Travel Information
Compare bus and train for Indianapolis, IN to San Antonio, TX
Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from €103. For those with little time consider booking a bus which can get you there in 30h 13m. The ticket price range depends on the travel mode: a bus costs an average of €103, and a train costs an average of €245.
Distance: 999 miles (1609 km)
Compare bus with
Most popular Bus | Train |
|---|---|
€134 Average price Cheapest | €245 Average price |
30h 43m Average total duration Fastest 30h 13m Onboard + 30m Additional time* | 35h 13m Average total duration 34h 43m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Indianapolis, IN to San Antonio, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:15AM | Arrival Time 12:55PM | Duration 34h40 | Departure days Sun | Cheapest price $246 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 11:25PM | Duration 45h10 | Departure days Sun | Cheapest price $244 |
Operator Greyhound | Departure Time 11:25AM | Arrival Time 11:25PM | Duration 37h00 | Departure days Wed, Sun | Cheapest price $200 |
Operator Greyhound | Departure Time 03:05PM | Arrival Time 11:55PM | Duration 33h50 | Departure days Sun | Cheapest price $239 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 05:35PM | Duration 26h45 | Departure days Wed, Sun | Cheapest price $197 |
Operator Greyhound | Departure Time 06:25PM | Arrival Time 11:55PM | Duration 30h30 | Departure days Wed, Sun | Cheapest price $200 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 11:55PM | Duration 28h45 | Departure days Wed, Sun | Cheapest price $199 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 11:25PM | Duration 48h55 | Departure days Sun | Cheapest price $237 |
Compare prices and tickets Indianapolis, IN to San Antonio, TX by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Indianapolis, IN to San Antonio, TX
Buses from Indianapolis, IN to San Antonio, TX run on average 8 times per day, taking around 30h 13m. Cheap bus tickets for this journey start at $128 (€103) if you book in advance.
The earliest bus runs at 01:30, the last at 23:55. The fastest bus covers the 999 miles (1609 km) distance in 26h 45m.
Distance 999 miles (1609 km) |
Average bus duration 30h 13m |
Cheapest ticket price $128 (€103) |
Buses per day 8 |
Fastest bus 26h 45m |
First bus 01:30 |
Last bus 23:55 |
Bus providers: Greyhound from Indianapolis, IN to San Antonio, TXYou can travel by bus between Indianapolis, IN to San Antonio, TX with Greyhound for as low as $128 (€103). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Indianapolis, IN to San Antonio, TX
Find answers to the most common questions about traveling from Indianapolis, IN to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- Take a boat tour along the San Antonio River for a unique perspective of the city
- Visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- Enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- Experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Indianapolis, IN to San Antonio, TX, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
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Popular bus stations from Indianapolis, IN to San Antonio, TX
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