- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$132
Average price
$132
Fastest journey
14 h 38 m
Average duration
14 h 38 m
Trains per day
1
Distance
493 km
The best way to find a cheap train ticket from Pisa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Lyon will cost around $132 if you buy it on the day, but the cheapest tickets can be found for only $132.
It's difficult to get from Pisa to Lyon without transferring at least 2 times.


Omio recommends booking the bus as it is the most popular option from Pisa to Lyon among Omio's users. If you are prioritising price take the train with prices starting from $2. For those with little time consider booking a flight which can get you there in 3h 38m. The ticket price range depends on the travel mode: a train costs an average of $2, and a flight costs an average of $160.
Distance: 306 miles (493 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$23 Average price Cheapest | $111 Average price | $718 Average price | $294 Average price (fuel + tolls) |
8h 37m Average total duration 8h 7m Onboard + 30m Additional time* | 11h 49m Average total duration 11h 19m Onboard + 30m Additional time* | 6h 38m Average total duration Fastest 3h 38m Onboard + 3h 0m Additional time* | 7h 32m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa to Lyon:
A train is $88 less than a bus for this route with tickets for a bus from Pisa to Lyon costing on average $111.
A train is $695 less than a flight for this route with tickets for a flight from Pisa to Lyon costing on average $718.
Other travel options to Lyon take longer:
Train takes on average 8h 7m.
Bus takes on average 11h 19m.
Tickets start at around $23 compared to roughly $294 in fuel and tolls — a saving of about $271. The journey takes 8h 7m versus 7h 32m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Pisa to Lyon trains for today, Tuesday, August 25. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 18260+ 9908+ FRECCIAROSSA 1000 9296 | 6:29 AM Pisa Centrale | 14h03 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18260+ 9928+ FRECCIAROSSA 1000 9296 | 6:29 AM Pisa Centrale | 14h03 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18260+ 9912+ FRECCIAROSSA 1000 9296 | 6:29 AM Pisa Centrale | 14h03 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18264+ 9928+ FRECCIAROSSA 1000 9296 | 6:54 AM Pisa Centrale | 13h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18266+ 9912+ FRECCIAROSSA 1000 9296 | 6:58 AM Pisa Centrale | 13h34 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18266+ 9928+ FRECCIAROSSA 1000 9296 | 6:58 AM Pisa Centrale | 13h34 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4014+ 9912+ FRECCIAROSSA 1000 9296 | 7:38 AM Pisa Centrale | 12h54 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18425+ 9928+ FRECCIAROSSA 1000 9296 | 7:44 AM Pisa Centrale | 12h48 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18425+ 9912+ FRECCIAROSSA 1000 9296 | 7:44 AM Pisa Centrale | 12h48 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18270+ 9928+ FRECCIAROSSA 1000 9296 | 7:54 AM Pisa Centrale | 12h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18270+ 9924+ FRECCIAROSSA 1000 9296 | 7:54 AM Pisa Centrale | 12h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18270+ 9912+ FRECCIAROSSA 1000 9296 | 7:54 AM Pisa Centrale | 12h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18272+ 9920+ FRECCIAROSSA 1000 9296 | 8:03 AM Pisa Centrale | 12h29 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18272+ 9928+ FRECCIAROSSA 1000 9296 | 8:03 AM Pisa Centrale | 12h29 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18272+ 9924+ FRECCIAROSSA 1000 9296 | 8:03 AM Pisa Centrale | 12h29 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4016+ 9928+ FRECCIAROSSA 1000 9296 | 8:32 AM Pisa Centrale | 12h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4016+ FRECCIAROSSA 1000 9296+ 9924 | 8:32 AM Pisa Centrale | 12h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4016+ 9920+ FRECCIAROSSA 1000 9296 | 8:32 AM Pisa Centrale | 12h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18489+ 9928+ FRECCIAROSSA 1000 9296 | 8:50 AM Pisa Centrale | 11h42 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18489+ 9924+ FRECCIAROSSA 1000 9296 | 8:50 AM Pisa Centrale | 11h42 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4018+ 9920+ FRECCIAROSSA 1000 9296 | 9:09 AM Pisa Centrale | 11h23 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4018+ 9928+ FRECCIAROSSA 1000 9296 | 9:09 AM Pisa Centrale | 11h23 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4018+ FRECCIAROSSA 1000 9296+ 9924 | 9:09 AM Pisa Centrale | 11h23 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4020+ 9924+ FRECCIAROSSA 1000 9296 | 9:32 AM Pisa Centrale | 11h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4020+ 9928+ FRECCIAROSSA 1000 9296 | 9:32 AM Pisa Centrale | 11h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4020+ 9920+ FRECCIAROSSA 1000 9296 | 9:32 AM Pisa Centrale | 11h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18282+ 9920+ FRECCIAROSSA 1000 9296 | 9:54 AM Pisa Centrale | 10h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18282+ 9924+ FRECCIAROSSA 1000 9296 | 9:54 AM Pisa Centrale | 10h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18282+ 9928+ FRECCIAROSSA 1000 9296 | 9:54 AM Pisa Centrale | 10h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18286+ 9924+ FRECCIAROSSA 1000 9296 | 10:01 AM Pisa Centrale | 10h31 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18286+ 9928+ FRECCIAROSSA 1000 9296 | 10:01 AM Pisa Centrale | 10h31 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4026+ FRECCIAROSSA 1000 9296+ 9928 | 10:32 AM Pisa Centrale | 10h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4026+ 9924+ FRECCIAROSSA 1000 9296 | 10:32 AM Pisa Centrale | 10h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18409+ 9924+ FRECCIAROSSA 1000 9296 | 10:54 AM Pisa Centrale | 9h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18409+ 9928+ FRECCIAROSSA 1000 9296 | 10:54 AM Pisa Centrale | 9h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 4028+ 9928+ FRECCIAROSSA 1000 9296 | 11:09 AM Pisa Centrale | 9h23 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 4028+ 9924+ FRECCIAROSSA 1000 9296 | 11:09 AM Pisa Centrale | 9h23 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale Veloce 4030+ 9928+ FRECCIAROSSA 1000 9296 | 11:30 AM Pisa Centrale | 9h02 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 18288+ 9928+ FRECCIAROSSA 1000 9296 | 11:54 AM Pisa Centrale | 8h38 | 8:32 PM Lyon Part Dieu | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa to Lyon run on average 38 times per day, taking around 8h 7m. Cheap train tickets for this journey start at $2 if you book in advance.
The earliest train runs at 00:25, the last at 20:20. The fastest train covers the 306 miles (493 km) distance in 7h 16m.
Distance 306 miles (493 km) |
Average train duration 8h 7m |
Cheapest ticket price $2 |
Trains per day 38 |
Fastest train 7h 16m |
First train 12:25 AM |
Last train 8:20 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Fri |
Best time to book 4 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Pisa to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Pisa to Lyon trains use the Pisa Centrale to Lyon Part Dieu station pair. Use this guide to compare Pisa and Lyon train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
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