4.9
4.6The cheapest and fastest trains from Pisa to Frankfurt am Main
Cheapest price
$281
Average price
$303
Fastest journey
11 h
Average duration
11 h
Trains per day
2
Distance
723 km
The best way to find a cheap train ticket from Pisa to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Frankfurt am Main will cost around $303 if you buy it on the day, but the cheapest tickets can be found for only $281.
It's difficult to get from Pisa to Frankfurt am Main without transferring at least 2 times.
Travel Information
Compare train, bus, and flight for Pisa to Frankfurt am Main
Omio recommends booking the flight as it is the most popular option from Pisa to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €56. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.8kg. The ticket price range depends on the travel mode: a bus costs an average of €56, and a flight costs an average of €134.
Distance: 449 miles (723 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€250 Average price | €376 Average price | €100 Average price Cheapest |
12h 3m Average total duration 11h 33m Onboard + 30m Additional time* | 5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 16h 47m Average total duration 16h 17m Onboard + 30m Additional time* |
- CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.7 - 1.8kg CO2 emissions Lowest |
 Most popular train company |  Most popular airline |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Frankfurt am Main train times
The table below shows live departures for Pisa to Frankfurt am Main trains for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:44 AM Pisa | 11h00 | 6:44 PM Frankfurt am Main | 3 transfers | |
| 7:44 AM Pisa | 11h00 | 6:44 PM Frankfurt am Main | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Frankfurt am Main by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Train from Pisa to Frankfurt am Main
Italy
Germany
Trains from Pisa to Frankfurt am Main run on average 1 times per day, taking around 11h 33m. Cheap train tickets for this journey start at $284 (€232) but you can travel from only $69 (€56) by bus.
The earliest train runs at 01:42, the last at 23:28. The fastest train covers the 449 miles (723 km) distance in 11h 0m.
Distance 449 miles (723 km) |
Average train duration 11h 33m |
Cheapest ticket price $284 (€232) |
Trains per day 1 |
Fastest train 11h 0m |
First train 01:42 |
Last train 23:28 |
Train companies: Trenitalia, Deutsche Bahn, Regionale from Pisa to Frankfurt am Main trainsTrenitalia, Deutsche Bahn, Regionale trains will get you between Pisa and Frankfurt am Main from $69 (€56). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Regionale
FAQs: Trains from Pisa to Frankfurt am Main
Find answers to the most common questions about traveling from Pisa to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.
popular train stations
Popular train stations from Pisa to Frankfurt am Main
WifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
- Merals Imbiss
- Bootshaus am Eisernen Steg
- Freigut
- Holbein's
- Hotel am Berg
- Leonardo Royal Hotel Frankfurt
- Hotel Ritter
- Lindner Main Plaza
Most popular train connections from Pisa
More options for your journey from Pisa to Frankfurt am Main
Here are some other resources that might have the information you need
Most popular trains to and from Frankfurt am Main and Pisa
Most popular train connections to Frankfurt am Main
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
