The cheapest and fastest trains from Pisa to Brussels
Cheapest price
$370
Average price
$370
Fastest journey
20 h 38 m
Average duration
20 h 38 m
Trains per day
1
Distance
914 km
The best way to find a cheap train ticket from Pisa to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brussels will cost around $370 if you buy it on the day, but the cheapest tickets can be found for only $370.
It's difficult to get from Pisa to Brussels without transferring at least 4 times.


Travel Information
Compare train, bus, and flight for Pisa to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from €25. For those with little time consider booking a flight which can get you there in 2h 33m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of €25, and a train costs an average of €300.
Distance: 567 miles (914 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€300 Average price | €94 Average price Cheapest | €117 Average price |
21h 8m Average total duration 20h 38m Onboard + 30m Additional time* | 5h 33m Average total duration Fastest 2h 33m Onboard + 3h 0m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* |
- CO2 emissions | 2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Brussels train times
The table below shows live departures for Pisa to Brussels trains for tomorrow, Wednesday, January 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:09 AM Pisa | 20h38 | 7:47 AM Brussels | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 21
Jan 22
Jan 23
Jan 24
Jan 25
Jan 26
Jan 27
Why should you book Pisa to Brussels trains with Omio?
Regionale operates all train services from Pisa to Brussels. Omio is the only official third party seller for Regionale tickets.
Why book with Omio vs Regionale?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Regionale with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Brussels.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Regionale tickets can only be bought on Omio or Regionale's website as Omio is the only official third party seller for Regionale tickets. Trainline, RailEurope, and Rail.Ninja do not sell Regionale tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Brussels.
Journey information
Overview: Train from Pisa to Brussels
Train Ticket Prices
- Budget Options: Train tickets from Pisa to Brussels start from as low as $375 (€300) if booked well in advance.
- Standard Fares: Typically, trains cost $375 (€300) depending on the train type and class.
Journey Duration & Frequency
- On average there are 1 daily trains from Pisa to Brussels with 0 direct service.
- The fastest trains can take as little as 20h 38m but the average duration is 20h 38m
Train Operators
- Travel from Pisa to Brussels with Regionale
- The most booked train company for this route on Omio is Regionale.
Stations & Schedule
- First train typically departs at 12:32 AM and the last at 08:05 PM
Distance 567 miles (914 km) |
Average train duration 20h 38m |
Cheapest ticket price $375 (€300) |
Trains per day 1 |
Fastest train 20h 38m |
First train 00:32 |
Last train 20:05 |
Train companies: Regionale from Pisa to Brussels trainsRegionale trains will get you between Pisa and Brussels from $31 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
FAQs: Trains from Pisa to Brussels
Find answers to the most common questions about traveling from Pisa to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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