- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$172
Average price
$216
Fastest journey
5 h 56 m
Average duration
6 h 24 m
Trains per day
39
Distance
563 km
The best way to find a cheap train ticket from Frankfurt am Main to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Lyon will cost around $216 if you buy it on the day, but the cheapest tickets can be found for only $172.
Of the 39 trains that leave Frankfurt am Main for Lyon on Fri, Jul 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 17 the direct trains cover the 563 km distance in an average of 6 h 24 m but if you time it right, some trains will get you there in just 5 h 56 m .
On Fri, Jul 17 the slowest trains will take 6 h 58 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ICE 2557+
87430+
5537
ICE 2557+
87430+
12177
S3 · ICE 2557+
87424+
5537
S3 · ICE 2557+
87424+
12177
ICE 275+
87420+
9879
9580
9568+
12179
4503 · ICE 9568+
9877
4503 · ICE 9568+
12179
9590+
12177Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $29. For those with little time consider booking a flight which can get you there in 1h 57m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $29, and a flight costs an average of $168.
Distance: 349 miles (563 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$194 Average price | $54 Average price Cheapest | $392 Average price | $177 Average price (fuel + tolls) |
6h 36m Average total duration 6h 6m Onboard + 30m Additional time* | 10h 35m Average total duration 10h 5m Onboard + 30m Additional time* | 4h 57m Average total duration Fastest 1h 57m Onboard + 3h 0m Additional time* | 7h 16m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Lyon:
A bus is $140 (€115) less than a train for this route with tickets for a train from Frankfurt am Main to Lyon costing on average $194 (€159).
A bus is $338 (€277) less than a flight for this route with tickets for a flight from Frankfurt am Main to Lyon costing on average $392 (€322).
Other travel options to Lyon take longer:
Train takes on average 6h 6m.
Bus takes on average 10h 5m.
You'll arrive about 1h 10m sooner (6h 6m by train vs 7h 16m by car). Tickets start at around $194 (€159) compared to roughly $177 (€145) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Direct services run with TGV, SNCF | TGV INOUI.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Frankfurt am Main to Lyon trains for tomorrow, Friday, July 17. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9558+ 6611 | 5:54 AM Frankfurt (Main) Hbf | 7h02 | 12:56 PM Lyon Part Dieu | 1 transfer | |
4503 · ICE 9568+ 9877 | 6:30 AM Frankfurt South station | 6h29 | 12:59 PM Lyon Part Dieu | 2 transfers | |
4503 · ICE 9568+ 12179 | 6:30 AM Frankfurt South station | 6h29 | 12:59 PM Lyon Part Dieu | 2 transfers | |
4503 · ICE 9568+ 12189 | 6:30 AM Frankfurt South station | 10h33 | 5:03 PM Lyon Part Dieu | 2 transfers | |
ICE 275+ 87420+ 9879 | 6:50 AM Frankfurt (Main) Hbf | 10h13 | 5:03 PM Lyon Part Dieu | 2 transfers | |
ICE 275+ 87424+ 9879 | 6:50 AM Frankfurt (Main) Hbf | 10h13 | 5:03 PM Lyon Part Dieu | 2 transfers | |
ICE 275+ 87418+ 12189 | 6:50 AM Frankfurt (Main) Hbf | 10h13 | 5:03 PM Lyon Part Dieu | 2 transfers | |
9568+ 12179 | 6:53 AM Frankfurt (Main) Hbf | 6h06 | 12:59 PM Lyon Part Dieu | 1 transfer | |
ICE 591 · ICE 101 · 4719+ 87424 | 7:50 AM Frankfurt (Main) Hbf | 9h13 | 5:03 PM Lyon Part Dieu | 4 transfers | |
ICE 591 · ICE 101 · 4719+ 87424 | 7:50 AM Frankfurt (Main) Hbf | 9h13 | 5:03 PM Lyon Part Dieu | 4 transfers | |
S3 · ICE 2557+ 87424+ 12189 | 8:28 AM Frankfurt South station | 8h35 | 5:03 PM Lyon Part Dieu | 3 transfers | |
S3 · ICE 2557+ 87424+ 5537 | 8:28 AM Frankfurt South station | 9h31 | 5:59 PM Lyon Part Dieu | 3 transfers | |
S3 · ICE 2557+ 87424+ 12177 | 8:28 AM Frankfurt South station | 9h31 | 5:59 PM Lyon Part Dieu | 3 transfers | |
S3 · ICE 2557+ 87424+ 9879 | 8:28 AM Frankfurt South station | 8h35 | 5:03 PM Lyon Part Dieu | 3 transfers | |
ICE 2557+ 87430+ 5537 | 8:50 AM Frankfurt (Main) Hbf | 9h09 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ICE 2557+ 87430+ 12177 | 8:50 AM Frankfurt (Main) Hbf | 9h09 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ICE 2557+ 87440+ 12180 | 8:50 AM Frankfurt (Main) Hbf | 11h08 | 7:58 PM Lyon Part Dieu | 2 transfers | |
9556+ 6617 | 8:53 AM Frankfurt (Main) Hbf | 7h03 | 3:56 PM Lyon Part Dieu | 1 transfer | |
ICE 16 · ICE 103 · 4723+ 87430 | 9:18 AM Frankfurt (Main) Hbf | 8h41 | 5:59 PM Lyon Part Dieu | 4 transfers | |
ICE 16 · ICE 103 · 4723+ 87430 | 9:18 AM Frankfurt (Main) Hbf | 10h40 | 7:58 PM Lyon Part Dieu | 4 transfers | |
ICE 16 · ICE 103 · 4723+ 87430 | 9:18 AM Frankfurt (Main) Hbf | 8h41 | 5:59 PM Lyon Part Dieu | 4 transfers | |
15515 · ICE 71+ TGV 9574+ 12189 | 10:05 AM Frankfurt South station | 6h58 | 5:03 PM Lyon Part Dieu | 3 transfers | |
15515 · ICE 71+ TGV 9574+ 5537 | 10:05 AM Frankfurt South station | 7h54 | 5:59 PM Lyon Part Dieu | 3 transfers | |
15515 · ICE 71+ TGV 9574+ 12177 | 10:05 AM Frankfurt South station | 7h54 | 5:59 PM Lyon Part Dieu | 3 transfers | |
15515 · ICE 71+ TGV 9574+ 9879 | 10:05 AM Frankfurt South station | 6h58 | 5:03 PM Lyon Part Dieu | 3 transfers | |
ICE 71+ 87430+ 12177 | 10:20 AM Frankfurt (Main) Hbf | 7h39 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ICE 71+ 87430+ 5537 | 10:20 AM Frankfurt (Main) Hbf | 7h39 | 5:59 PM Lyon Part Dieu | 2 transfers | |
ICE 71+ 87438+ 9580 | 10:20 AM Frankfurt (Main) Hbf | 9h38 | 7:58 PM Lyon Part Dieu | 2 transfers | |
ICE 279+ 87440+ 12180 | 10:50 AM Frankfurt (Main) Hbf | 9h08 | 7:58 PM Lyon Part Dieu | 2 transfers | |
ICE 279+ 87438+ 9580 | 10:50 AM Frankfurt (Main) Hbf | 9h08 | 7:58 PM Lyon Part Dieu | 2 transfers | |
ICE 279+ 87432+ 9580 | 10:50 AM Frankfurt (Main) Hbf | 9h08 | 7:58 PM Lyon Part Dieu | 2 transfers | |
9590+ 12177 | 11:01 AM Frankfurt (Main) Hbf | 6h58 | 5:59 PM Lyon Part Dieu | 1 transfer | |
ICE 9590 · 17017+ 87438+ 9580 | 11:01 AM Frankfurt (Main) Hbf | 8h57 | 7:58 PM Lyon Part Dieu | 3 transfers | |
ICE 9590 · 17017+ 87440+ 12180 | 11:01 AM Frankfurt (Main) Hbf | 8h57 | 7:58 PM Lyon Part Dieu | 3 transfers | |
ICE 9590 · 17017+ 87440+ 9580 | 11:01 AM Frankfurt (Main) Hbf | 8h57 | 7:58 PM Lyon Part Dieu | 3 transfers | |
4519 · ICE 371+ 87438+ 9580 | 12:28 PM Frankfurt South station | 7h30 | 7:58 PM Lyon Part Dieu | 3 transfers | |
4519 · ICE 371+ 87438+ 12180 | 12:28 PM Frankfurt South station | 7h30 | 7:58 PM Lyon Part Dieu | 3 transfers | |
9552 · 6627 | 12:53 PM Frankfurt (Main) Hbf | 7h01 | 7:54 PM Lyon Part Dieu | 1 transfer | |
9580 | 2:02 PM Frankfurt (Main) Hbf | 5h56 | 7:58 PM Lyon Part Dieu | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Frankfurt am Main to Lyon run on average 4 times per day, taking around 6h 6m. Cheap train tickets for this journey start at $105 (€86) but you can travel from only $29 (€24) by bus.
There are 1 trains per day. The earliest train runs at 00:20, the last at 23:28. The fastest train covers the 349 miles (563 km) distance in 5h 51m.
Distance 349 miles (563 km) |
Average train duration 6h 6m |
Cheapest ticket price $105 (€86) |
Trains per day 4 |
Direct trains 1 |
Fastest train 5h 51m |
First train 12:20 AM |
Last train 11:28 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 35 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Frankfurt am Main to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need