- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
Cheapest price
$130
Average price
$134
Fastest journey
1 d 10 h 40 m
Average duration
1 d 11 h 55 m
Buses per day
2
Distance
1609 km
The best way to find a cheap bus ticket from Indianapolis, IN to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to San Antonio, TX will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $130.
Of the 2 buses that leave Indianapolis, IN for San Antonio, TX on Sun, Aug 16, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Aug 16 the direct buses cover the 1609 km distance in an average of 1 d 11 h 55 m but if you time it right, some buses will get you there in just 1 d 10 h 40 m .
On Sun, Aug 16 the slowest buses will take 1 d 13 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $130. For those with little time consider booking a flight which can get you there in 4h 24m. The ticket price range depends on the travel mode: a bus costs an average of $130, and a flight costs an average of $176.
Distance: 999 miles (1609 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$203 Average price Cheapest | $274 Average price | $326 Average price | $233 Average price (fuel + tolls) |
30h 43m Average total duration 30h 13m Onboard + 30m Additional time* | 35h 13m Average total duration 34h 43m Onboard + 30m Additional time* | 7h 24m Average total duration Fastest 4h 24m Onboard + 3h 0m Additional time* | 17h 35m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Indianapolis, IN to San Antonio, TX:
A bus is $71 (€58) less than a train for this route with tickets for a train from Indianapolis, IN to San Antonio, TX costing on average $274 (€222).
A bus is $123 (€100) less than a flight for this route with tickets for a flight from Indianapolis, IN to San Antonio, TX costing on average $326 (€265).
Other travel options to San Antonio, TX take longer:
Bus takes on average 30h 13m.
Train takes on average 34h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:10AM | Arrival Time 04:55AM | Duration 28h45 | Departure days Thu | Cheapest price $238 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 10:00AM | Duration 30h30 | Departure days Sat | Cheapest price $194 |
Operator Greyhound | Departure Time 04:30AM | Arrival Time 05:25AM | Duration 48h55 | Departure days Sun | Cheapest price $211 |
Operator Amtrak Thruway | Departure Time 05:15AM | Arrival Time 01:18PM | Duration 32h03 | Departure days Thu | Cheapest price $381 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 06:55PM | Duration 34h40 | Departure days Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 04:25AM | Duration 37h10 | Departure days Sun | Cheapest price $139 |
Operator Greyhound | Departure Time 04:25PM | Arrival Time 06:55PM | Duration 26h30 | Departure days Wed | Cheapest price $304 |
The table below shows live departures for Indianapolis, IN to San Antonio, TX buses for tomorrow, Sunday, August 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 AM Indianapolis, IN | 34h40 | 6:55 PM San Antonio, TX | 0 transfersDirect | |
![]() | 3:15 PM Indianapolis, IN | 37h10 | 4:25 AM San Antonio, TX | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Indianapolis, IN to San Antonio, TX run on average 9 times per day, taking around 30h 13m. Cheap bus tickets for this journey start at $130 (€106) if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 999 miles (1609 km) distance in 26h 30m.
Distance 999 miles (1609 km) |
Average bus duration 30h 13m |
Cheapest ticket price $130 (€106) |
Buses per day 9 |
Fastest bus 26h 30m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 3 days |
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Find answers to the most common questions about traveling from Indianapolis, IN to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Indianapolis, IN to San Antonio, TX buses use the Indianapolis, Illinois St (Greyhound Bus Station) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare Indianapolis, IN and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food outlets are available.
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Indianapolis, E Washington St / N Delaware St (City/County Building) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Indianapolis, E Washington St / N Delaware St (City/County Building). ATMs are available at Indianapolis, E Washington St / N Delaware St (City/County Building).
Ticket office support is available at Indianapolis, E Washington St / N Delaware St (City/County Building).
Available at Indianapolis, E Washington St / N Delaware St (City/County Building): Parking, Taxis, WC.
Accessibility facilities are available at Indianapolis, E Washington St / N Delaware St (City/County Building): Wheelchair accessible buses available.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Here are some other resources that might have the information you need