- Recommended
Museo delle Sinopie
Pisa's main museum displays sculptures, paintings, manuscripts, and treasures from the cathedral complex and the city.

Cheapest price
$130
Average price
$130
Fastest journey
14h 50m
Average duration
14h 50m
Buses per day
1
Distance
62 km
Omio recommends booking the bus as it is the most popular option from Lyon to Pisa among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a train which can get you there in 9h 10m. The ticket price range depends on the travel mode: a bus costs an average of $58, and a flight costs an average of $246.
Distance: 306 miles (493 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$179 Average price | $98 Average price Cheapest | $726 Average price | $284 Average price (fuel + tolls) |
9h 40m Average total duration Fastest 9h 10m Onboard + 30m Additional time* | 10h 28m Average total duration 9h 58m Onboard + 30m Additional time* | 17h 55m Average total duration 14h 55m Onboard + 3h 0m Additional time* | 7h 14m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Pisa:
A bus is $81 (€67) less than a train for this route with tickets for a train from Lyon to Pisa costing on average $179 (€147).
A bus is $628 (€518) less than a flight for this route with tickets for a flight from Lyon to Pisa costing on average $726 (€598).
Other travel options to Pisa take longer:
Bus takes on average 9h 58m.
Flight takes on average 14h 55m.
Tickets start at around $179 (€147) compared to roughly $284 (€234) in fuel and tolls — a saving of about $106 (€87). The journey takes 9h 10m versus 7h 14m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Lyon to Pisa run on average 1 times per day, taking around 9h 10m. Cheap train tickets for this journey start at $147 (€121) but you can travel from only $58 (€48) by bus.
The earliest train runs at 00:09, the last at 20:20. The fastest train covers the 306 miles (493 km) distance in 8h 20m.
Distance 306 miles (493 km) |
Average train duration 9h 10m |
Cheapest ticket price $147 (€121) |
Trains per day 1 |
Fastest train 8h 20m |
First train 12:09 AM |
Last train 8:20 PM |
Cheapest Month Nov |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 14 days |
Discover the best of Pisa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Pisa trip today.
Pisa's main museum displays sculptures, paintings, manuscripts, and treasures from the cathedral complex and the city.
Museum of preparatory sinopias from Camposanto frescoes, offering rare insight into medieval artistic techniques and restoration.
Museum in Palazzo Lanfranchi with 19th- and 20th-century art, including works by Tuscan artists and temporary exhibitions.
Pisa's UNESCO square gathers the Leaning Tower, cathedral, baptistery, and cemetery in one extraordinary monumental ensemble.
Historic square framed by noble buildings and the Scuola Normale, central to Pisa's medieval civic and political life.
Lively riverside promenade ideal for walking, with historic palaces, bridges, and classic views of the Arno through the city center.
Cecina is a thin wood-fired chickpea flour pancake, crisp outside and soft inside. It is a classic street food across Pisa and coastal Tuscany.
Pappa al pomodoro is a thick bread and tomato soup with garlic, basil, and olive oil. It is a beloved Tuscan peasant dish often found in Pisa.
Ribollita is a hearty Tuscan soup of bread, beans, and vegetables, traditionally reheated the next day. It reflects the frugal home cooking of the area.
Well-known traditional trattoria serving classic Tuscan plates and local specialties in a warm, rustic atmosphere.
Casual, established spot famous for cecina and pizza in a lively local setting. Ideal for trying one of Pisa’s signature foods.
Historic Pisan restaurant known for refined Tuscan seafood and meat dishes in an elegant, traditional setting near the center.
Moderate for Italy. Budget eats and local transit are reasonable, but hotels near the Leaning Tower and peak-season dining cost more than in smaller Tuscan towns.
Service is often included or minimal. Round up or leave €1-2 at cafes, 5-10% for great restaurant service, and round up taxi fares.
Find answers to the most common questions about traveling from Lyon to Pisa by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Pisa, this guide helps you travel smarter and with confidence.

Most Lyon to Pisa trains use the Lyon Part Dieu to Pisa Centrale station pair. Use this guide to compare Lyon and Pisa train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
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