- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$160
Average price
$202
Fastest journey
5 h 56 m
Average duration
6 h 22 m
Trains per day
20
Distance
563 km
The best way to find a cheap train ticket from Frankfurt am Main to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Lyon will cost around $202 if you buy it on the day, but the cheapest tickets can be found for only $160.
Of the 20 trains that leave Frankfurt am Main for Lyon on Tue, Jun 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 02 the direct trains cover the 563 km distance in an average of 6 h 22 m but if you time it right, some trains will get you there in just 5 h 56 m .
On Tue, Jun 02 the slowest trains will take 6 h 58 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ICE 9568+
5537
ICE 9568+
12177
ICE 71+
TGV 9574+
12177
ECE 151+
TGV 9576+
12177
ICE 9590+
12177
9580
ICE 9568+
9877
9877+
9568
ICE 71+
TGV 9574+
9879
ICE 9590+
12177Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $30. For those with little time consider booking a flight which can get you there in 1h 57m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $30, and a flight costs an average of $171.
Distance: 349 miles (563 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$198 Average price | $55 Average price Cheapest | $400 Average price | $181 Average price (fuel + tolls) |
6h 36m Average total duration 6h 6m Onboard + 30m Additional time* | 10h 35m Average total duration 10h 5m Onboard + 30m Additional time* | 4h 57m Average total duration Fastest 1h 57m Onboard + 3h 0m Additional time* | 7h 16m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $142 (€115) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $198 (€159).
A bus is $344 (€277) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $400 (€322).
Other travel options to Lyon take longer:
Train takes on average 6h 6m.
Bus takes on average 10h 5m.
You'll arrive about 1h 10m sooner (6h 6m by train vs 7h 16m by car). Tickets start at around $198 (€159) compared to roughly $181 (€145) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Direct services run with TGV, SNCF | TGV INOUI.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Frankfurt am Main to Lyon trains for tomorrow, Tuesday, June 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9558+ 6611 | 5:54 AM Frankfurt (Main) Hbf | 7h02 | 12:56 PM Lyon Part Dieu | 1 transfer | |
ICE 9568+ 5537 | 6:53 AM Frankfurt (Main) Hbf | 11h06 | 5:59 PM Lyon Part Dieu | 1 transfer | |
ICE 9568+ 9877 | 6:53 AM Frankfurt (Main) Hbf | 6h07 | 1:00 PM Lyon Part Dieu | 1 transfer | |
ICE 9568+ 12177 | 6:53 AM Frankfurt (Main) Hbf | 11h06 | 5:59 PM Lyon Part Dieu | 1 transfer | |
9877+ 9568 | 6:53 AM Frankfurt (Main) Hbf | 6h07 | 1:00 PM Lyon Part Dieu | 1 transfer | |
ECE 151+ TGV 9576+ 12177 | 8:02 AM Frankfurt (Main) Hbf | 9h57 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ECE 151+ TGV 9576+ 9879 | 8:02 AM Frankfurt (Main) Hbf | 9h01 | 5:03 PM Lyon Part Dieu | 2 transfers | |
ECE 151+ TGV 9576+ 5537 | 8:02 AM Frankfurt (Main) Hbf | 9h57 | 5:59 PM Lyon Part Dieu | 2 transfers | |
9556+ 6617 | 8:53 AM Frankfurt (Main) Hbf | 7h03 | 3:56 PM Lyon Part Dieu | 1 transfer | |
ICE 71+ TGV 9574+ 12177 | 10:20 AM Frankfurt (Main) Hbf | 7h39 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ICE 71+ TGV 9574+ 9879 | 10:20 AM Frankfurt (Main) Hbf | 6h43 | 5:03 PM Lyon Part Dieu | 2 transfers | |
ICE 71+ TGV 9574+ 5537 | 10:20 AM Frankfurt (Main) Hbf | 7h39 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ICE 9590+ 12177 | 11:01 AM Frankfurt (Main) Hbf | 6h58 | 5:59 PM Lyon Part Dieu | 1 transfer | |
ICE 9590+ 5537 | 11:01 AM Frankfurt (Main) Hbf | 6h58 | 5:59 PM Lyon Part Dieu | 1 transfer | |
ICE 9590+ 96221+ 9222+ 12177 | 11:01 AM Frankfurt (Main) Hbf | 6h58 | 5:59 PM Lyon Part Dieu | 3 transfers | |
12177+ 9590 | 11:01 AM Frankfurt (Main) Hbf | 6h58 | 5:59 PM Lyon Part Dieu | 1 transfer | |
9552 · 6627 | 12:53 PM Frankfurt (Main) Hbf | 7h01 | 7:54 PM Lyon Part Dieu | 1 transfer | |
9580 | 2:02 PM Frankfurt (Main) Hbf | 5h56 | 7:58 PM Lyon Part Dieu | 0 transfersDirect | |
ICE 73 · ICE 9572+ 2362 · 6633 | 2:20 PM Frankfurt (Main) Hbf | 8h50 | 11:10 PM Lyon Part Dieu | 3 transfers | |
ICE 73 · ICE 9572+ 5488 · 9844 | 2:20 PM Frankfurt (Main) Hbf | 7h40 | 10:00 PM Lyon Part Dieu | 3 transfers | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Frankfurt am Main to Lyon run on average 4 times per day, taking around 6h 6m. Cheap train tickets for this journey start at $107 (€86) but you can travel from only $30 (€24) by bus.
There are 1 trains per day. The earliest train runs at 00:20, the last at 23:28. The fastest train covers the 349 miles (563 km) distance in 5h 51m.
Distance 349 miles (563 km) |
Average train duration 6h 6m |
Cheapest ticket price $107 (€86) |
Trains per day 4 |
Direct trains 1 |
Fastest train 5h 51m |
First train 12:20 AM |
Last train 11:28 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 35 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Part-Dieu -> Bellecour, Lyon
Find answers to the most common questions about traveling from Frankfurt am Main to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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