Tampa, FL to Florence, SC bus with Greyhound

Wed, Feb 04
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Costa Verde
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1,000+ travel companies
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Travel Information

Compare train for Tampa, FL to Florence, SC

Omio recommends booking the train as it is the most popular option from Tampa, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from €91. For those with little time consider booking a train which can get you there in 11h 45m. The ticket price range depends on the travel mode: a bus costs an average of €91, and a train costs an average of €86.

Distance: 460 miles (741 km)

Compare bus with

Bus
Most popular
Train

€102

Average price

Cheapest

€127

Average price

13h 59m

Average total duration

13h 29m

Onboard

+

30m

Additional time*

12h 15m

Average total duration

Fastest

11h 45m

Onboard

+

30m

Additional time*

Greyhound

Most popular bus company

Amtrak

Most popular train company

Direct Options

Direct Options

Compare prices and tickets Tampa, FL to Florence, SC by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Tampa, FL to Florence, SC buses with Omio?

Greyhound operates all buses services from Tampa, FL to Florence, SC.
Omio is an official ticket reseller for all your travel options from Tampa, FL to Florence, SC.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Tampa, FL to Florence, SC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Why book with Omio over Wanderu?

    Journey information

    Overview: Bus from Tampa, FL to Florence, SC

    USAUSA
    USAUSA
    Icon of bus

    Buses from Tampa, FL to Florence, SC run on average 6 times per day, taking around 13h 29m. Cheap bus tickets for this journey start at $115 (€91) but you can travel from only $108 (€86) by train.

    The earliest bus runs at 03:18, the last at 22:35. The fastest bus covers the 460 miles (741 km) distance in 15h 45m.

    Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
    Price information
    Cheapest alternative travel mode
    Train from $108 (€86)
    Distance
    460 miles (741 km)
    Average bus duration
    13h 29m
    Cheapest ticket price
    $115 (€91)
    Buses per day
    6
    Fastest bus
    15h 45m
    First bus
    03:18
    Last bus
    22:35
    Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
    Price information
    Cheapest alternative travel mode
    Train from $108 (€86)

    Bus providers: Greyhound from Tampa, FL to Florence, SCYou can travel by bus between Tampa, FL to Florence, SC with Greyhound for as low as $108 (€86). When you search for schedules and tickets, Omio will show you the best journey

    Greyhound

    About
    Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
    Luggage & cancellation policy
    Average Duration
    14h 29m
    Cheapest Price
    $134 (€107)
    Greyhound frequency
    3 a day
    Luggage included
    One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Additional luggage
    $15 per additional bag.
    Cancellation Policy
    You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
    Amenities on board the bus
    Wifi
    Food sold onboard
    Seat reservation
    Toilets
    USB plugs
    Accessibility
    Assistance; Priority seating; Wheelchair-accessible buses.
    Bikes
    Bikes are allowed.

    FAQs: Bus from Tampa, FL to Florence, SC

    Find answers to the most common questions about traveling from Tampa, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

    FAQs
    Cheap bus tickets from Tampa, FL to Florence, SC can start from as little as $115 (€91) when you book in advance. The average bus ticket price for Tampa, FL to Florence, SC is $128 (€102) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
    The average journey time by bus from Tampa, FL to Florence, SC is 15h 45m to travel the 460 miles (741 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
    The earliest bus from Tampa, FL to Florence, SC leaves at 3:18 AM. Plan your trip with the Journey Planner from Omio.
    The latest bus from Tampa, FL to Florence, SC leaves at 10:35 PM.
    There are 6 buses a day from Tampa, FL to Florence, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
    When taking a bus from Tampa, FL to Florence, SC, you can count on Greyhound for the best way to get you to Florence, SC. You can also check all possible bus companies who offer a service between Tampa, FL and Florence, SC and compare the amenities they offer before buying a bus ticket.
    A trip to Florence, SC from Tampa, FL is worth doing but not as a day trip with a journey time of 15h 45m each way. Check with Omio app the best way to travel.
    The cheapest month for a bus from Tampa, FL to Florence, SC is May.
    Yes, you can take a train between Tampa, FL and Florence, SC.
    Yes, the following accessibility options are available when taking the bus from Tampa, FL to Florence, SC:
    • Greyhound
      • Assistance
      • Priority seating
      • Wheelchair-accessible buses.
    Yes, there are bathrooms on board the bus from Tampa, FL to Florence, SC for bus company Greyhound.
    Whether you can cancel your bus ticket from Tampa, FL to Florence, SC depends on the bus companies:
    • Greyhound
      • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
    Yes, bikes are allowed on board the bus with bus company Greyhound.
    Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
    Yes, there is food available to purchase on board the bus from Tampa, FL to Florence, SC.
    Yes, the following luggage options are included when booking a bus ticket from Tampa, FL to Florence, SC:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Tampa, FL to Florence, SC:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from Tampa, FL to Florence, SC.
    You can reserve your seat on the bus from Tampa, FL to Florence, SC with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from Tampa, FL to Florence, SC with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from Tampa, FL to Florence, SC with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from Tampa, FL to Florence, SC

    Tampa
    Florence
    The major bus station for departures in Tampa is Tampa, Marion Transit Center. Find all the information you need to know about services, amenities and connections at Tampa, Marion Transit Center for your trip from Tampa to Florence.
    Tampa, Marion Transit Center
    information
    Tampa, USF Holly Drive (Central Plant)
    information

    More options for your journey from Tampa, FL to Florence, SC

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