Roanoke, VA to Florence, SC bus with Greyhound

Wed, May 06
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2,000+ travel companies
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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Travel Information

Compare bus for Roanoke, VA to Florence, SC

Omio recommends booking the train as it is the most popular option from Roanoke, VA to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $284. For those with little time consider booking a train which can get you there in 25h 29m. The ticket price range depends on the travel mode: a bus costs an average of $284, and a train costs an average of $491.

Distance: 212 miles (342 km)

Compare bus with

Bus
Most popular
Train

$284

Average price

Cheapest

$491

Average price

43h 50m

Average total duration

43h 20m

Onboard

+

30m

Additional time*

25h 59m

Average total duration

Fastest

25h 29m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Why should you book Roanoke, VA to Florence, SC buses with Omio?

Greyhound operates all buses services from Roanoke, VA to Florence, SC.
Omio is an official ticket reseller for all your travel options from Roanoke, VA to Florence, SC.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Roanoke, VA to Florence, SC

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Buses from Roanoke, VA to Florence, SC run on average 1 times per day, taking around 43h 20m. Cheap bus tickets for this journey start at $284 (€228) if you book in advance.

The earliest bus runs at 12:35, the last at 12:35. The fastest bus covers the 212 miles (342 km) distance in 43h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
212 miles (342 km)
Average bus duration
43h 20m
Cheapest ticket price
$284 (€228)
Buses per day
1
Fastest bus
43h 20m
First bus
12:35 PM
Last bus
12:35 PM
High Season
Oct - Dec
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Roanoke, VA to Florence, SCYou can travel by bus between Roanoke, VA to Florence, SC with Greyhound for as low as $284 (€228). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
43h 20m
Cheapest Price
$284 (€228)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Roanoke, VA to Florence, SC

Find answers to the most common questions about traveling from Roanoke, VA to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Roanoke, VA to Florence, SC can start from as little as $284 (€228) when you book in advance. The average bus ticket price for Roanoke, VA to Florence, SC is $284 (€228) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Roanoke, VA to Florence, SC is 43h 20m to travel the 212 miles (342 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Roanoke, VA to Florence, SC leaves at 12:35 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Roanoke, VA to Florence, SC leaves at 12:35 PM.
There are 1 buses a day from Roanoke, VA to Florence, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Roanoke, VA to Florence, SC, you can count on Greyhound for the best way to get you to Florence, SC. You can also check all possible bus companies who offer a service between Roanoke, VA and Florence, SC and compare the amenities they offer before buying a bus ticket.
A trip to Florence, SC from Roanoke, VA is worth doing but not as a day trip with a journey time of 43h 20m each way. Check with Omio app the best way to travel.
Yes, you can take a between Roanoke, VA and Florence, SC.
Yes, the following accessibility options are available when taking the bus from Roanoke, VA to Florence, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Roanoke, VA to Florence, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Roanoke, VA to Florence, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Roanoke, VA to Florence, SC.
Yes, the following luggage options are included when booking a bus ticket from Roanoke, VA to Florence, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Roanoke, VA to Florence, SC:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Roanoke, VA to Florence, SC.
You can reserve your seat on the bus from Roanoke, VA to Florence, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Roanoke, VA to Florence, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Roanoke, VA to Florence, SC with the following bus company: Greyhound.
Since neither Roanoke, VA nor Florence, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Roanoke, VA to Florence, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

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