- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$202
Average price
$242
Fastest journey
7 h 7 m
Average duration
8 h 7 m
Trains per day
23
Distance
551 km
The best way to find a cheap train ticket from Florence to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence to Lyon will cost around $242 if you buy it on the day, but the cheapest tickets can be found for only $202.
It's difficult to get from Florence to Lyon without transferring at least once.
Regionale 17800 · Regionale Veloce TTPER 2460+
FRECCIAROSSA 1000 9296
Regionale 1792 · Regionale Veloce TTPER 2466+
FRECCIAROSSA 1000 9296
Regionale 1792 · Regionale TTPER 17412 · Regionale Veloce TTPER 2470+
FRECCIAROSSA 1000 9296
Intercity 580+
FRECCIAROSSA 1000 9296
Regionale 18510 · Regionale 17820+
Intercity 606+
FRECCIAROSSA 1000 9296
9928+
FRECCIAROSSA 1000 9296
FRECCIAROSSA 9514+
FRECCIAROSSA 1000 9296
9924+
FRECCIAROSSA 1000 9296
FRECCIAROSSA 9524+
FRECCIAROSSA 1000 9296
9920+
FRECCIAROSSA 1000 9296Omio recommends booking the bus as it is the most popular option from Florence to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $19. For those with little time consider booking a flight which can get you there in 3h 17m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.4kg. The ticket price range depends on the travel mode: a bus costs an average of $19, and a flight costs an average of $44.
Distance: 342 miles (551 km)
| Train | Most popular Bus | Flight |
|---|---|---|
$153 Average price | $46 Average price Cheapest | $232 Average price |
8h 53m Average total duration 8h 23m Onboard + 30m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 6h 17m Average total duration Fastest 3h 17m Onboard + 3h 0m Additional time* |
- CO2 emissions | 0.6 - 1.4kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Lyon:
A bus is $107 (€86) less than a train for this route with tickets for a train from Florence to Lyon costing on average $153 (€123).
A bus is $185 (€149) less than a flight for this route with tickets for a flight from Florence to Lyon costing on average $232 (€187).
Other travel options to Lyon take longer:
Train takes on average 8h 23m.
Bus takes on average 13h 39m.
The table below shows live departures for Florence to Lyon trains for tomorrow, Sunday, May 31. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 17800 · Regionale Veloce TTPER 2460+ FRECCIAROSSA 1000 9296 | 4:32 AM Florence Santa Maria Novella | 16h00 | 8:32 PM Lyon Part Dieu | 2 transfers | |
FRECCIAROSSA 9504+ FRECCIAROSSA 1000 9296 | 6:55 AM Florence Santa Maria Novella | 13h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 1792 · Regionale Veloce TTPER 2466+ FRECCIAROSSA 1000 9296 | 7:17 AM Florence Santa Maria Novella | 13h15 | 8:32 PM Lyon Part Dieu | 2 transfers | |
FRECCIAROSSA 9400 · FRECCIAROSSA 9802+ FRECCIAROSSA 1000 9296 | 7:20 AM Florence Santa Maria Novella | 13h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Regionale 1792 · Regionale TTPER 17412 · Regionale Veloce TTPER 2470+ FRECCIAROSSA 1000 9296 | 7:25 AM Florence Rifredi | 13h07 | 8:32 PM Lyon Part Dieu | 3 transfers | |
FRECCIAROSSA 9508+ FRECCIAROSSA 1000 9296 | 7:55 AM Florence Santa Maria Novella | 12h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9404 · FRECCIAROSSA 9610+ FRECCIAROSSA 1000 9296 | 8:20 AM Florence Santa Maria Novella | 12h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
Intercity 580+ FRECCIAROSSA 1000 9296 | 8:21 AM Florence Santa Maria Novella | 12h11 | 8:32 PM Lyon Part Dieu | 1 transfer | |
9908+ FRECCIAROSSA 1000 9296 | 8:25 AM Florence Santa Maria Novella | 12h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 94467+ Intercity 606+ FRECCIAROSSA 1000 9296 | 8:40 AM Florence Santa Maria Novella | 11h52 | 8:32 PM Lyon Part Dieu | 2 transfers | |
FRECCIAROSSA 9512+ FRECCIAROSSA 1000 9296 | 8:55 AM Florence Santa Maria Novella | 11h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
9912+ FRECCIAROSSA 1000 9296 | On time 9:25 AM Florence Santa Maria Novella | 11h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9516+ FRECCIAROSSA 1000 9296 | 9:55 AM Florence Santa Maria Novella | 10h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale 18510 · Regionale 17820+ Intercity 606+ FRECCIAROSSA 1000 9296 | 10:09 AM Florence Santa Maria Novella | 10h23 | 8:32 PM Lyon Part Dieu | 3 transfers | |
FRECCIAROSSA 9490 · FRECCIAROSSA 8810+ FRECCIAROSSA 1000 9296 | 10:20 AM Florence Santa Maria Novella | 10h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
9916+ FRECCIAROSSA 1000 9296 | On time 10:25 AM Florence Santa Maria Novella | 10h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9520+ FRECCIAROSSA 1000 9296 | 10:55 AM Florence Santa Maria Novella | 9h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9414 · FRECCIAROSSA 9806+ FRECCIAROSSA 1000 9296 | 11:20 AM Florence Santa Maria Novella | 9h12 | 8:32 PM Lyon Part Dieu | 2 transfers | |
9920+ FRECCIAROSSA 1000 9296 | On time 11:25 AM Florence Santa Maria Novella | 9h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9524+ FRECCIAROSSA 1000 9296 | 11:55 AM Florence Santa Maria Novella | 8h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
9924+ FRECCIAROSSA 1000 9296 | 12:25 PM Florence Santa Maria Novella | 8h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
FRECCIAROSSA 9514+ FRECCIAROSSA 1000 9296 | 12:55 PM Florence Santa Maria Novella | 7h37 | 8:32 PM Lyon Part Dieu | 1 transfer | |
9928+ FRECCIAROSSA 1000 9296 | On time 1:25 PM Florence Santa Maria Novella | 7h07 | 8:32 PM Lyon Part Dieu | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Florence to Lyon run on average 1 times per day, taking around 8h 23m. Cheap train tickets for this journey start at $104 (€84) but you can travel from only $19 (€15) by bus.
The earliest train runs at 00:40, the last at 21:57. The fastest train covers the 342 miles (551 km) distance in 7h 12m.
Distance 342 miles (551 km) |
Average train duration 8h 23m |
Cheapest ticket price $104 (€84) |
Trains per day 1 |
Fastest train 7h 12m |
First train 12:40 AM |
Last train 9:57 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 77 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Part-Dieu -> Bellecour, Lyon
Find answers to the most common questions about traveling from Florence to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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