- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price
€26
Average price
€50
Fastest journey
2 h 52 m
Average duration
2 h 54 m
Trains per day
44
Distance
265 km
The best way to find a cheap train ticket from Pisa to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Rome will cost around €50 if you buy it on the day, but the cheapest tickets can be found for only €26.
Of the 44 trains that leave Pisa for Rome on Fri, Aug 14, 26 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Aug 14 the direct trains cover the 265 km distance in an average of 2 h 54 m but if you time it right, some trains will get you there in just 2 h 52 m .
On Fri, Aug 14 the slowest trains will take 2 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 4131
Regionale Veloce 4137
Regionale Veloce 4133
Regionale Veloce 4135
Regionale Veloce 4139
Intercity 583
FRECCIARGENTO 8583
FRECCIARGENTO 8591
FRECCIARGENTO 8551
FRECCIABIANCA 8601Omio recommends booking the train as it is the most popular option from Pisa to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a train which can get you there in 3h 37m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of €13, and a train costs an average of €21.
Distance: 164 miles (265 km)
Most popular Train | Bus | Driving |
|---|---|---|
€28 Average price | €21 Average price Cheapest | €68 Average price (fuel + tolls) |
4h 7m Average total duration Fastest 3h 37m Onboard + 30m Additional time* | 5h 2m Average total duration 4h 32m Onboard + 30m Additional time* | 3h 50m Average total duration (door-to-door) |
0.1 - 0.2kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Rome:
A bus is €6 less than a train for this route with tickets for a train from Pisa to Rome costing on average €28.
Other travel options to Rome take longer:
Train takes on average 3h 37m.
Bus takes on average 4h 32m.
The journey is about 13m faster (3h 37m by train vs 3h 50m by car) and roughly €40 cheaper once you factor in fuel and tolls (€28 vs €68). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with Frecciabianca, Regionale, Intercity, Frecciargento, Frecciarossa, Intercity Notte.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Pisa to Rome trains for today, Thursday, August 13. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 4032+ FRECCIAROSSA 9415 | 12:32 PM Pisa Centrale | 3h23 | 3:55 PM Rome Termini | 1 transfer | |
Regionale Veloce 4133 | 1:43 PM Pisa Centrale | 4h05 | 5:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4133 | 1:43 PM Pisa Centrale | 3h39 | 5:22 PM Rome S. Pietro | 0 transfersDirect | |
FRECCIABIANCA 8613 | 2:07 PM Pisa Centrale | 2h56 | 5:03 PM Rome Termini | 0 transfersDirect | |
Intercity 511 | 2:53 PM Pisa Centrale | 3h10 | 6:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4042+ FRECCIAROSSA 9425 | 3:32 PM Pisa Centrale | 3h23 | 6:55 PM Rome Termini | 1 transfer | |
Regionale Veloce 4135 | 3:45 PM Pisa Centrale | 4h03 | 7:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4135 | 3:45 PM Pisa Centrale | 3h37 | 7:22 PM Rome S. Pietro | 0 transfersDirect | |
Regionale 18308+ Intercity 597 | 4:01 PM Pisa Centrale | 5h06 | 9:07 PM Rome Tiburtina | 1 transfer | |
Regionale Veloce 4044+ FRECCIAROSSA 9427 | 4:32 PM Pisa Centrale | 3h23 | 7:55 PM Rome Termini | 1 transfer | |
FRECCIABIANCA 8619 | 5:07 PM Pisa Centrale | 2h56 | 8:03 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4048+ FRECCIAROSSA 9431 | 5:32 PM Pisa Centrale | 3h23 | 8:55 PM Rome Termini | 1 transfer | |
Regionale Veloce 4137 | 5:45 PM Pisa Centrale | 4h03 | 9:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4137 | 5:45 PM Pisa Centrale | 3h37 | 9:22 PM Rome S. Pietro | 0 transfersDirect | |
Regionale Veloce 4052+ FRECCIAROSSA 9433 | 6:32 PM Pisa Centrale | 3h28 | 10:00 PM Rome Termini | 1 transfer | |
FRECCIAROSSA 8623 | 7:11 PM Pisa Centrale | 3h07 | 10:18 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4058+ FRECCIAROSSA 9435 | 7:32 PM Pisa Centrale | 3h18 | 10:50 PM Rome Termini | 1 transfer | |
Regionale Veloce 4139 | 7:45 PM Pisa Centrale | 4h03 | 11:48 PM Rome Termini | 0 transfersDirect | |
InterCityNotte 795 | 8:11 PM Pisa Centrale | 3h12 | 11:23 PM Rome Ostiense | 0 transfersDirect | |
FRECCIARGENTO 8591 | 8:38 PM Pisa Centrale | 2h53 | 11:31 PM Rome Termini | 0 transfersDirect | |
Regionale 18407+ FRECCIAROSSA 9567 | 8:42 PM Pisa Centrale | 3h42 | 12:24 AM Rome Termini | 1 transfer | |
| Friday, August 14 | |||||
InterCityNotte 899 | 2:21 AM Pisa Centrale | 3h22 | 5:43 AM Rome Ostiense | 0 transfersDirect | |
Regionale 18250+ Intercity 581 | 4:15 AM Pisa Centrale | 4h20 | 8:35 AM Rome Termini | 1 transfer | |
Regionale 18252+ FRECCIAROSSA 9591 | 5:19 AM Pisa Centrale | 3h46 | 9:05 AM Rome Termini | 1 transfer | |
Regionale Veloce 4125 | 5:45 AM Pisa Centrale | 4h03 | 9:48 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4125 | 5:45 AM Pisa Centrale | 3h37 | 9:22 AM Rome S. Pietro | 0 transfersDirect | |
Regionale 18260+ FRECCIAROSSA 9401 | 6:29 AM Pisa Centrale | 3h18 | 9:47 AM Rome Tiburtina | 1 transfer | |
Intercity 501 | 6:47 AM Pisa Centrale | 3h28 | 10:15 AM Rome Ostiense | 0 transfersDirect | |
FRECCIABIANCA 8601 | 7:07 AM Pisa Centrale | 2h56 | 10:03 AM Rome Termini | 0 transfersDirect | |
People Mover PM020 · Regionale Veloce 4129 | 7:30 AM Pisa | 3h54 | 11:24 AM Rome S. Pietro | 1 transfer | |
FRECCIARGENTO 8583 | 7:33 AM Pisa Centrale | 2h52 | 10:25 AM Rome Termini | 0 transfersDirect | |
Regionale 18425+ FRECCIAROSSA 9515 | 7:44 AM Pisa Centrale | 3h31 | 11:15 AM Rome Termini | 1 transfer | |
Regionale Veloce 4129 | 7:45 AM Pisa Centrale | 4h03 | 11:48 AM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4016+ FRECCIAROSSA 9405 | 8:32 AM Pisa Centrale | 3h17 | 11:49 AM Rome Termini | 1 transfer | |
FRECCIABIANCA 8605 | 9:07 AM Pisa Centrale | 3h11 | 12:18 PM Rome Termini | 0 transfersDirect | |
FRECCIARGENTO 8551 | 9:15 AM Pisa Centrale | 2h55 | 12:10 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4020+ FRECCIAROSSA 9409 | 9:32 AM Pisa Centrale | 3h18 | 12:50 PM Rome Termini | 1 transfer | |
Regionale 18282+ FRECCIAROSSA 8503 | 9:54 AM Pisa Centrale | 3h41 | 1:35 PM Rome Termini | 1 transfer | |
Intercity 583 | 10:57 AM Pisa Centrale | 2h52 | 1:49 PM Rome Ostiense | 0 transfersDirect | |
Intercity 505 | 11:11 AM Pisa Centrale | 3h22 | 2:33 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4030+ FRECCIAROSSA 9413 | 11:30 AM Pisa Centrale | 3h15 | 2:45 PM Rome Termini | 1 transfer | |
Regionale Veloce 4131 | 11:45 AM Pisa Centrale | 4h03 | 3:48 PM Rome Termini | 0 transfersDirect | |
Regionale Veloce 4131 | 11:45 AM Pisa Centrale | 3h37 | 3:22 PM Rome S. Pietro | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
By Lara Fiorani

Regional, intercity, or high-speed? Direct or indirect? Traveling from Pisa to Rome by train, you have plenty of options. Here's how to plan the quintessential Tuscan train adventure.

An image of Pisa Centrale station
The distance between Pisa Centrale and Rome Termini is 165 miles (265 km). Direct high-speed and Regionale trains follow the Livorno–Civitavecchia coastal route. Indirect services via Florence (a combination of Regionale and high-speed) travel inland through Tuscany.
South of Florence, you’ll ride through a quintessential Tuscan landscape of rolling hills, cypresses, olive trees, sunflowers and wheat fields. Make sure you get a window seat!
When I booked, the direct high-speed Frecciabianca seats were full price. However, the Trenitalia Florence-Rome high-speed route was on sale. When you add up the travel times of a direct Regionale and an indirect journey via Florence, there isn't a huge difference.
Buses are cheaper, but they take over 5 hours, arriving at Roma Tiburtina instead of Termini.
Pisa Centrale station is a 25-minute walk from the Leaning Tower. Inside the station, eating options are limited. I was glad I had stopped for coffee and a pastry en route.
Despite the small ticketing hall, Pisa Centrale has 16 platforms. They are connected by a tunnel, and there are lifts if you have heavy luggage.
The station was busy in the morning. It took me a few minutes to find my platform. Arrive at least 20 minutes early.
After Pisa, Roma Termini felt more like a busy shopping mall than a station.
I did not linger, other than for a quick espresso in the coffee shop by the entrance. With views of the Roman walls, it was a perfect introduction to the wonders of the city!
With a metro station and many buses, just across from the roofed taxi rank, public transport is plentiful.
The Pisa-Rome route is served by 18 direct high-speed Trenitalia Frecciabianca trains. The average journey is 2 hours and 45 minutes. Slower Regionale trains connect Pisa and Rome in 4 hours, departing every couple of hours.
Traveling with a connection? Both Trenitalia and Italo serve the high-speed route between Florence and Rome, with trains every 10 to 15 minutes. The trip takes about 1 hour and 30 minutes. The Regionale from Pisa to Florence takes roughly 1 hour and 20 minutes.
In Pisa, I reached my platform through the underground tunnel, boarded the train, and found an empty seat. In Florence, I went through ticket barriers before reaching the platform. Be sure to keep your documents readily available, as they may check your passport or e-ticket again during the journey.
The Regionale trains only have Standard Class. They are a clean, efficient, no-frills option. The only downside is the Wi-Fi, which is often slow and patchy. Trenitalia’s Premium Class has leather seats, and the service includes a complimentary snack and drink. There is free Wi-Fi, and plenty of room for luggage.
Regionale trains have fixed prices, and my Pisa to Rome fare was €25. A great feature of Omio is that you can play around with different classes and flexibility levels. I realised that a Premier Class Frecciarossa from Florence to Rome was also €25. Sure, the Regionale from Pisa to Florence would cost another €11, but how could I say no to the idea of a stopover in Florence?
| Item | Cost (eur) |
|---|---|
| Ticket price | €25 |
| Food & drinks | €3.5 |
| Travel to departure station | €0 |
| Travel from arrival station | €1.5 |
| Total | € 30 |
Pisa to Rome is a train trip you will treasure for years to come. You can enjoy postcard-perfect images of Tuscany from the comfort of your seat. Remember to book your Pisa to Rome train tickets on Omio early to get the best deal on your fare.
Trains from Pisa to Rome run on average 45 times per day, taking around 3h 37m. Cheap train tickets for this journey start at €21 but you can travel from only €13 by bus.
There are 18 trains per day. The earliest train runs at 00:01, the last at 23:57. The fastest train covers the 164 miles (265 km) distance in 2h 23m.
Distance 164 miles (265 km) |
Average train duration 3h 37m |
Cheapest ticket price €21 |
Trains per day 45 |
Direct trains 18 |
Fastest train 2h 23m |
First train 12:01 AM |
Last train 11:57 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 63 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Roma Termini -> Piazza Di Spagna, Rome
Traveling between Pisa and Rome is a delightful experience, thanks to the efficient train connections available. You can choose from several providers including Frecciabianca, Regionale, and Intercity. These trains offer comfortable seating and scenic views of the Italian countryside as you journey through this beautiful region. Whether you're heading for a day trip or an extended stay in the capital city, you'll find convenient schedules that make your travel seamless.
Traveling from Pisa to Rome takes approximately 2 hours and 18 minutes. There are a total of 11 connections available each day, all of which are direct services. Passengers can depart from either Pisa Centrale or Pisa San Rossore stations and arrive at one of several destinations in Rome, including Roma Tiburtina, Roma Ostiense, Roma Termini, Roma San Pietro, and Roma Trastevere.
The first daily train from Pisa to Rome departs at 05:07, allowing early travelers to start their journey. The last train of the day leaves at 19:47, providing a convenient option for those wishing to explore the sights of both cities before returning in the evening.
The cheapest ticket price for the train connection from Pisa to Rome is €20. The average ticket price typically hovers around €29, making it a convenient and affordable option for travelers looking to explore these two beautiful Italian cities.
Welcome to the Colosseum, an iconic symbol of ancient Rome that dates back to AD 70-80. This monumental amphitheater once hosted gladiatorial contests and public spectacles, drawing crowds of up to 50,000 spectators who marveled at its architectural grandeur. What makes the Colosseum truly unique is its innovative design featuring a complex system of vaults and arches that has inspired countless structures throughout history.
As we step into St. Peter's Basilica, you'll find yourself in one of the holiest sites in Christianity and a masterpiece of Renaissance architecture completed in 1626. The basilica stands as a testament to faith and artistry with Michelangelo’s breathtaking dome soaring above you while housing remarkable works like Bernini's Baldachin. Its significance extends beyond religion; it represents centuries of artistic achievement and remains a pilgrimage destination for millions around the world.
Finally, let’s explore the Pantheon—an architectural marvel built around AD 126 that boasts an impressive domed roof with an oculus allowing natural light to illuminate its stunning interior. Originally constructed as a temple dedicated to all gods, this structure exemplifies Roman engineering prowess through its harmonious proportions and enduring beauty over nearly two millennia. Unique among ancient buildings for being continuously used since antiquity, it now serves as both church and tomb—a living piece of history inviting reflection on time itself.
Find answers to the most common questions about traveling from Pisa to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Pisa to Rome trains use the Pisa Centrale to Roma Termini station pair, with some services arriving at Roma Tiburtina. Use this guide to compare Pisa and Rome train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Pisa, Aeroporto Galilei Di Pisa is 1 km from Pisa city centre. Check local transport options before travel.
Pisa, Aeroporto Galilei Di Pisa has practical services for this route, including Accessibility.
Accessibility facilities are available at Pisa, Aeroporto Galilei Di Pisa.
Pisa San Rossore is 1 km from Pisa city centre. Public transport options include:
Pisa San Rossore has practical services for this route, including Parking, Dining, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Bike Rental.
Food options include: Ristorante pizzeria, SushiKing, Ristorante Cinese Oriente
The ticket office is open 24/7.
Available at Pisa San Rossore: Parking, WC.
Available at Pisa San Rossore: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa San Rossore: Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
Nearby hotels include Rosso di Sera Relais Tuscany, Le Cascine, Camping Village Torre Pendente.
Roma Termini is 1 km from Rome city centre. Public transport options include:
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Available at Roma Termini: Parking, Taxis, WC.
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ramen Bar Akira, Eataly Roma
Free. ATMs are available in the train station.
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Available at Roma Ostiense: Parking, Taxis, WC.
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.
Roma San Pietro is 2 km from Rome city centre. Public transport options include:
Roma San Pietro has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food options include: Ristorante La Vittoria, Osteria dei Pontefici
Free.
Ticket office support is available at Roma San Pietro. Information desks are located in the main hall.
Luggage storage is available at Roma San Pietro. Lost and found is available at the station.
Available at Roma San Pietro: Parking, Taxis, WC.
Available at Roma San Pietro: Bike Parking.
Accessibility facilities are available at Roma San Pietro: Elevators, ramps, restrooms.
Nearby hotels include Starhotels Michelangelo Rome, Hotel San Pietro, Hotel Paolo II.
Here are some other resources that might have the information you need