The cheapest and fastest buses from Fort Myers, FL to Buffalo, NY
Cheapest price
$310
Average price
$363
Fastest journey
1 d 21 h 10 m
Average duration
2 d 33 m
Buses per day
2
Distance
1828 km
The best way to find a cheap bus ticket from Fort Myers, FL to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Fort Myers, FL to Buffalo, NY will cost around $363 if you buy it on the day, but the cheapest tickets can be found for only $310.
Of the 2 buses that leave Fort Myers, FL for Buffalo, NY on Tue, Mar 03, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 03 the direct buses cover the 1828 km distance in an average of 2 d 33 m but if you time it right, some buses will get you there in just 1 d 21 h 10 m .
On Tue, Mar 03 the slowest buses will take 2 d 3 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Fort Myers, FL to Buffalo, NY
Omio recommends booking the bus as it is the most popular option from Fort Myers, FL to Buffalo, NY among Omio's users. If you are prioritising price take the flight with prices starting from $179. For those with little time consider booking a flight which can get you there in 4h 6m. The ticket price range depends on the travel mode: a flight costs an average of $179, and a train costs an average of $359.
Distance: 1135 miles (1828 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$308 Average price | $301 Average price Cheapest | $559 Average price |
38h 5m Average total duration 37h 35m Onboard + 30m Additional time* | 7h 6m Average total duration Fastest 4h 6m Onboard + 3h 0m Additional time* | 36h 51m Average total duration 36h 21m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Fort Myers, FL to Buffalo, NY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
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Mar 09
Why should you book Fort Myers, FL to Buffalo, NY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Fort Myers, FL to Buffalo, NY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Fort Myers, FL to Buffalo, NY.
Journey information
Overview: Bus from Fort Myers, FL to Buffalo, NY
Buses from Fort Myers, FL to Buffalo, NY run on average 6 times per day, taking around 37h 35m. Cheap bus tickets for this journey start at $158 (€126) if you book in advance.
The earliest bus runs at 04:18, the last at 23:55. The fastest bus covers the 1135 miles (1828 km) distance in 45h 10m.
Distance 1135 miles (1828 km) |
Average bus duration 37h 35m |
Cheapest ticket price $158 (€126) |
Buses per day 6 |
Fastest bus 45h 10m |
First bus 04:18 |
Last bus 23:55 |
Bus providers: Greyhound from Fort Myers, FL to Buffalo, NYYou can travel by bus between Fort Myers, FL to Buffalo, NY with Greyhound for as low as $158 (€126). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Fort Myers, FL to Buffalo, NY
Find answers to the most common questions about traveling from Fort Myers, FL to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Fort Myers, FL to Buffalo, NY
More options for your journey from Fort Myers, FL to Buffalo, NY
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