Roanoke, VA to Florence, SC bus with Greyhound

Sun, Dec 21
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FlixBus
Alsa
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Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Roanoke, VA to Florence, SC

Showing times and prices for Dec 21

Cheapest price

$284

Average price

$284

Fastest journey

1 d 19 h 20 m

Average duration

1 d 19 h 20 m

Buses per day

1

Distance

342 km

Cheap tickets

The best way to find a cheap bus ticket from Roanoke, VA to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Roanoke, VA to Florence, SC will cost around $284 if you buy it on the day, but the cheapest tickets can be found for only $284.

Fast buses

It's difficult to get from Roanoke, VA to Florence, SC without transferring at least 3 times.

Greyhound USA
12:35PM43h20
Roanoke, VA
07:55AMFlorence, SC
$2841One-way
3 transfers

Travel Information

Compare train and bus for Roanoke, VA to Florence, SC

Omio recommends booking the train as it is the most popular option from Roanoke, VA to Florence, SC among Omio's users. If you are prioritising price take the train with prices starting from €144. For those with little time consider booking a train which can get you there in 20h 55m. The ticket price range depends on the travel mode: a train costs an average of €144, and a bus costs an average of €231.

Distance: 212 miles (342 km)

Compare bus with

Bus
Most popular
Train

€231

Average price

€222

Average price

Cheapest

43h 50m

Average total duration

43h 20m

Onboard

+

30m

Additional time*

21h 25m

Average total duration

Fastest

20h 55m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

Roanoke, VA to Florence, SC bus times

The table below shows live departures for Roanoke, VA to Florence, SC buses for tomorrow, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 11:18 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:35 PM Roanoke, VA
43h20
7:55 AM Florence, SC3 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Roanoke, VA to Florence, SC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Dec 21
Mon
Dec 22
Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
Sat
Dec 27

Journey information

Overview: Bus from Roanoke, VA to Florence, SC

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Buses from Roanoke, VA to Florence, SC run on average 1 times per day, taking around 43h 20m. Cheap bus tickets for this journey start at $288 (€231) but you can travel from only $179 (€144) by train.

The earliest bus runs at 12:35, the last at 12:35. The fastest bus covers the 212 miles (342 km) distance in 43h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $179 (€144)
Distance
212 miles (342 km)
Average bus duration
43h 20m
Cheapest ticket price
$288 (€231)
Buses per day
1
Fastest bus
43h 20m
First bus
12:35
Last bus
12:35
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $179 (€144)

Bus providers: Greyhound from Roanoke, VA to Florence, SCYou can travel by bus between Roanoke, VA to Florence, SC with Greyhound for as low as $179 (€144). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
43h 20m
Cheapest Price
$286 (€229)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Roanoke, VA to Florence, SC

Find answers to the most common questions about traveling from Roanoke, VA to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Roanoke, VA to Florence, SC can start from as little as $322 (€258) when you book in advance. The average bus ticket price for Roanoke, VA to Florence, SC is $322 (€258); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Roanoke, VA to Florence, SC bus time is 43 h 20 min   covering the 212 mile (342 km) long route, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The bus from Roanoke, VA to Florence, SC leaves at 4: 15PM. Plan your trip with the Journey Planner   from Omio.
There is 1 bus a day from Roanoke, VA to Florence, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Roanoke, VA to Florence, SC, you can count on Greyhound for the best way to get you to Florence, SC. You can also check all possible bus companies who offer a service to Florence, SC from Roanoke, VA and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 2 ways to travel between Roanoke, VA and Florence, SC including taking a train or bus.
Yes, the following accessibility options are available when taking the bus from Roanoke, VA to Florence, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Roanoke, VA to Florence, SC for bus company Greyhound.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Roanoke, VA to Florence, SC depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Roanoke, VA to Florence, SC, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Roanoke, VA to Florence, SC.
    Yes, the following luggage options are included when booking a bus ticket from Roanoke, VA to Florence, SC:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Roanoke, VA to Florence, SC:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from Roanoke, VA to Florence, SC.
    You can reserve your seat on the bus from Roanoke, VA to Florence, SC with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from Roanoke, VA to Florence, SC with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from Roanoke, VA to Florence, SC with the following bus company: Greyhound.

    More options for your journey from Roanoke, VA to Florence, SC

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