- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
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The cheapest and fastest buses from Pisa to Lyon
Showing times, prices and bookable tickets for Oct 20
Cheapest price on Oct 20
$61
Average ticket price on Oct 20
$64
Fastest journey on Oct 20
12 h 25 m
Average journey duration on Oct 20
14 h 28 m
Buses on Oct 20
2
Distance
493 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Lyon will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $61.
Fast buses
It's difficult to get from Pisa to Lyon without transferring at least once.
FlixBus · FlixBus5:45 AM12h25Pisa (Pisamover via San Giusto/Aurelia)6:10 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$611One-way1 transfer- FlixBus · FlixBus7:15 AM16h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$671One-way1 transfer
- FlixBus · FlixBus5:45 AM12h25Pisa (Pisamover via San Giusto/Aurelia)6:10 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$611One-way1 transfer
- FlixBus · FlixBus7:15 AM16h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$671One-way1 transfer
Journey information
Overview: Bus from Pisa to Lyon
Italy
France
Buses from Pisa to Lyon run on average 4 times per day, taking around 11h 25m. Cheap bus tickets for this journey start at $44 but you can travel from only $3 by train.
The earliest bus runs at 00:05, the last at 23:00. The fastest bus covers the 306 miles (493 km) distance in 9h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $3
Distance 306 miles (493 km) |
Average bus duration 11h 25m |
Cheapest ticket price $44 |
Buses per day 4 |
Fastest bus 9h 15m |
First bus 12:05 AM |
Last bus 11:00 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Fri |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $3
Pisa to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:45AM | Arrival Time 06:10PM | Duration 13h25 | Departure days Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 05:25AM | Arrival Time 06:10PM | Duration 12h45 | Departure days Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 06:10PM | Duration 12h25 | Departure days Tue | Cheapest price $61 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 06:10PM | Duration 11h45 | Departure days Mon, Thu, Fri, Sat | Cheapest price $99 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 11:45PM | Duration 16h30 | Departure days Tue, Wed, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 10:40PM | Duration 13h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $93 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 03:55AM | Duration 15h55 | Departure days Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 01:50PM | Arrival Time 03:55AM | Duration 14h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 06:30AM | Duration 13h45 | Departure days Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 06:30AM | Duration 13h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 08:45AM | Duration 14h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $91 |
Live departures
Pisa to Lyon bus times
The table below shows live departures for Pisa to Lyon buses for today, Monday, October 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h20 | 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Tuesday, October 20 | |||||
| FlixBus · FlixBus | 5:45 AM Pisa (Pisamover via San Giusto/Aurelia) | 12h25 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h30 | 11:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Pisa to Lyon buses with Omio?
FlixBus operates all buses services from Pisa to Lyon.
Omio is an official ticket reseller for all your travel options from Pisa to Lyon.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Lyon.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Lyon.
Bus providers: FlixBus from Pisa to LyonYou can travel by bus between Pisa to Lyon with FlixBus for as low as $3. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 15m
Cheapest FlixBus Price
$44
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Lyon
Things to do in Lyon
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
- Must visit
Musée Cinéma et Miniature
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
- Must visit
Musée des Confluences
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
- Must visit
Vieux Lyon
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
- Must visit
Presqu'île
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
- Must visit
La Croix-Rousse
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Quenelles De Brochet
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Salade Lyonnaise
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
- Vegetarian
- Gluten-free
Cervelle De Canut
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
L'Auberge Du Pont De Collonges
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Le Musée
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Café Comptoir Abel
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Euro (€)
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Average meal costs
- Budget
- €8-15 for fast food or a simple lunch.
- Mid-range
- €20-35 per person for a meal.
- Fine dining
- €70+ per person for upscale restaurants.
- Coffee
- €2.50-4 for coffee or cappuccino.
Tipping culture
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
FAQs: Bus from Pisa to Lyon
Find answers to the most common questions about traveling from Pisa to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Lyon can start from as little as $44 when you book in advance. The average bus ticket price for Pisa to Lyon is $102 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Lyon is 9h 15m to travel the 306 miles (493 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Lyon leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Lyon leaves at 11:00 PM.
There are 4 buses a day from Pisa to Lyon which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Pisa to Lyon, you can count on FlixBus for the best way to get you to Lyon. You can also check all possible bus companies who offer a service between Pisa and Lyon and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa (Pisamover via San Giusto/Aurelia) . When arriving in Lyon , you can end your journey in bus stations like Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Lyon, Perrache Bus Station .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), located 2 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Lyon including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Pisa to Lyon for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Pisa to Lyon:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Pisa to Lyon depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Lyon.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Lyon:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Lyon:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Lyon. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Lyon with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Pisa to Lyon with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Pisa to Lyon with the following bus company: FlixBus.
France uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most transactions, especially in cities and larger establishments, but carrying some cash is advisable for small vendors, markets, and rural areas where card acceptance may be limited.
In Lyon, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, popular tourist spots, and markets. Common scams include distraction techniques and fake charity collectors. It's advisable to keep valuables secure and be wary of overly friendly strangers offering unsolicited help. Avoid unlicensed taxi services to prevent overcharging. Staying alert in busy zones ensures a safer visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Lyon
Most Pisa to Lyon buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Pisa and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Pisa
Arrival bus stations in Lyon
Which Pisa station do buses to Lyon leave from?
Buses from Pisa to Lyon leave from Pisa, Via delle Fiamme Gialle (Park Pietrasantina). The station is 1 miles (2 km) from Pisa city centre at Pisa Pietrasantina Parking, 56123 Pisa PI, Italy.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)Pisa Pietrasantina Parking, 56123 Pisa PI, Italy
City-centre transport
Getting to Pisa, Via delle Fiamme Gialle (Park Pietrasantina) from Pisa city centre
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Bus21, E24, 1+ · 12m · $2 · every ~10 min
1+, 21 · 14m · $2 · every ~9 min
1+ · 24m · $3 · every ~9 min
21 · 30m · $3
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) bus station facilities and services
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi and ATMs
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Tickets and information
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Parking, taxis and toilets
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Bike and car services
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia)Via S. Giusto, 56121 Pisa PI, Italy
City-centre transport
Getting to Pisa (Pisamover via San Giusto/Aurelia) from Pisa city centre
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Bus15 · 5m · $2 · every ~3 min
15 · 7m · $2 · every ~3 min
15 · 9m · $2 · every ~3 min
Pisa (Pisamover via San Giusto/Aurelia) bus station facilities and services
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Tickets and information
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Parking, taxis and toilets
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Which Lyon station do buses from Pisa arrive at?
Buses from Pisa to Lyon most often arrive at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). Some services arrive at Lyon, Gare Routière de Perrache, so check your ticket before travel to confirm your Lyon arrival station.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)52 Av. Tony Garnier, 69007 Lyon, France
City-centre transport
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
BusN734 · 15m · $2
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache13 Cours de Verdun, 69002 Lyon, France
City-centre transport
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
TrainTer · 5m · $2 · every ~5 min
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
More options for your journey from Pisa to Lyon
Here are some other resources that might have the information you need
Most popular buses to and from Lyon and Pisa
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