Travel Information
Compare train, bus, and flight for Pisa to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $76. For those with little time consider booking a flight which can get you there in 2h 30m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $76, and a train costs an average of $370.
Distance: 567 miles (914 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
$370 Average price | $129 Average price | $127 Average price Cheapest |
21h 8m Average total duration 20h 38m Onboard + 30m Additional time* | 5h 30m Average total duration Fastest 2h 30m Onboard + 3h 0m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* |
- CO2 emissions | 2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Pisa to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Pisa to Brussels
Trains from Pisa to Brussels run on average 1 times per day, taking around 20h 38m. Cheap train tickets for this journey start at $370 (€295) but you can travel from only $21 (€17) by flight.
The earliest train runs at 00:32, the last at 20:05. The fastest train covers the 567 miles (914 km) distance in 20h 38m.
Distance 567 miles (914 km) |
Average train duration 20h 38m |
Cheapest ticket price $370 (€295) |
Trains per day 1 |
Fastest train 20h 38m |
First train 12:32 AM |
Last train 8:05 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Fri |
Best time to book 49 days |
Train companies: Regionale from Pisa to Brussels trainsRegionale trains will get you between Pisa and Brussels from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
FAQs: Trains from Pisa to Brussels
Find answers to the most common questions about traveling from Pisa to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most popular train connections from Pisa
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