- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Cheapest price
$32
Average price
$32
Fastest journey
5 h
Average duration
5 h 17 m
Buses per day
7
Distance
218 km
The best way to find a cheap bus ticket from Fort Myers, FL to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Orlando, FL will cost around $32 if you buy it on the day, but the cheapest tickets can be found for only $32.
Of the 7 buses that leave Fort Myers, FL for Orlando, FL on Thu, Jul 30, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 30 the direct buses cover the 218 km distance in an average of 5 h 17 m but if you time it right, some buses will get you there in just 5 h .
On Thu, Jul 30 the slowest buses will take 5 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
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FlixBus
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FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Fort Myers, FL to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $28. For those with little time consider booking a bus which can get you there in 5h 32m. The ticket price range depends on the travel mode: a bus costs an average of $28, and a flight costs an average of $429.
Distance: 135 miles (218 km)
Most popular Bus | Flight | Driving |
|---|---|---|
$45 Average price Cheapest | $480 Average price | $34 Average price (fuel + tolls) |
6h 2m Average total duration Fastest 5h 32m Onboard + 30m Additional time* | 12h 46m Average total duration 9h 46m Onboard + 3h 0m Additional time* | 3h 2m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Fort Myers, FL to Orlando, FL:
A bus is $435 (€358) less than a flight for this route with tickets for a flight from Fort Myers, FL to Orlando, FL costing on average $480 (€396).
Other travel options to Orlando, FL take longer:
Flight takes on average 9h 46m.
You'll arrive about -3h -30m sooner (5h 32m by bus vs 3h 2m by car) and save roughly $-11.20 (€-9.23) compared to fuel and tolls ($45 (€37) vs $34 (€28)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 06:00AM | Arrival Time 06:34PM | Duration 12h34 | Departure days Fri, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 04:10PM | Duration 5h15 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $32 |
Operator Amtrak | Departure Time 11:45AM | Arrival Time 06:34PM | Duration 6h49 | Departure days Fri, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 06:25PM | Duration 6h05 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $32 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 07:30PM | Duration 5h30 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $32 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 10:25PM | Duration 6h05 | Departure days Mon | Cheapest price $44 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 11:00PM | Duration 5h40 | Departure days Mon | Cheapest price $36 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 11:25PM | Duration 5h10 | Departure days Mon | Cheapest price $44 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 03:40AM | Duration 9h10 | Departure days Tue | Cheapest price $57 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 12:35AM | Duration 5h40 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 07:35PM | Arrival Time 01:25AM | Duration 5h50 | Departure days Mon | Cheapest price $47 |
Operator FlixBus | Departure Time 10:20PM | Arrival Time 03:20AM | Duration 5h00 | Departure days Mon | Cheapest price $48 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 04:20AM | Duration 5h00 | Departure days Mon | Cheapest price $53 |
The table below shows live departures for Fort Myers, FL to Orlando, FL buses for today, Wednesday, July 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 6:55 PM Fort Myers, Rosa Parks Transit Center | 5h40 | 12:35 AM Orlando, The Florida Mall, FL | 0 transfersDirect | |
FlixBus | 6:55 PM Fort Myers, Rosa Parks Transit Center | 5h00 | 11:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 0 transfersDirect | |
| Thursday, July 30 | |||||
FlixBus | 10:55 AM Fort Myers, Rosa Parks Transit Center | 5h15 | 4:10 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 0 transfersDirect | |
FlixBus | 10:55 AM Fort Myers, Rosa Parks Transit Center | 5h50 | 4:45 PM Orlando, The Florida Mall, FL | 0 transfersDirect | |
FlixBus | 12:20 PM Fort Myers, Rosa Parks Transit Center | 6h05 | 6:25 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 0 transfersDirect | |
FlixBus | 2:00 PM Fort Myers, Rosa Parks Transit Center | 5h30 | 7:30 PM Orlando, The Florida Mall, FL | 0 transfersDirect | |
FlixBus | 2:00 PM Fort Myers, Rosa Parks Transit Center | 5h00 | 7:00 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Fort Myers, FL to Orlando, FL run on average 9 times per day, taking around 5h 32m. Cheap bus tickets for this journey start at $28 (€23) if you book in advance.
There are 7 buses per day. The earliest bus runs at 04:35, the last at 23:40. The fastest bus covers the 135 miles (218 km) distance in 5h 0m.
Distance 135 miles (218 km) |
Average bus duration 5h 32m |
Cheapest ticket price $28 (€23) |
Buses per day 9 |
Direct buses 7 |
Fastest bus 5h 0m |
First bus 4:35 AM |
Last bus 11:40 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Fri |
Best time to book 28 days |
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from Fort Myers, FL to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Fort Myers, FL to Orlando, FL buses use the Fort Myers, Rosa Parks Transit Center to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Fort Myers, FL and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need