- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities, and decorative arts.
Cheapest price
$129
Average price
$129
Fastest journey
9 h 7 m
Average duration
11 h 53 m
Trains per day
2
Distance
493 km
The best way to find a cheap train ticket from Pisa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Lyon will cost around $129 if you buy it on the day, but the cheapest tickets can be found for only $129.
It's difficult to get from Pisa to Lyon without transferring at least 2 times.




Omio recommends booking the bus as it is the most popular option from Pisa to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a train which can get you there in 7h 51m. The ticket price range depends on the travel mode: a bus costs an average of $53, and a flight costs an average of $105.
Distance: 306 miles (493 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$129 Average price | $88 Average price Cheapest | $504 Average price | $286 Average price (fuel + tolls) |
8h 21m Average total duration Fastest 7h 51m Onboard + 30m Additional time* | 11h 26m Average total duration 10h 56m Onboard + 30m Additional time* | 18h 27m Average total duration 15h 27m Onboard + 3h 0m Additional time* | 7h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa to Lyon:
A bus is $41 (€34) less than a train for this route with tickets for a train from Pisa to Lyon costing on average $129 (€106).
A bus is $417 (€343) less than a flight for this route with tickets for a flight from Pisa to Lyon costing on average $504 (€415).
Other travel options to Lyon take longer:
Bus takes on average 10h 56m.
Flight takes on average 15h 27m.
Tickets start at around $129 (€106) compared to roughly $286 (€235) in fuel and tolls — a saving of about $157 (€129). The journey takes 7h 51m versus 7h 32m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Pisa to Lyon trains for today, Saturday, July 11. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:25 AM Pisa | 9h07 | 8:32 PM Lyon | 2 transfers | |
![]() | 8:34 PM Pisa | 14h38 | 11:12 AM Lyon | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa to Lyon run on average 1 times per day, taking around 7h 51m. Cheap train tickets for this journey start at $129 (€106) but you can travel from only $53 (€44) by bus.
The earliest train runs at 00:25, the last at 20:20. The fastest train covers the 306 miles (493 km) distance in 9h 7m.
Distance 306 miles (493 km) |
Average train duration 7h 51m |
Cheapest ticket price $129 (€106) |
Trains per day 1 |
Fastest train 9h 7m |
First train 12:25 AM |
Last train 8:20 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Best time to book 4 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections of painting, sculpture, antiquities, and decorative arts.
Archaeological museum and Roman theatres complex explaining ancient Lugdunum, the Roman city that became Lyon.
Striking science and society museum at the confluence of the Rhône and Saône, known for its architecture and immersive exhibitions.
Lyon's atmospheric old town, famous for Renaissance streets, traboules, and lively pedestrian lanes.
The central peninsula between the Rhône and Saône, packed with shopping streets, squares, and classic city architecture.
One of Europe's largest open squares, a key meeting point and base for exploring central Lyon.
Light dumplings traditionally made with pike and served with a rich Nantua crayfish sauce, a classic of Lyonnais cuisine.
A traditional Lyon salad with frisée, lardons, croutons, and a poached egg, widely served in local bouchons.
Pork sausage baked inside brioche, a beloved Lyon specialty that reflects the city’s charcuterie tradition.
Legendary fine-dining institution with deep Lyon culinary heritage and polished, high-end tasting menus.
Popular modern bouchon known for refined takes on Lyon classics and a warm, intimate atmosphere.
Well-known traditional bouchon serving classic Lyonnais dishes in a lively, rustic setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Small change or rounding up is appreciated; 5-10% only for exceptional service. Taxis are usually rounded up, and tips in bars or cafes are modest.
Official public transport app
Lyon Part-Dieu -> Place Bellecour, Lyon
Find answers to the most common questions about traveling from Pisa to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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