- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
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Travel Information
Compare train, bus, and flight for Pisa to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $23. For those with little time consider booking a flight which can get you there in 2h 31m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of $23, and a train costs an average of $277.
Distance: 567 miles (914 km)
Compare train with
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$368 Average price | $132 Average price Cheapest | $134 Average price | $346 Average price (fuel + tolls) |
19h 50m Average total duration 19h 20m Onboard + 30m Additional time* | 5h 31m Average total duration Fastest 2h 31m Onboard + 3h 0m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* | 12h 39m Average total duration (door-to-door) |
- CO2 emissions | 2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Pisa to Brussels is a flight with an average price of $132 (€109).
This is compared to other travel options from Pisa to Brussels:
A flight is $2 (€2) less than a bus for this route with tickets for a bus from Pisa to Brussels costing on average $134 (€110).
A flight is $236 (€194) less than a train for this route with tickets for a train from Pisa to Brussels costing on average $368 (€303).
The fastest way to travel from Pisa to Brussels is by flight with an average journey time of 2h 31m.
Other travel options to Brussels take longer:
Train takes on average 19h 20m.
Bus takes on average 20h 58m.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Brussels including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Pisa to Brussels among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $368 (€303) compared to roughly $346 (€285) in fuel and tolls — a saving of about $-22.12 (€-18.19). The journey takes 19h 20m versus 12h 39m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare prices and tickets Pisa to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Pisa to Brussels
Italy
Belgium
Trains from Pisa to Brussels run on average 2 times per day, taking around 19h 20m. Cheap train tickets for this journey start at $277 (€228) but you can travel from only $23 (€19) by flight.
The earliest train runs at 01:51, the last at 20:05. The fastest train covers the 567 miles (914 km) distance in 13h 9m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $23 (€19)
Distance 567 miles (914 km) |
Average train duration 19h 20m |
Cheapest ticket price $277 (€228) |
Trains per day 2 |
Fastest train 13h 9m |
First train 1:51 AM |
Last train 8:05 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $23 (€19)
Train companies: Regionale from Pisa to Brussels trainsRegionale trains will get you between Pisa and Brussels from $23 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
13h 9m
Cheapest Price
$277 (€228)
Regionale frequency
2 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Complete guide to Brussels
Things to do in Brussels
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
- Must visit
Magritte Museum
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
- Must visit
Comics Art Museum
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
- Must visit
Grand Place
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
- Must visit
Parc du Cinquantenaire
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
- Must visit
Mont des Arts
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Moules-Frites
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
- Vegetarian
- Gluten-free
Frites
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
Carbonnade Flamande
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Bozar Restaurant
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Brasserie La Paix
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Maison Dandoy
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Euro (€)
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Average meal costs
- Budget
- €8-15 for fast food or casual takeaway.
- Mid-range
- €20-35 per person for a standard restaurant meal.
- Fine dining
- €70+ per person for upscale restaurants.
- Coffee
- €3-5 for cappuccino or latte.
Tipping culture
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
STIB-MIVB
Get the appOfficial public transport app
Prices
- Single ticket
- €2.50
- Day pass
- €8.40
To the city center
Brussels-Midi -> Brussels-Central
- Distance
- 1.6 km
- Travel time
- 8 min
- Contactless payment works on STIB-MIVB buses, trams, and metro via tap validators. A contactless fare is valid for 60 min.
- Brussels-Midi is served by SNCB/NMBS trains and STIB-MIVB metro, tram, and bus. Validate the correct ticket or payment method before boarding.
FAQs: Trains from Pisa to Brussels
Find answers to the most common questions about traveling from Pisa to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Train ticket prices from Pisa to Brussels can vary. The cheapest ticket starts at $277 (€228), while the average price is around $368 (€303).
The train from Pisa to Brussels takes 13h 9m and runs 2 per day.
The distance by train from Pisa to Brussels is 567 miles (914 km).
The first train from Pisa to Brussels leaves at 1:51 AM.
The last train from Pisa to Brussels leaves at 8:05 PM.
There is no high speed train available from Pisa to Brussels.
There is no direct train service currently available from Pisa to Brussels.
Unfortunately, there is no night train available from Pisa to Brussels.
The cheapest way to get from Pisa to Brussels is by flight, with a cost of around $23 (€19).
The train journey from Pisa to Brussels offers views of the picturesque Italian and Swiss countryside, including the rolling hills of Tuscany and the scenic landscapes of the Swiss Alps, making it a visually appealing route.
A day trip from Pisa to Brussels is not feasible as the travel duration is 13h 9m. The distance between the two cities is 567 miles (914 km), and the journey is available once per day by train.
In Brussels, explore the vibrant Marolles district with its antique shops and street art, and enjoy a stroll through Parc du Cinquantenaire with its impressive arches and museums. Sample Belgian chocolates at the city's renowned chocolatiers, and experience the lively Saint-Géry district's trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Don't miss top sights like the opulent Grand Place, Atomium for panoramic views, the iconic Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum.
For a fulfilling experience in Brussels, plan on spending 2 to 3 days to explore key attractions such as the Grand Place, Atomium, and various museums, as well as to enjoy the local cuisine and vibrant neighborhoods.
Yes, you can take the train from Pisa to Brussels.
Since both Pisa and Brussels are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Brussels include Bruges, Ghent, Antwerp, Lille, Rotterdam.
We recommend using the flight as it is the most popular way to get from Pisa to Brussels among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Belgium uses the euro (EUR) as its currency. Travelers generally find card payments widely accepted in cities, restaurants, and shops, though carrying some cash is advisable for small purchases or in rural areas.
In Brussels, travelers should be cautious of pickpocketing, especially in crowded areas like Grand Place, public transport, and popular tourist sites. Common scams include distraction techniques and fake petitions. It's advisable to stay vigilant, avoid displaying expensive items, and use official taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
Most popular train connections from Pisa
More options for your journey from Pisa to Brussels
Here are some other resources that might have the information you need
Most popular trains to and from Brussels and Pisa
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