- Must visit
Florida Museum of Natural History
The state’s official natural history museum, known for Florida fossils, biodiversity, and rotating family-friendly exhibits. A top cultural stop near the university.
Cheapest price
$107
Average price
$107
Fastest journey
5 h 5 m
Average duration
5 h 5 m
Buses per day
1
Distance
340 km
The best way to find a cheap bus ticket from Fort Myers, FL to Gainesville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Gainesville, FL will cost around $107 if you buy it on the day, but the cheapest tickets can be found for only $107.
Of the 1 buses that leave Fort Myers, FL for Gainesville, FL on Tue, May 26, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 26 the direct buses cover the 340 km distance in an average of 5 h 5 m but if you time it right, some buses will get you there in just 5 h 5 m .
On Tue, May 26 the slowest buses will take 5 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Fort Myers, FL to Gainesville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $93. For those with little time consider booking a bus which can get you there in 9h 5m. The ticket price range depends on the travel mode: a bus costs an average of $93, and a flight costs an average of $894.
Distance: 211 miles (340 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$100 Average price Cheapest | $894 Average price | $47 Average price (fuel + tolls) |
9h 35m Average total duration Fastest 9h 5m Onboard + 30m Additional time* | 13h 40m Average total duration 10h 40m Onboard + 3h 0m Additional time* | 3h 46m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Fort Myers, FL to Gainesville, FL:
A bus is $794 (€640) less than a flight for this route with tickets for a flight from Fort Myers, FL to Gainesville, FL costing on average $894 (€721).
Other travel options to Gainesville, FL take longer:
Flight takes on average 10h 40m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Pinkbus | Departure Time 03:55PM | Arrival Time 09:00PM | Duration 5h05 | Departure days Tue | Cheapest price $107 |
Operator Pinkbus | Departure Time 04:55PM | Arrival Time 10:00PM | Duration 5h05 | Departure days Wed | Cheapest price $93 |
Operator Flixbus USA | Departure Time 06:20PM | Arrival Time 05:00PM | Duration 22h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price $159 |
The table below shows live departures for Fort Myers, FL to Gainesville, FL buses for tomorrow, Tuesday, May 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:55 PM Fort Myers, FL | 5h05 | 9:00 PM Gainesville, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Fort Myers, FL to Gainesville, FL run on average 4 times per day, taking around 9h 5m. Cheap bus tickets for this journey start at $93 (€75) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 22:40. The fastest bus covers the 211 miles (340 km) distance in 5h 5m.
Distance 211 miles (340 km) |
Average bus duration 9h 5m |
Cheapest ticket price $93 (€75) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 5h 5m |
First bus 12:25 AM |
Last bus 10:40 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Discover the best of Gainesville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Gainesville trip today.
The state’s official natural history museum, known for Florida fossils, biodiversity, and rotating family-friendly exhibits. A top cultural stop near the university.
A major university art museum with strong Asian, African, modern, and contemporary collections. Well regarded for its architecture and high-quality temporary exhibitions.
Popular UF art museum featuring global collections and thoughtful curated shows. A local favorite for a quiet cultural visit near other campus attractions.
One of Gainesville’s most popular public spaces, with walking paths, open lawns, play areas, and lake views. Very popular with locals and on social media.
Expansive prairie landscape south of the city known for wild horses, bison sightings, boardwalks, and sweeping views. A signature natural experience near Gainesville.
A lush sinkhole park with a descending boardwalk into a miniature rainforest. One of the area’s most distinctive natural attractions.
A North Florida specialty usually cut into nuggets or strips and fried or blackened. It is closely associated with Florida’s hunting and game-meat traditions.
A classic regional dish of cornmeal-coated catfish, often served with hush puppies, slaw, and grits. It reflects the inland Southern cooking found around North Florida.
Creamy grits topped with shrimp, often with bacon, gravy, or a spicy sauce. While broader Southern in origin, it is a staple on many Gainesville-area menus.
An iconic local pizzeria loved for quirky decor, creative atmosphere, and reliable pizzas and salads. One of Gainesville’s most recognizable casual dining spots.
An established upscale steakhouse known for wood-grilled meats, seafood, and polished service. Popular for date nights and celebratory dinners.
A well-known downtown restaurant serving sushi, Japanese small plates, and cocktails in a lively modern setting. Good choice for a stylish night out.
Moderate by U.S. standards. Student-oriented spots keep casual food and coffee affordable, while hotels and upscale dining cost more.
Tip 18-20% at restaurants with table service; 15-20% for delivery; USD 1-2 per drink at bars; round up or tip 10-15% for taxis; optional for coffee shops.
Find answers to the most common questions about traveling from Fort Myers, FL to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.

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