- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
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The cheapest and fastest trains from Pisa to Lyon
Showing times and prices for May 27
Cheapest price
$197
Average price
$229
Fastest journey
9 h 19 m
Average duration
10 h 5 m
Trains per day
14
Distance
493 km
Cheap tickets
The best way to find a cheap train ticket from Pisa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Lyon will cost around $229 if you buy it on the day, but the cheapest tickets can be found for only $197.
Fast trains
It's difficult to get from Pisa to Lyon without transferring at least 2 times.
Intercity 658+
FRECCIAROSSA 1000 92965:42 AM14h50Pisa Centrale8:32 PMLyon Part Dieu$1971One-way1 transfer
Regionale 19388 · Regionale Veloce 3261 · Regionale Veloce 3028+FRECCIAROSSA 1000 92968:18 AM12h14Pisa Centrale8:32 PMLyon Part Dieu$2041One-way3 transfers
InterCityNotte 796+Regionale Veloce 3019+FRECCIAROSSA 1000 92964:27 AM16h05Pisa Centrale8:32 PMLyon Part Dieu$2061One-way2 transfers- Intercity 662+FRECCIAROSSA 1000 92966:42 AM13h50Pisa Centrale8:32 PMLyon Part Dieu$2071One-way1 transfer
- Intercity 666+FRECCIAROSSA 1000 92968:55 AM11h37Pisa Centrale8:32 PMLyon Part Dieu$2071One-way1 transfer
- Regionale 32788+
FRECCIAROSSA 9514+FRECCIAROSSA 1000 929611:13 AM9h19Pisa Centrale8:32 PMLyon Part Dieu$2431One-way2 transfers - Regionale 4028+FRECCIAROSSA 9416 · FRECCIAROSSA 8814+FRECCIAROSSA 1000 929611:09 AM9h23Pisa Centrale8:32 PMLyon Part Dieu$2571One-way3 transfers
- Regionale Veloce 4026+FRECCIAROSSA 9524+FRECCIAROSSA 1000 929610:32 AM10h00Pisa Centrale8:32 PMLyon Part Dieu$2391One-way2 transfers
- InterCityNotte 794+Intercity 745+FRECCIAROSSA 1000 92969:49 AM10h43Pisa Centrale8:32 PMLyon Part Dieu$2141One-way2 transfers
- Regionale Veloce 4020+FRECCIAROSSA 9520+FRECCIAROSSA 1000 92969:32 AM11h00Pisa Centrale8:32 PMLyon Part Dieu$2431One-way2 transfers
Travel Information
Compare train, bus, and flight for Pisa to Lyon
Omio recommends booking the bus as it is the most popular option from Pisa to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $54. For those with little time consider booking a train which can get you there in 7h 51m. The ticket price range depends on the travel mode: a bus costs an average of $54, and a flight costs an average of $107.
Distance: 306 miles (493 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$131 Average price | $89 Average price Cheapest | $514 Average price | $292 Average price (fuel + tolls) |
8h 21m Average total duration Fastest 7h 51m Onboard + 30m Additional time* | 11h 26m Average total duration 10h 56m Onboard + 30m Additional time* | 18h 27m Average total duration 15h 27m Onboard + 3h 0m Additional time* | 7h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Pisa to Lyon is a bus with an average price of $89 (€72).
This is compared to other travel options from Pisa to Lyon:
A bus is $42 (€34) less than a train for this route with tickets for a train from Pisa to Lyon costing on average $131 (€106).
A bus is $424 (€343) less than a flight for this route with tickets for a flight from Pisa to Lyon costing on average $514 (€415).
The fastest way to travel from Pisa to Lyon is by train with an average journey time of 7h 51m.
Other travel options to Lyon take longer:
Bus takes on average 10h 56m.
Flight takes on average 15h 27m.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Lyon including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from Pisa to Lyon among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $131 (€106) compared to roughly $292 (€235) in fuel and tolls — a saving of about $160 (€129). The journey takes 7h 51m versus 7h 32m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Pisa to Lyon train times
The table below shows live departures for Pisa to Lyon trains for tomorrow, Wednesday, May 27. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| InterCityNotte 796+Regionale Veloce 3019+FRECCIAROSSA 1000 9296 | 4:27 AM Pisa Centrale | 16h05 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Intercity 658+FRECCIAROSSA 1000 9296 | 5:42 AM Pisa Centrale | 14h50 | 8:32 PM Lyon Part Dieu | 1 transfer | |
| Regionale 18260+FRECCIAROSSA 9508+FRECCIAROSSA 1000 9296 | 6:29 AM Pisa Centrale | 14h03 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Intercity 662+FRECCIAROSSA 1000 9296 | 6:42 AM Pisa Centrale | 13h50 | 8:32 PM Lyon Part Dieu | 1 transfer | |
| Regionale Veloce 4014+FRECCIAROSSA 9512+FRECCIAROSSA 1000 9296 | 7:38 AM Pisa Centrale | 12h54 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Regionale 19388 · Regionale Veloce 3261 · Regionale Veloce 3028+FRECCIAROSSA 1000 9296 | 8:18 AM Pisa Centrale | 12h14 | 8:32 PM Lyon Part Dieu | 3 transfers | |
| Regionale Veloce 4016+FRECCIAROSSA 9516+FRECCIAROSSA 1000 9296 | 8:32 AM Pisa Centrale | 12h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Intercity 666+FRECCIAROSSA 1000 9296 | 8:55 AM Pisa Centrale | 11h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
| Regionale Veloce 4018+FRECCIAROSSA 9490 · FRECCIAROSSA 8810+FRECCIAROSSA 1000 9296 | 9:09 AM Pisa Centrale | 11h23 | 8:32 PM Lyon Part Dieu | 3 transfers | |
| Regionale Veloce 4020+FRECCIAROSSA 9520+FRECCIAROSSA 1000 9296 | 9:32 AM Pisa Centrale | 11h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Intercity 745+FRECCIAROSSA 1000 9296+InterCityNotte 794 | 9:49 AM Pisa Centrale | 10h43 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Regionale Veloce 4026+FRECCIAROSSA 9524+FRECCIAROSSA 1000 9296 | 10:32 AM Pisa Centrale | 10h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
| Regionale 4028+FRECCIAROSSA 9416 · FRECCIAROSSA 8814+FRECCIAROSSA 1000 9296 | 11:09 AM Pisa Centrale | 9h23 | 8:32 PM Lyon Part Dieu | 3 transfers | |
| Regionale 32788+FRECCIAROSSA 9514+FRECCIAROSSA 1000 9296 | 11:13 AM Pisa Centrale | 9h19 | 8:32 PM Lyon Part Dieu | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 27
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Why should you book Pisa to Lyon trains with Omio?
Trenitalia as well as Regionale offer trains services from Pisa to Lyon.
Omio is an official ticket reseller for all your travel options from Pisa to Lyon.
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Regionale to find the best option for your trip from Pisa to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Lyon.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Lyon.
Journey information
Overview: Train from Pisa to Lyon
Italy
France
Trains from Pisa to Lyon run on average 1 times per day, taking around 7h 51m. Cheap train tickets for this journey start at $131 (€106) but you can travel from only $54 (€44) by bus.
The earliest train runs at 00:25, the last at 20:20. The fastest train covers the 306 miles (493 km) distance in 9h 7m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $54 (€44)
Distance 306 miles (493 km) |
Average train duration 7h 51m |
Cheapest ticket price $131 (€106) |
Trains per day 1 |
Fastest train 9h 7m |
First train 12:25 AM |
Last train 8:20 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Best time to book 4 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $54 (€44)
Train companies: Trenitalia, Regionale from Pisa to Lyon trainsTrenitalia, Regionale trains will get you between Pisa and Lyon from $54 (€44). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
About
Trenitalia is not only Italy's national railroad company but also the country's largest train operator. Trenitalia’s fleet of trains ncludes the high-speed Frecciarossa, Frecciargento and Frecciabianca trains as well as intercity, regional and night trains. Bathrooms and WiFi access are standard on long-distance routes. In most cases, the trains also provide barrier-free access. Trenitalia offers different tickets, which vary in price and flexibility: Base, Economy, Super Economy and Ordinaria. You can even use Trenitalia discount cards on Omio. Make sure to look out for the latest offers from Trenitalia on Omio to score special deals!
Luggage & cancellation policy
Luggage included
2 pieces of hand luggage per passenger included in ticket price
Luggage storage
Overhead racks, luggage areas at end of carriages, and spaces between seat backs
Cancellation Policy
Cancellation policies vary by ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car on high-speed trains, trolley service with snacks and beverages, vending machines on some trains
Seat reservation
Optional seat reservation, costs extra except on high-speed trains where it's mandatory and included
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available with advance notice
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, guide dogs travel free
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
9h 7m
Cheapest Price
$131 (€106)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Complete guide to Lyon
Things to do in Lyon
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
- Must visit
Musée des Beaux-Arts de Lyon
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
- Recommended
Lugdunum - Musée et Théâtres romains
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
- Must visit
Vieux Lyon
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
- Must visit
Place Bellecour
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
- Must visit
Parc de la Tête d'Or
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Quenelles De Brochet
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
Salade Lyonnaise
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Saucisson Brioché
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
La Mère Brazier
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
Les Halles De Lyon Paul Bocuse
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
Daniel Et Denise
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Euro
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Average meal costs
- Budget
- EUR 10-15 for a bakery lunch or kebab.
- Mid-range
- EUR 20-35 per person at a casual restaurant.
- Fine dining
- EUR 70+ per person at upscale restaurants.
- Coffee
- EUR 2.50-4 for an espresso or cappuccino.
Tipping culture
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
TCL: Itinéraires, Tickets
Get the appOfficial public transport app
Prices
- Single ticket
- 2.00 EUR
- Day pass
- 6.70 EUR
To the city center
Lyon Part-Dieu -> Bellecour, Lyon
- Distance
- 3 km
- Travel time
- 10 min
- You can use contactless bank cards on TCL ticket machines, but onboard card payment on buses or trams is not generally available.
- Validate your ticket before boarding or when entering the metro, and keep it until the end of your journey.
FAQs: Trains from Pisa to Lyon
Find answers to the most common questions about traveling from Pisa to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.
Train ticket prices from Pisa to Lyon can vary. The cheapest ticket starts at $131 (€106), while the average price is around $131 (€106).
The train from Pisa to Lyon runs once a day and takes approximately 9h 7m.
The distance by train from Pisa to Lyon is 306 miles (493 km).
The first train from Pisa to Lyon leaves at 12:25 AM.
The last train from Pisa to Lyon leaves at 8:20 PM.
There is no high speed train available from Pisa to Lyon.
There is no direct train service currently available from Pisa to Lyon.
Unfortunately, there is no night train available from Pisa to Lyon.
The train station in Pisa that goes to Lyon is Pisa Centrale, which connects to Lyon Part Dieu.
The cheapest way to get from Pisa to Lyon is by bus, with a cost of around $54 (€44).
The train journey from Pisa to Lyon offers scenic views, particularly as it passes through the picturesque landscapes of Tuscany and the rolling hills of the French countryside, providing travelers with glimpses of charming villages and natural beauty along the way.
A day trip from Pisa to Lyon is not feasible as the journey takes 9h 7m. The distance is 306 miles (493 km), and there is only 1 train per day.
In Lyon, you can explore Les Halles de Lyon Paul Bocuse, an indoor market offering gourmet food, take a river cruise on the Rhône and Saône, and discover the secret passageways of the traboules in Vieux Lyon. Attend a performance at the Opéra de Lyon or visit the Institut Lumière for cinema history. Don't miss the Basilica of Notre-Dame de Fourvière for panoramic views, Vieux Lyon for its Renaissance architecture, Parc de la Tête d'Or with its zoo and botanical garden, the Musée des Confluences, or the bustling Place Bellecour.
For a fulfilling experience in Lyon, spending 2 to 3 days is ideal. This allows you to explore key attractions such as Vieux Lyon, Basilica of Notre-Dame de Fourvière, and the Musée des Confluences, while also enjoying the city's renowned gastronomy and vibrant cultural scene.
Yes, you can take the train from Pisa to Lyon.
Since both Pisa and Lyon are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Lyon include Annecy, Saint-Étienne, Avignon, Grenoble, Perouges.
We recommend using the bus as it is the most popular way to get from Pisa to Lyon among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
France uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most transactions, especially in cities and larger establishments, but carrying some cash is advisable for small vendors, markets, and rural areas where card acceptance may be limited.
In Lyon, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, popular tourist spots, and markets. Common scams include distraction techniques and fake charity collectors. It's advisable to keep valuables secure and be wary of overly friendly strangers offering unsolicited help. Avoid unlicensed taxi services to prevent overcharging. Staying alert in busy zones ensures a safer visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Pisa to Lyon
Pisa
Lyon
The major train station for departures in Pisa is Pisa Centrale. Find all the information you need to know about services, amenities and connections at Pisa Centrale for your trip from Pisa to Lyon.
Amenities at train station
Wifi
Lockers
Parking
Dining
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Information Deskinformation
Ticket Office Hours
- Mon - Sun: 06:00 - 20:30
Wifi
- There is free Wi-Fi available at the McDonald's.
Lockers
- There is a luggage storage office near the end of Platform 1.
Dining
- McDonald's
- Panetteria Binario 1
Accessibility
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Hotel
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
Ticket Office
- Mon - Sun: 06:00 - 20:30
Information Desk
- Located just outside the station on Piazza Vittorio Emanuele II.
Public transit options for Pisa Centrale
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
The major train station for arrivals in Lyon is Lyon Part Dieu. Find all the information you need to know about services, amenities and connections at Lyon Part Dieu for your journey to Lyon from Pisa.
Amenities at train station
WifiLockersParkingDining
ATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike Rental
Car RentalInformation Deskinformation
Ticket Office Hours
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Distance to city center
1 kmWifi
- Free unlimited WiFi.
Lockers
- Luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk.
Dining
- Alto Café
- Paul
- Paul The Café
- Starbucks
- Exki
- Sushi Shop
- Carrefour
Accessibility
- Complimentary personalized care is available.
Hotel
- Radisson Blu Hotel Lyon
- Mercure Lyon Center
- ibis Styles Lyon Center
Ticket Office
- Mon - Wed: 05:00 - 20:45
- Thu - Sat: 05:00 - 21:45
- Sun: 06:45 - 21:45
Information Desk
- Located in the station's main hall.
Public transit options for Lyon Part Dieu
- Metro lines: A, B, C, D
- Tram lines: T4, K240, T3, K100
- Bus lines: 2960, C2, C3, C6, C9
- Train lines: TGV, TGV Lyria, TGV INOUI, OUIGO, TER, Intercités, Eurostar, AVE
Most popular train connections from Pisa
More options for your journey from Pisa to Lyon
Here are some other resources that might have the information you need
Most popular trains to and from Lyon and Pisa
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