Catching the train to Pisa is a great way to visit one of the cradles of the Renaissance. Trains run into Pisa Centrale from Milan, Venice, Rome, Florence, Bologna, and almost all other major northern Italian cities, so there are connections for those touring Italy and passengers arriving from North America.
Most trains bound for Pisa will get into Pisa Centrale. The station isn't far from the historic center, including the Leaning Tower, and direct buses run to the famous attraction from just outside. Alternatively, travelers can hop onto suburban rail services and get off at San Rossore station, which is even closer to the city center. There's also a light rail service to the airport called PisaMover, which takes around five minutes.
The vast majority of trains to Pisa are operated by Trenitalia. Italy's national carrier offers basic fares which tend to be slightly slower, alongside Frecciarossa or Frecciargento fares, which provide faster connections and benefits like onboard WiFi.
Taking the train to Pisa has plenty of advantages. For one thing, the local airport only caters for regional and European connections, so travelers from North America or the rest of the world will need to transfer from Rome, Milan, or Venice. When doing so, Trenitalia services will be faster than buses, and more comfortable as well. They tend to be reliable, punctual, and rarely take longer than flights. Moreover, local rail links drop off passengers right next to Pisa's Duomo and the Leaning Tower, so there's no more convenient way to arrive.
When traveling to Pisa by train, remember that the nearest station to the historic center isn't Centrale, it's San Rossore, so factor in a short transfer upon arrival. When seeing the sights, many visitors like to buy passes for the hop-on hop-off tourist buses, but exploring on foot is a possibility as well. There's plenty to see besides the Tower and the cathedral. The Museo Nazionale hosts a superb sculpture collection, there are numerous smaller churches to discover, and don't forget the food. Pisa's take on Tuscan cooking mixes seafood and rustic dishes to create something unique. Mixed cheese platters, tagliolini pasta with clams, and peppered steaks are just a few delicacies that foodies will adore.