- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$288
Average price
$309
Fastest journey
13 h 27 m
Average duration
13 h 55 m
Trains per day
2
Distance
860 km
The best way to find a cheap train ticket from Prague to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Lyon will cost around $309 if you buy it on the day, but the cheapest tickets can be found for only $288.
Of the 2 trains that leave Prague for Lyon on Wed, Jul 15, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 15 the direct trains cover the 860 km distance in an average of 13 h 55 m but if you time it right, some trains will get you there in just 13 h 27 m .
On Wed, Jul 15 the slowest trains will take 14 h 23 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the flight as it is the most popular option from Prague to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a flight which can get you there in 2h 43m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $58, and a train costs an average of $282.
Distance: 534 miles (860 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$306 Average price | $203 Average price | $85 Average price Cheapest | $262 Average price (fuel + tolls) |
14h 30m Average total duration 14h 0m Onboard + 30m Additional time* | 5h 43m Average total duration Fastest 2h 43m Onboard + 3h 0m Additional time* | 17h 2m Average total duration 16h 32m Onboard + 30m Additional time* | 9h 53m Average total duration (door-to-door) |
- CO2 emissions | 2.6 - 5.2kg CO2 emissions | 0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Lyon:
A bus is $117 (€97) less than a flight for this route with tickets for a flight from Prague to Lyon costing on average $203 (€167).
A bus is $221 (€182) less than a train for this route with tickets for a train from Prague to Lyon costing on average $306 (€252).
Other travel options to Lyon take longer:
Train takes on average 14h 0m.
Bus takes on average 16h 32m.
Tickets start at around $306 (€252) compared to roughly $262 (€216) in fuel and tolls — a saving of about $-43.76 (€-36.10). The journey takes 14h 0m versus 9h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Prague to Lyon run on average 1 times per day, taking around 14h 0m. Cheap train tickets for this journey start at $282 (€232) but you can travel from only $58 (€48) by bus.
The earliest train runs at 05:20, the last at 17:00. The fastest train covers the 534 miles (860 km) distance in 13h 27m.
Distance 534 miles (860 km) |
Average train duration 14h 0m |
Cheapest ticket price $282 (€232) |
Trains per day 1 |
Fastest train 13h 27m |
First train 5:20 AM |
Last train 5:00 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 56 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Prague to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Prague to Lyon trains use the Praha hlavní nádraží to Lyon Part Dieu station pair. Use this guide to compare Prague and Lyon train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
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