4.9
4.6The cheapest and fastest buses from Orlando, FL to Florence, SC
Cheapest price on Sep 19
€60
Average ticket price on Sep 19
€86
Fastest journey on Sep 19
8 h 25 m
Average journey duration on Sep 19
9 h 8 m
Buses on Sep 19
3
Distance
647 km
The best way to find a cheap bus ticket from Orlando, FL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Florence, SC will cost around €86 if you buy it on the day, but the cheapest tickets can be found for only €60.
On Sat, Sep 19, we found 3 buses from Orlando, FL to Florence, SC, including 3 direct services.
On Sat, Sep 19 the direct buses cover the 647 km distance in an average of 9 h 8 m but if you time it right, some buses will get you there in just 8 h 25 m .
On Sat, Sep 19 the slowest buses will take 9 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:00 AM9h35Orlando, FL6:35 PMFlorence, SC€601One-way0 transfers- 8:00 AM9h25Orlando, FL5:25 PMFlorence, SC€931One-way0 transfers
- 7:40 PM8h25Orlando, FL4:05 AMFlorence, SC€1041One-way0 transfers
- 7:40 PM8h25Orlando, FL4:05 AMFlorence, SC€1041One-way0 transfers
- 8:00 AM9h25Orlando, FL5:25 PMFlorence, SC€931One-way0 transfers
- 9:00 AM9h35Orlando, FL6:35 PMFlorence, SC€601One-way0 transfers
Travel Information
Compare train and bus for Orlando, FL to Florence, SC
Omio recommends booking the train as it is the most popular option from Orlando, FL to Florence, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €104 For those with little time, consider booking a bus, which has an average total journey time of 9h 38m. Average ticket prices depend on the travel mode: a bus costs an average of €104, while a train costs an average of €137.
Distance: 402 miles (647 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
€104 Average price Cheapest | €137 Average price | €75 Average price (fuel + tolls) |
9h 38m Average total duration Fastest 9h 8m Onboard + 30m Additional time* | 10h 3m Average total duration 9h 33m Onboard + 30m Additional time* | 6h 28m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Florence, SC:
A bus is €33 less than a train for this route with tickets for a train from Orlando, FL to Florence, SC costing on average €137.
Other travel options to Florence, SC take longer:
Train takes on average 9h 33m.
Tickets start at around €104 compared to roughly €75 in fuel and tolls — a saving of about €-28.42. The journey takes 9h 8m versus 6h 28m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Orlando, FL to Florence, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 04:00AM | Arrival Time 01:25PM | Duration 9h25 | Departure days Wed | Cheapest price €70 |
Operator FlixBus | Departure Time 08:00AM | Arrival Time 05:25PM | Duration 9h25 | Departure days Mon, Sat, Sun | Cheapest price €84 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 06:35PM | Duration 9h35 | Departure days Sat | Cheapest price €60 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 12:05AM | Duration 11h20 | Departure days Thu, Fri | Cheapest price €68 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 12:05AM | Duration 8h25 | Departure days Thu, Fri | Cheapest price €55 |
Operator FlixBus | Departure Time 07:40PM | Arrival Time 04:05AM | Duration 8h25 | Departure days Mon, Sat | Cheapest price €78 |
Live departures
Orlando, FL to Florence, SC bus times
The table below shows live departures for Orlando, FL to Florence, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 12:45 PM Orlando, The Florida Mall, FL | 11h20 | 12:05 AM Florence, W Lucas St (TA Gas Station), SC | 1 transfer | |
| FlixBus | 3:40 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 8h25 | 12:05 AM Florence, W Lucas St (TA Gas Station), SC | 0 transfersDirect | |
| Saturday, September 19 | |||||
| 8:00 AM Orlando, FL | 9h25 | 5:25 PM Florence, SC | 0 transfersDirect | |
| 9:00 AM Orlando, FL | 9h35 | 6:35 PM Florence, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Orlando, FL to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 19
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Sep 23
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Sep 25
Why should you book Orlando, FL to Florence, SC buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Orlando, FL to Florence, SC.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Orlando, FL to Florence, SC.
Journey information
Overview: Bus from Orlando, FL to Florence, SC
USAUSA
Buses from Orlando, FL to Florence, SC run on average 3 times per day, taking around 9h 8m. Cheap bus tickets for this journey start at €59 if you book in advance.
There are 1 buses per day. The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 402 miles (647 km) distance in 8h 10m.
Distance 402 miles (647 km) |
Average bus duration 9h 8m |
Cheapest ticket price €59 |
Buses per day 3 |
Direct buses 1 |
Fastest bus 8h 10m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Bus providers: FlixBus from Orlando, FL to Florence, SCYou can travel by bus between Orlando, FL to Florence, SC with FlixBus for as low as €59. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Orlando, FL to Florence, SC
Find answers to the most common questions about traveling from Orlando, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Florence, SC
Most Orlando, FL to Florence, SC buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Florence, W Lucas St (TA Gas Station) station pair, with some services arriving at Florence, S Irby St (Greyhound Bus Stop). Use this guide to compare Orlando, FL and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Orlando, FL station do buses to Florence, SC leave from?
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Getting to Orlando, The Florida Mall from Orlando city centre
Which Florence, SC station do buses from Orlando, FL arrive at?
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Florence, SC
Here are some other resources that might have the information you need
Most popular buses to and from Florence, SC and Orlando, FL
Most popular bus connections to Florence, SC
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