Travel Information
Compare train for Tampa, FL to Florence, SC
Omio recommends booking the train as it is the most popular option from Tampa, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from €91. For those with little time consider booking a train which can get you there in 11h 45m. The ticket price range depends on the travel mode: a bus costs an average of €91, and a train costs an average of €86.
Distance: 460 miles (741 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€102 Average price Cheapest | €127 Average price |
13h 59m Average total duration 13h 29m Onboard + 30m Additional time* | 12h 15m Average total duration Fastest 11h 45m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Compare prices and tickets Tampa, FL to Florence, SC by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Tampa, FL to Florence, SC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Tampa, FL to Florence, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu?
Journey information
Overview: Bus from Tampa, FL to Florence, SC
Buses from Tampa, FL to Florence, SC run on average 6 times per day, taking around 13h 29m. Cheap bus tickets for this journey start at $115 (€91) but you can travel from only $108 (€86) by train.
The earliest bus runs at 03:18, the last at 22:35. The fastest bus covers the 460 miles (741 km) distance in 15h 45m.
Distance 460 miles (741 km) |
Average bus duration 13h 29m |
Cheapest ticket price $115 (€91) |
Buses per day 6 |
Fastest bus 15h 45m |
First bus 03:18 |
Last bus 22:35 |
Bus providers: Greyhound from Tampa, FL to Florence, SCYou can travel by bus between Tampa, FL to Florence, SC with Greyhound for as low as $108 (€86). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Tampa, FL to Florence, SC
Find answers to the most common questions about traveling from Tampa, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Tampa, FL to Florence, SC
Most popular bus connections from Tampa, FL
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