- Must visit
Uffizi Galleries
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Omio recommends booking the train as it is the most popular option from Miami, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $208. For those with little time consider booking a train which can get you there in 15h 17m. The ticket price range depends on the travel mode: a bus costs an average of $208, and a train costs an average of $325.
Distance: 582 miles (937 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$208 Average price Cheapest | $325 Average price | $131 Average price (fuel + tolls) |
18h 50m Average total duration 18h 20m Onboard + 30m Additional time* | 15h 47m Average total duration Fastest 15h 17m Onboard + 30m Additional time* | 9h 28m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Miami, FL to Florence, SC:
A bus is $117 (€96) less than a train for this route with tickets for a train from Miami, FL to Florence, SC costing on average $325 (€266).
Other travel options to Florence, SC take longer:
Bus takes on average 18h 20m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Flixbus USA | Departure Time 07:30PM | Arrival Time 01:25PM | Duration 17h55 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $128 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 05:25PM | Duration 18h20 | Departure days Sun | Cheapest price $208 |
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Miami, FL to Florence, SC run on average 8 times per day, taking around 18h 20m. Cheap bus tickets for this journey start at $208 (€170) if you book in advance.
The earliest bus runs at 00:05, the last at 23:25. The fastest bus covers the 582 miles (937 km) distance in 18h 20m.
Distance 582 miles (937 km) |
Average bus duration 18h 20m |
Cheapest ticket price $208 (€170) |
Buses per day 8 |
Fastest bus 18h 20m |
First bus 12:05 AM |
Last bus 11:25 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 21 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Best known for Michelangelo’s David, this compact museum is one of Florence’s essential stops. Advance booking is commonly recommended because queues can be long.
Large palace museum complex with royal apartments, paintings, and design collections. Worth visiting for its scale, courtly interiors, and links to Medici history.
The monumental heart of Florence, surrounded by the cathedral, dome, baptistery, and bell tower. Essential for first-time visitors and classic city views.
Historic square lined with civic architecture and open-air sculptures. One of Florence’s liveliest public spaces and a key stop on any walking route.
The city’s most famous viewpoint, especially popular at sunset for sweeping skyline photos. A social media favorite and classic Florence panorama.
Slow-smoked pork shoulder, usually chopped or pulled and served with a tangy Southern barbecue sauce. It is a staple across the Carolinas and common in Florence-area smokehouses.
Cornmeal-coated catfish fillets fried until crisp, often served with hush puppies and slaw. This is a classic Pee Dee and broader South Carolina comfort dish.
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a light sauce. A defining Lowcountry and South Carolina dish regularly found in Florence.
Established downtown barbecue spot specializing in smoked meats, Southern sides, and a casual local atmosphere.
Upscale, long-running Florence restaurant known for steaks, seafood, and polished Southern-American dining in an elegant setting.
Well-known casual seafood restaurant recognized for fried seafood platters, shrimp, fish, and regional comfort fare.
Costs are moderate for the U.S. Budget eats are easy to find, while hotels and fine dining can raise daily costs.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff USD 2-5 for helpful service.
Find answers to the most common questions about traveling from Miami, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Miami, FL to Florence, SC buses use the Miami, Airport Intermodal Station to Florence, S Irby St (Greyhound Bus Stop) station pair. Use this guide to compare Miami, FL and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need