- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
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The cheapest and fastest buses from Pisa to Lyon
Showing times and prices for Jun 06
Cheapest price
$58
Average price
$89
Fastest journey
12 h 30 m
Average duration
13 h 54 m
Buses per day
8
Distance
493 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Lyon will cost around $89 if you buy it on the day, but the cheapest tickets can be found for only $58.
Fast buses
Of the 8 buses that leave Pisa for Lyon on Sat, Jun 06, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 06 the direct buses cover the 493 km distance in an average of 13 h 54 m but if you time it right, some buses will get you there in just 12 h 30 m .
On Sat, Jun 06 the slowest buses will take 14 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:10 AM15h30Pisa9:40 PMLyon$581One-way0 transfers- 5:10 PM14h35Pisa7:45 AMLyon$701One-way0 transfers
- 6:15 AM15h25Pisa9:40 PMLyon$701One-way0 transfers
- 3:45 PM12h30Pisa4:15 AMLyon$831One-way0 transfers
- 5:15 PM14h30Pisa7:45 AMLyon$941One-way0 transfers
- 3:45 PM12h30Pisa4:15 AMLyon$831One-way0 transfers
- 3:10 PM13h20Pisa4:30 AMLyon$1261One-way0 transfers
- 5:15 PM14h30Pisa7:45 AMLyon$941One-way0 transfers
- 5:10 PM14h35Pisa7:45 AMLyon$701One-way0 transfers
- 4:10 PM14h35Pisa6:45 AMLyon$1131One-way0 transfers
Travel Information
Compare train, bus, and flight for Pisa to Lyon
Omio recommends booking the bus as it is the most popular option from Pisa to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $54. For those with little time consider booking a train which can get you there in 7h 51m. The ticket price range depends on the travel mode: a bus costs an average of $54, and a flight costs an average of $107.
Distance: 306 miles (493 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$89 Average price Cheapest | $131 Average price | $513 Average price | $291 Average price (fuel + tolls) |
11h 26m Average total duration 10h 56m Onboard + 30m Additional time* | 8h 21m Average total duration Fastest 7h 51m Onboard + 30m Additional time* | 18h 27m Average total duration 15h 27m Onboard + 3h 0m Additional time* | 7h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Pisa to Lyon is a bus with an average price of $89 (€72).
This is compared to other travel options from Pisa to Lyon:
A bus is $42 (€34) less than a train for this route with tickets for a train from Pisa to Lyon costing on average $131 (€106).
A bus is $424 (€343) less than a flight for this route with tickets for a flight from Pisa to Lyon costing on average $513 (€415).
The fastest way to travel from Pisa to Lyon is by train with an average journey time of 7h 51m.
Other travel options to Lyon take longer:
Bus takes on average 10h 56m.
Flight takes on average 15h 27m.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Lyon including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from Pisa to Lyon among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $89 (€72) compared to roughly $291 (€235) in fuel and tolls — a saving of about $202 (€163). The journey takes 10h 56m versus 7h 32m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Pisa to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:25AM | Arrival Time 04:10PM | Duration 11h45 | Departure days Fri | Cheapest price $80 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 08:40PM | Duration 15h25 | Departure days Fri, Sat | Cheapest price $96 |
Operator FlixBus | Departure Time 05:25AM | Arrival Time 05:10PM | Duration 11h45 | Departure days Fri | Cheapest price $57 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 06:10PM | Duration 12h25 | Departure days Tue | Cheapest price $79 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 09:40PM | Duration 15h30 | Departure days Sat | Cheapest price $58 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 09:40PM | Duration 15h25 | Departure days Fri, Sat | Cheapest price $70 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 06:10PM | Duration 11h45 | Departure days Mon, Thu, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 11:45PM | Duration 16h30 | Departure days Tue, Wed | Cheapest price $69 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 09:45PM | Duration 14h05 | Departure days Fri | Cheapest price $82 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 03:30PM | Duration 6h30 | Departure days Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 10:40PM | Duration 13h00 | Departure days Mon, Thu, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 02:50AM | Duration 14h00 | Departure days Fri | Cheapest price $74 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 03:55AM | Duration 14h05 | Departure days Mon, Thu, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 04:30AM | Duration 13h20 | Departure days Sat | Cheapest price $126 |
Operator FlixBus | Departure Time 03:45PM | Arrival Time 04:15AM | Duration 12h30 | Departure days Sat | Cheapest price $83 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 06:45AM | Duration 14h35 | Departure days Fri, Sat | Cheapest price $113 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 07:45AM | Duration 14h35 | Departure days Everyday | Cheapest price $70 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 07:45AM | Duration 14h30 | Departure days Fri, Sat | Cheapest price $94 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 08:45AM | Duration 14h35 | Departure days Wed, Thu, Sun | Cheapest price $70 |
Live departures
Pisa to Lyon bus times
The table below shows live departures for Pisa to Lyon buses for today, Friday, June 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:40 AM Pisa | 14h05 | 9:45 PM Lyon | 0 transfersDirect | |
| 12:50 PM Pisa | 14h00 | 2:50 AM Lyon | 0 transfersDirect | |
| 4:10 PM Pisa | 14h35 | 6:45 AM Lyon | 0 transfersDirect | |
| 5:10 PM Pisa | 14h35 | 7:45 AM Lyon | 0 transfersDirect | |
| 5:15 PM Pisa | 14h30 | 7:45 AM Lyon | 0 transfersDirect | |
| 5:15 AM Pisa | 15h25 | 8:40 PM Lyon | 0 transfersDirect | |
| 6:10 AM Pisa | 15h30 | 9:40 PM Lyon | 0 transfersDirect | |
| 6:15 AM Pisa | 15h25 | 9:40 PM Lyon | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa to Lyon buses with Omio?
FlixBus as well as Consorzio Pisano Trasporti offer buses services from Pisa to Lyon.
Omio is an official ticket reseller for all your travel options from Pisa to Lyon.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Consorzio Pisano Trasporti to find the best option for your trip from Pisa to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Lyon.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Lyon.
Journey information
Overview: Bus from Pisa to Lyon
Italy
France
Buses from Pisa to Lyon run on average 5 times per day, taking around 10h 56m. Cheap bus tickets for this journey start at $54 (€44) if you book in advance.
The earliest bus runs at 00:05, the last at 23:00. The fastest bus covers the 306 miles (493 km) distance in 11h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 306 miles (493 km) |
Average bus duration 10h 56m |
Cheapest ticket price $54 (€44) |
Buses per day 5 |
Fastest bus 11h 45m |
First bus 12:05 AM |
Last bus 11:00 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, BlaBlaCar, Consorzio Pisano Trasporti from Pisa to LyonYou can travel by bus between Pisa to Lyon with FlixBus, BlaBlaCar, Consorzio Pisano Trasporti for as low as $54 (€44). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 45m
Cheapest Price
$54 (€44)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
1 a day
Consorzio Pisano Trasporti
Luggage & cancellation policy
Average Duration
11h 50m
Cheapest Price
$64 (€52)
Consorzio Pisano Trasporti frequency
1 a day
Complete guide to Lyon
Things to do in Lyon
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
- Must visit
Musée des Beaux-Arts de Lyon
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
- Recommended
Lugdunum - Musée et Théâtres romains
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
- Must visit
Vieux Lyon
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
- Must visit
Place Bellecour
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
- Must visit
Parc de la Tête d'Or
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Quenelles De Brochet
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
Salade Lyonnaise
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Saucisson Brioché
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
La Mère Brazier
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
Les Halles De Lyon Paul Bocuse
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
Daniel Et Denise
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Euro
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Average meal costs
- Budget
- EUR 10-15 for a bakery lunch or kebab.
- Mid-range
- EUR 20-35 per person at a casual restaurant.
- Fine dining
- EUR 70+ per person at upscale restaurants.
- Coffee
- EUR 2.50-4 for an espresso or cappuccino.
Tipping culture
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
TCL: Itinéraires & Tickets
Get the appOfficial public transport app
Prices
- Single ticket
- 2.00 EUR
- Day pass
- 6.70 EUR
To the city center
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
- Distance
- 4 km
- Travel time
- 15 min
- You can buy tickets in the official TCL app, at ticket machines, or at metro and tram stops. Contactless bank card payment is available on TCL buses and trams.
- Validate your ticket when boarding or entering the network, and keep it until the end of your journey. A Day Pass is usually best value if you plan several trips in one day.
FAQs: Bus from Pisa to Lyon
Find answers to the most common questions about traveling from Pisa to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Lyon can start from as little as $54 (€44) when you book in advance. The average bus ticket price for Pisa to Lyon is $89 (€72) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Lyon is 11h 45m to travel the 306 miles (493 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Lyon leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Lyon leaves at 11:00 PM.
There are 5 buses a day from Pisa to Lyon which require at least one change with FlixBus, BlaBlaCar, Consorzio Pisano Trasporti. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Lyon, you can count on FlixBus, BlaBlaCar, Consorzio Pisano Trasporti for the best way to get you to Lyon. You can also check all possible bus companies who offer a service between Pisa and Lyon and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Aeroporto Parcheggio Aurelia, Lucca, Viale Regina Margherita / Via Montanara . When arriving in Lyon , you can end your journey in bus stations like Lyon, Perrache Bus Station, Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Colombier-Saugnieu, Lyon - Saint-Exupéry Airport (Arrivée T1) .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 away from the city centre, and they get off the bus at Lyon, Perrache Bus Station, located 1 away from the city centre.
A trip to Lyon from Pisa is worth doing but not as a day trip with a journey time of 11h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Lyon is July.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Lyon including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pisa to Lyon:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pisa to Lyon for bus company FlixBus.
Some of the most interesting sights to explore in Lyon are:
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
The best things to do in Lyon include:
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
Whether you can cancel your bus ticket from Pisa to Lyon depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Lyon.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Lyon:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Lyon:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Lyon. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Lyon with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Lyon with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Lyon with the following bus company: FlixBus.
Since both Pisa and Lyon are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Pisa to Lyon among Omio's users.
France uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most transactions, especially in cities and larger establishments, but carrying some cash is advisable for small vendors, markets, and rural areas where card acceptance may be limited.
In Lyon, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, popular tourist spots, and markets. Common scams include distraction techniques and fake charity collectors. It's advisable to keep valuables secure and be wary of overly friendly strangers offering unsolicited help. Avoid unlicensed taxi services to prevent overcharging. Staying alert in busy zones ensures a safer visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Lyon
Pisa
Lyon
The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Lyon.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
information
Pisa, Aeroporto Parcheggio Aurelia
information
The major bus station for arrivals in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip to Lyon from Pisa.
Lyon, Gare Routière de Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
Cours de VerdunWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Lyon, Gare Routière de Perrache
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
information
Most popular bus connections from Pisa
More options for your journey from Pisa to Lyon
Here are some other resources that might have the information you need
Most popular buses to and from Lyon and Pisa
Most popular bus connections to Lyon
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