boston, MA to Florence, SC.
Yes, the following luggage options are included when booking a bus ticket from Boston, MA to Florence, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Boston, MA to Florence, SC:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Boston, MA to Florence, SC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Boston, MA to Florence, SC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Boston, MA to Florence, SC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Boston, MA to Florence, SC with the following bus company: Greyhound, FlixBus.

popular bus stations

Popular bus stations from Boston, MA to Florence, SC

Boston
Florence
The major bus station for departures in Boston is Boston, Bus Terminal South Station. Find all the information you need to know about services, amenities and connections at Boston, Bus Terminal South Station for your trip from Boston to Florence.
Boston, Bus Terminal South Station
information

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