- Must visit
Florida Museum Of Natural History
The State Of Florida’s official natural history museum, known for fossil, biodiversity, and cultural exhibits. A top family-friendly stop at the University Of Florida.
Cheapest price
$86
Average price
$89
Fastest journey
5 h 5 m
Average duration
12 h 37 m
Buses per day
5
Distance
340 km
The best way to find a cheap bus ticket from Fort Myers, FL to Gainesville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Gainesville, FL will cost around $89 if you buy it on the day, but the cheapest tickets can be found for only $86.
Of the 5 buses that leave Fort Myers, FL for Gainesville, FL on Fri, Jul 10, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 10 the direct buses cover the 340 km distance in an average of 12 h 37 m but if you time it right, some buses will get you there in just 5 h 5 m .
On Fri, Jul 10 the slowest buses will take 17 h 4 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Fort Myers, FL to Gainesville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $92. For those with little time consider booking a bus which can get you there in 9h 5m. The ticket price range depends on the travel mode: a bus costs an average of $92, and a flight costs an average of $878.
Distance: 211 miles (340 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$98 Average price Cheapest | $878 Average price | $46 Average price (fuel + tolls) |
9h 35m Average total duration Fastest 9h 5m Onboard + 30m Additional time* | 13h 40m Average total duration 10h 40m Onboard + 3h 0m Additional time* | 3h 46m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Fort Myers, FL to Gainesville, FL:
A bus is $780 (€640) less than a flight for this route with tickets for a flight from Fort Myers, FL to Gainesville, FL costing on average $878 (€721).
Other travel options to Gainesville, FL take longer:
Flight takes on average 10h 40m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Pinkbus | Departure Time 11:55AM | Arrival Time 05:00PM | Duration 5h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $61 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 01:05AM | Duration 12h45 | Departure days Tue, Wed | Cheapest price $59 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 01:05AM | Duration 11h05 | Departure days Mon, Thu, Fri, Sat | Cheapest price $56 |
Operator Flixbus USA | Departure Time 06:20PM | Arrival Time 05:00PM | Duration 22h40 | Departure days Sun | Cheapest price $156 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 11:25AM | Duration 16h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 11:59AM | Duration 17h04 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $56 |
The table below shows live departures for Fort Myers, FL to Gainesville, FL buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ + FlixBus | 6:30 PM Fort Myers, Rosa Parks Transit Center | 16h55 | 11:25 AM Gainesville, Rosa Parks Transfer station | 2 transfers | |
FlixBus+![]() | 6:55 PM Fort Myers, Rosa Parks Transit Center | 12h55 | 7:50 AM Gainesville, NW 23rd St (North Walmart Supercenter), FL | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:55 PM Fort Myers, Rosa Parks Transit Center | 17h04 | 11:59 AM Gainesville, Rosa Parks Transfer station | 2 transfers | |
| Friday, July 10 | |||||
![]() | 11:55 AM Fort Myers, Old Luckett Drive, FL | 5h05 | 5:00 PM Gainesville, Gale Lemerand Dr (Commuter Lot Parking Garage), FL | 0 transfersDirect | |
FlixBus · FlixBus | 2:00 PM Fort Myers, Rosa Parks Transit Center | 11h05 | 1:05 AM Gainesville, Rosa Parks Transfer station | 1 transfer | |
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Fort Myers, FL to Gainesville, FL run on average 4 times per day, taking around 9h 5m. Cheap bus tickets for this journey start at $92 (€75) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 22:40. The fastest bus covers the 211 miles (340 km) distance in 5h 5m.
Distance 211 miles (340 km) |
Average bus duration 9h 5m |
Cheapest ticket price $92 (€75) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 5h 5m |
First bus 12:25 AM |
Last bus 10:40 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Discover the best of Gainesville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Gainesville trip today.
The State Of Florida’s official natural history museum, known for fossil, biodiversity, and cultural exhibits. A top family-friendly stop at the University Of Florida.
A major university art museum with African, Asian, modern, and contemporary collections. Strong exhibitions and a calm setting make it one of Gainesville’s best cultural visits.
Interactive museum focused on science, creativity, and invention, inspired by inventor Robert Cade. Popular with families and visitors seeking hands-on experiences.
One of Gainesville’s most popular public spaces, with walking paths, open lawns, water features, and frequent social media visibility.
Large preserve south of the city known for wildlife, prairie views, trails, and observation points. A signature outdoor experience near Gainesville.
Walkable campus area with historic buildings, green spaces, and major landmarks. Essential for first-time visitors to Gainesville.
A North Florida specialty, usually cut into bite-size pieces, breaded or grilled, and served with dipping sauce. It is a regional novelty tied to Florida’s wild game traditions.
Slow-smoked pork or brisket served with classic Southern sides such as baked beans, slaw, and cornbread. Barbecue is deeply rooted in North Florida’s local food culture.
Cornmeal-crusted catfish, usually fried and served with hush puppies or grits. It reflects the inland Southern cooking traditions common around Gainesville.
A highly regarded Gainesville institution famous for quirky decor, family-friendly charm, and well-loved pizza, salads, and casual local character.
An established upscale steakhouse known for wood-grilled steaks, seafood, and polished service. A strong choice for a refined dinner in Gainesville.
A popular, stylish restaurant in downtown Gainesville specializing in sushi, Japanese small plates, and sake in a modern social setting.
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and upscale meals can cost more on busy university weekends.
Tip 18-20% at restaurants with table service. Tip USD 1-2 per drink at bars, round up or add 10-15% for taxis, and tip delivery drivers about 10-20%.
Find answers to the most common questions about traveling from Fort Myers, FL to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.

Most Fort Myers, FL to Gainesville, FL buses use the Fort Myers, Rosa Parks Transit Center to Gainesville, Rosa Parks Transfer station station pair, with some services arriving at Gainesville, NW 23rd St (North Walmart Supercenter). Use this guide to compare Fort Myers, FL and Gainesville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need