Pisa to Lyon train with Trenitalia

Sat, Jan 10
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Trenitalia
Regionale
Deutsche Bahn
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Italo
1,000+ travel companies
Trenitalia
Regionale
Deutsche Bahn
iryo
Italo
1,000+ travel companies
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Travel Information

Compare train, bus, and flight for Pisa to Lyon

Omio recommends booking the bus as it is the most popular option from Pisa to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €45. For those with little time consider booking a train which can get you there in 7h 47m. The ticket price range depends on the travel mode: a bus costs an average of €45, and a flight costs an average of €159.

Distance: 306 miles (493 km)

Compare train with

Train
Most popular
Bus
Flight

€126

Average price

€85

Average price

Cheapest

€703

Average price

8h 17m

Average total duration

Fastest

7h 47m

Onboard

+

30m

Additional time*

11h 28m

Average total duration

10h 58m

Onboard

+

30m

Additional time*

20h 35m

Average total duration

17h 35m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Pisa to Lyon by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Pisa to Lyon trains with Omio?

Trenitalia as well as Regionale offer trains services from Pisa to Lyon. Omio is an official ticket reseller for all your travel options from Pisa to Lyon.

Why book with Omio vs Trenitalia?

  • Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Regionale to find the best option for your trip from Pisa to Lyon.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Lyon.

Why book with Omio over Trainline and Rail Europe?

Multiple modes of transport
  • Multiple travel company options: While Trenitalia tickets can be bought on Trenitalia's website or third party sellers, Omio allows you to compare with the likes of Regionale to help you choose the right option for your journey from Pisa to Lyon.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Lyon.

Journey information

Overview: Train from Pisa to Lyon

ItalyItaly
FranceFrance
Icon of train

Trains from Pisa to Lyon run on average 1 times per day, taking around 7h 47m. Cheap train tickets for this journey start at $156 (€126) but you can travel from only $56 (€45) by bus.

The earliest train runs at 00:25, the last at 20:05. The fastest train covers the 306 miles (493 km) distance in 8h 23m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $56 (€45)
Distance
306 miles (493 km)
Average train duration
7h 47m
Cheapest ticket price
$156 (€126)
Trains per day
1
Fastest train
8h 23m
First train
00:25
Last train
20:05
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $56 (€45)

Train companies: Trenitalia, Regionale from Pisa to Lyon trainsTrenitalia, Regionale trains will get you between Pisa and Lyon from $56 (€45). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Trenitalia

About
Trenitalia is not only Italy's national railroad company but also the country's largest train operator. Trenitalia’s fleet of trains ncludes the high-speed Frecciarossa, Frecciargento and Frecciabianca trains as well as intercity, regional and night trains. Bathrooms and WiFi access are standard on long-distance routes. In most cases, the trains also provide barrier-free access. Trenitalia offers different tickets, which vary in price and flexibility: Base, Economy, Super Economy and Ordinaria. You can even use Trenitalia discount cards on Omio. Make sure to look out for the latest offers from Trenitalia on Omio to score special deals!
Luggage & cancellation policy
Luggage included
2 pieces of hand luggage per passenger included in ticket price
Luggage storage
Overhead racks, luggage areas at end of carriages, and spaces between seat backs
Cancellation Policy
Cancellation policies vary by ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car on high-speed trains, trolley service with snacks and beverages, vending machines on some trains
Seat reservation
Optional seat reservation, costs extra except on high-speed trains where it's mandatory and included
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, and assistance service available with advance notice
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, guide dogs travel free
Quiet zone

Regionale

About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
8h 23m
Cheapest Price
$155 (€125)
Regionale frequency
1 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone

FAQs: Trains from Pisa to Lyon

Find answers to the most common questions about traveling from Pisa to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

FAQs
The distance by train from Pisa to Lyon is 306 miles (493 km).
For a fulfilling experience in Lyon, spending 2 to 3 days is ideal. This allows you to explore key attractions such as Vieux Lyon, Basilica of Notre-Dame de Fourvière, and the Musée des Confluences, while also enjoying the city's renowned gastronomy and vibrant cultural scene.
The train from Pisa to Lyon runs once a day and takes approximately 8h 23m.
The first train from Pisa to Lyon leaves at 12:25 AM.
In Lyon, you can explore Les Halles de Lyon Paul Bocuse, an indoor market offering gourmet food, take a river cruise on the Rhône and Saône, and discover the secret passageways of the traboules in Vieux Lyon. Attend a performance at the Opéra de Lyon or visit the Institut Lumière for cinema history. Don't miss the Basilica of Notre-Dame de Fourvière for panoramic views, Vieux Lyon for its Renaissance architecture, Parc de la Tête d'Or with its zoo and botanical garden, the Musée des Confluences, or the bustling Place Bellecour.
There is no high speed train available from Pisa to Lyon.
The last train from Pisa to Lyon leaves at 8:05 PM.
A day trip from Pisa to Lyon is not feasible as the journey takes 8h 23m. The distance is 306 miles (493 km), and there is only 1 train per day.
There is no direct train service currently available from Pisa to Lyon.
The train journey from Pisa to Lyon offers scenic views, particularly as it passes through the picturesque landscapes of Tuscany and the rolling hills of the French countryside, providing travelers with glimpses of charming villages and natural beauty along the way.
Train ticket prices from Pisa to Lyon can vary. The cheapest ticket starts at $156 (€126), while the average price is around $156 (€126).
Yes, you can take the train from Pisa to Lyon.
The cheapest way to get from Pisa to Lyon is by bus, with a cost of around $56 (€45).
The train station in Pisa that goes to Lyon is Pisa Centrale, which connects to Lyon Part Dieu.
Unfortunately, there is no night train available from Pisa to Lyon.

popular train stations

Popular train stations from Pisa to Lyon

Pisa
Lyon
The major train station for departures in Pisa is Pisa Centrale. Find all the information you need to know about services, amenities and connections at Pisa Centrale for your trip from Pisa to Lyon.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Information DeskInformation Desk
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 06:00 - 20:30
Wifi
Wifi
  • There is free Wi-Fi available at the McDonald's.
Lockers
Lockers
  • There is a luggage storage office near the end of Platform 1.
Dining
Dining
  • McDonald's
  • Panetteria Binario 1
Accessibility
Accessibility
  • Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Hotel
Hotel
  • Hotel NH Pisa
  • Hotel La Pace
  • Hotel Maria
Ticket Office
Ticket Office
  • Mon - Sun: 06:00 - 20:30
Information Desk
Information Desk
  • Located just outside the station on Piazza Vittorio Emanuele II.
Public transit options for Pisa Centrale
  • Bus lines: 1
  • Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN

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