- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Sep 05
$412
Average ticket price on Sep 05
$412
Fastest journey on Sep 05
13 h 9 m
Average journey duration on Sep 05
18 h 27 m
Trains on Sep 05
2
Distance
914 km
The best way to find a cheap train ticket from Pisa to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brussels will cost around $412 if you buy it on the day, but the cheapest tickets can be found for only $412.
It's difficult to get from Pisa to Brussels without transferring at least 3 times.




Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price, take the flight, with an average ticket price of $82 For those with little time, consider booking a flight, which has an average total journey time of 4h 31m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.3kg. Average ticket prices depend on the travel mode: a flight costs an average of $82, while a train costs an average of $375.
Distance: 567 miles (914 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$375 Average price | $82 Average price Cheapest | $131 Average price | $356 Average price (fuel + tolls) |
19h 50m Average total duration 19h 20m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 2h 31m Onboard + 2h 0m Additional time* | 21h 49m Average total duration 21h 19m Onboard + 30m Additional time* | 12h 39m Average total duration (door-to-door) |
- CO2 emissions | 2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Brussels:
A flight is $49 (€40) less than a bus for this route with tickets for a bus from Pisa to Brussels costing on average $131 (€106).
A flight is $293 (€237) less than a train for this route with tickets for a train from Pisa to Brussels costing on average $375 (€303).
Other travel options to Brussels take longer:
Train takes on average 19h 20m.
Bus takes on average 21h 19m.
Tickets start at around $375 (€303) compared to roughly $356 (€287) in fuel and tolls — a saving of about $-19.38 (€-15.66). The journey takes 19h 20m versus 12h 39m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Pisa to Brussels trains for tomorrow, Saturday, September 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:47 AM Pisa | 13h09 | 8:56 PM Brussels | 3 transfers | |
![]() | 11:25 AM Pisa | 23h44 | 11:09 AM Brussels | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa to Brussels run on average 2 times per day, taking around 19h 20m. Cheap train tickets for this journey start at $282 (€228) but you can travel from only $27 (€22) by flight.
The earliest train runs at 01:51, the last at 20:05. The fastest train covers the 567 miles (914 km) distance in 13h 9m.
Distance 567 miles (914 km) |
Average train duration 19h 20m |
Cheapest ticket price $282 (€228) |
Trains per day 2 |
Fastest train 13h 9m |
First train 1:51 AM |
Last train 8:05 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Pisa to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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