The cheapest and fastest buses from Fort Myers, FL to Gainesville, FL
Cheapest price
$75
Average price
$75
Fastest journey
13 h 15 m
Average duration
13 h 15 m
Buses per day
1
Distance
340 km
The best way to find a cheap bus ticket from Fort Myers, FL to Gainesville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Gainesville, FL will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $75.
Of the 1 buses that leave Fort Myers, FL for Gainesville, FL on Sat, Nov 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Nov 22 the direct buses cover the 340 km distance in an average of 13 h 15 m but if you time it right, some buses will get you there in just 13 h 15 m .
On Sat, Nov 22 the slowest buses will take 13 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Fort Myers, FL to Gainesville, FL
Omio recommends booking the bus as it is the most popular option from Fort Myers, FL to Gainesville, FL among Omio's users. If you are prioritising price take the bus with prices starting from €44. For those with little time consider booking a bus which can get you there in 5h 50m. The ticket price range depends on the travel mode: a bus costs an average of €44, and a flight costs an average of €204.
Distance: 211 miles (340 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€55 Average price Cheapest | €469 Average price |
6h 20m Average total duration Fastest 5h 50m Onboard + 30m Additional time* | 15h 9m Average total duration 12h 9m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Fort Myers, FL to Gainesville, FL bus times
The table below shows live departures for Fort Myers, FL to Gainesville, FL buses for tomorrow, Saturday, November 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:35 PM Fort Myers, FL | 13h15 | 11:50 AM Gainesville, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Fort Myers, FL to Gainesville, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 22
Nov 23
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Nov 27
Nov 28
Journey information
Overview: Bus from Fort Myers, FL to Gainesville, FL
Buses from Fort Myers, FL to Gainesville, FL run on average 4 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at $54 (€44) if you book in advance.
The earliest bus runs at 00:25, the last at 22:40. The fastest bus covers the 211 miles (340 km) distance in 8h 25m.
Distance 211 miles (340 km) |
Average bus duration 5h 50m |
Cheapest ticket price $54 (€44) |
Buses per day 4 |
Fastest bus 8h 25m |
First bus 00:25 |
Last bus 22:40 |
Bus providers: FlixBus from Fort Myers, FL to Gainesville, FLYou can travel by bus between Fort Myers, FL to Gainesville, FL with FlixBus for as low as $54 (€44). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Fort Myers, FL to Gainesville, FL
Find answers to the most common questions about traveling from Fort Myers, FL to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Florida Museum of Natural History, featuring extensive exhibits on Florida's flora, fauna, and cultural heritage
- Kanapaha Botanical Gardens, a 62-acre garden showcasing diverse plant collections and scenic landscapes
- Devil's Millhopper Geological State Park, a unique geological formation with a large sinkhole and nature trails
- Paynes Prairie Preserve State Park, offering wildlife viewing, hiking, and panoramic views of the prairie ecosystem
- Samuel P. Harn Museum of Art, housing a diverse collection of artworks from around the world.
- Explore the vibrant local art scene at the Gainesville Artwalk, featuring galleries and live performances
- Visit the Santa Fe College Teaching Zoo, home to a variety of animal species and educational programs
- Enjoy a day of outdoor activities at Lake Wauburg, offering boating, picnicking, and climbing walls
- Discover the historic Haile Homestead, known for its " Talking Walls" filled with writings from the 19th century
- Attend a performance at the Hippodrome Theatre, showcasing plays, films, and special events.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Fort Myers, FL to Gainesville, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Fort Myers, FL to Gainesville, FL
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