Roanoke, VA to Florence, SC bus

Tue, Nov 03
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Journey information

Overview: Bus from Roanoke, VA to Florence, SC

USAUSA
USAUSA
Icon of bus

Take a bus from Roanoke, VA to Florence, SC and enjoy the approximately 212 miles (342 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
212 miles (342 km)
High Season
Oct - Dec
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Complete guide to Florence, SC

Things to do in Florence, SC

Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.

  • Must visit

Uffizi Gallery

Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.

  • Must visit

Galleria dell'Accademia

Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.

  • Recommended

Museo dell'Opera del Duomo

Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.

$ US Dollar

Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.

Average meal costs

Budget
$8-12 for fast food or casual takeout.
Mid-range
$15-25 per person for a casual sit-down meal.
Fine dining
$35+ per person for upscale restaurants.
Coffee
$3-5 for regular coffee or latte.

Tipping culture

Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.

Plan your visit to Florence, SC

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Florence, SC.

The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Bus from Roanoke, VA to Florence, SC

Find answers to the most common questions about traveling from Roanoke, VA to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Yes, you can take a between Roanoke, VA and Florence, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

More options for your journey from Roanoke, VA to Florence, SC

Here are some other resources that might have the information you need

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone