4.9
4.6
Travel Information
Compare train, bus, and flight for Pisa to Lyon
Omio recommends booking the bus as it is the most popular option from Pisa to Lyon among Omio's users. If you are prioritising price, take the train, with an average ticket price of $18 For those with little time, consider booking a flight, which has an average total journey time of 5h 37m. Average ticket prices depend on the travel mode: a train costs an average of $18, while a flight costs an average of $607.
Distance: 306 miles (493 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$102 Average price | $18 Average price Cheapest | $607 Average price | $282 Average price (fuel + tolls) |
11h 55m Average total duration 11h 25m Onboard + 30m Additional time* | 8h 33m Average total duration 8h 3m Onboard + 30m Additional time* | 5h 37m Average total duration Fastest 3h 37m Onboard + 2h 0m Additional time* | 7h 32m Average total duration (door-to-door) |
 Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Compare ways to travel from Pisa to Lyon
Compare the available ways to get from Pisa to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Pisa to Lyon:
A train is $85 less than a bus for this route with tickets for a bus from Pisa to Lyon costing on average $102.
A train is $590 less than a flight for this route with tickets for a flight from Pisa to Lyon costing on average $607.
Other travel options to Lyon take longer:
Train takes on average 8h 33m.
Bus takes on average 11h 55m.
Tickets start at around $102 compared to roughly $282 in fuel and tolls — a saving of about $181. The journey takes 11h 25m versus 7h 32m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Pisa to Lyon
How to get from Pisa to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Lyon is by taking a bus because it’s the best combination of price and speed.
- FlixBus · FlixBus
5:10 PM 13h20 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $95 1 One-way 1 transfer
Cheapest
- FlixBus · FlixBus
5:10 PM 13h20 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $95 1 One-way 1 transfer
Fastest
Regionale 18288+
9928+FRECCIAROSSA 1000 929611:54 AM 8h38 Pisa Centrale 8:32 PM Lyon Part Dieu $167 1 One-way 2 transfers
Other options
- Regionale 4028+9924+FRECCIAROSSA 1000 9296
11:09 AM 9h23 Pisa Centrale 8:32 PM Lyon Part Dieu $163 1 One-way 2 transfers - Regionale 18409+9924+FRECCIAROSSA 1000 9296
10:54 AM 9h38 Pisa Centrale 8:32 PM Lyon Part Dieu $163 1 One-way 2 transfers - Regionale Veloce 4026+9924+FRECCIAROSSA 1000 9296
10:32 AM 10h00 Pisa Centrale 8:32 PM Lyon Part Dieu $163 1 One-way 2 transfers
- FlixBus · FlixBus
6:10 PM 14h35 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $95 1 One-way 1 transfer - FlixBus · FlixBus
7:15 AM 16h40 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 11:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $104 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Lyon.
This is compared to other travel options from Pisa to Lyon:
A train is $85 less than a bus for this route with tickets for a bus from Pisa to Lyon costing on average $102.
A train is $590 less than a flight for this route with tickets for a flight from Pisa to Lyon costing on average $607.
Other travel options to Lyon take longer:
Train takes on average 8h 33m.
Bus takes on average 11h 55m.
- Around 34 trains per day.
- Around 9 flights per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between Pisa and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Pisa Centrale and arrive in Lyon Part Dieu.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with Trenitalia, Intercity, SNCF | TGV INOUI, Frecciarossa, Intercity Notte to go to Lyon by train.
- Travel with Transavia France, Air Dolomiti, British Airways, Austrian Airlines, Eurowings to go to Lyon by flight.
- Travel with FlixBus to go to Lyon by bus.
Travelling from Pisa to Lyon: related information
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