- Must visit
San Antonio Museum of Art
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
The best way to find a cheap bus ticket from Indianapolis, IN to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to San Antonio, TX will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $110.
It's difficult to get from Indianapolis, IN to San Antonio, TX without transferring at least 2 times.
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Buses from Indianapolis, IN to San Antonio, TX run on average 9 times per day, taking around 27h 56m. Cheap bus tickets for this journey start at $99 if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 999 miles (1609 km) distance in 22h 55m.
Distance 999 miles (1609 km) |
Average bus duration 27h 56m |
Cheapest ticket price $99 |
Buses per day 9 |
Fastest bus 22h 55m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Best time to book 3 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Indianapolis, IN to San Antonio, TX.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:15AM | Arrival Time 12:55PM | Duration 34h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 08:25PM | Duration 42h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 04:40AM | Arrival Time 05:10AM | Duration 25h30 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 08:25PM | Duration 34h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 12:20AM | Duration 38h05 | Departure days Fri, Sat, Sun | Cheapest price $110 |
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:55PM | Duration 26h40 | Departure days Everyday | Cheapest price $110 |
Operator Greyhound | Departure Time 04:05PM | Arrival Time 06:10PM | Duration 27h05 | Departure days Everyday | Cheapest price $110 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 12:05AM | Duration 30h30 | Departure days Everyday | Cheapest price $110 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 08:25PM | Duration 49h15 | Departure days Everyday | Cheapest price $110 |
Operator Greyhound | Departure Time 11:20PM | Arrival Time 11:20PM | Duration 49h00 | Departure days Sat | Cheapest price $216 |
Operator Greyhound | Departure Time 11:25PM | Arrival Time 05:10AM | Duration 30h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $113 |
The table below shows live departures for Indianapolis, IN to San Antonio, TX buses for today, Saturday, November 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus+ · | 3:15 AM Indianapolis, IN | 42h10 | 8:25 PM San Antonio, Avenue A / Pearl Pkwy, TX | 5 transfers | |
FlixBus · FlixBus+ +![]() | 3:15 AM Indianapolis, IN | 34h40 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 3 transfers | |
+ FlixBus+![]() | 4:40 AM Indianapolis, Illinois St (Greyhound Bus Station) | 25h30 | 5:10 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
· · + FlixBus | 11:05 AM Indianapolis, Illinois St (Greyhound Bus Station) | 34h20 | 8:25 PM San Antonio, Avenue A / Pearl Pkwy, TX | 4 transfers | |
· · + FlixBus | 11:05 AM Indianapolis, Illinois St (Greyhound Bus Station) | 34h35 | 8:40 PM San Antonio, Avenue A / Pearl Pkwy, TX | 4 transfers | |
· + FlixBus · FlixBus | 11:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 38h05 | 12:20 AM San Antonio, Avenue A / Pearl Pkwy, TX | 4 transfers | |
· + FlixBus · FlixBus | 11:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 38h15 | 12:30 AM San Antonio, Avenue A / Pearl Pkwy, TX | 4 transfers | |
· +![]() | 11:15 AM Indianapolis, Illinois St (Greyhound Bus Station) | 26h40 | 12:55 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
· +![]() | 4:05 PM Indianapolis, Illinois St (Greyhound Bus Station) | 27h05 | 6:10 PM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
FlixBus+ · | 6:35 PM Indianapolis, IN | 30h30 | 12:05 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
· · | 8:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 28h55 | 12:05 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
FlixBus+ · · | 11:20 PM Indianapolis, IN | 49h00 | 11:20 PM San Antonio, Avenue A / Pearl Pkwy, TX | 5 transfers | |
FlixBus+ · | 11:20 PM Indianapolis, IN | 30h50 | 5:10 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
FlixBus+ · | 11:25 PM Indianapolis, IN | 30h45 | 5:10 AM San Antonio, N St Mary's St (Greyhound), TX | 2 transfers | |
FlixBus+ · · | 11:25 PM Indianapolis, IN | 48h45 | 11:10 PM San Antonio, Avenue A / Pearl Pkwy, TX | 5 transfers | |
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of San Antonio, TX — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio, TX trip today.
A premier collection of Greek, Roman, Egyptian, and Asian art in a striking riverside complex, ideal for art lovers and curious first-time visitors.
This leading Latinx art museum showcases contemporary and historic works, making it one of the city’s most distinctive cultural stops.
Housed in a former brewery, this contemporary art museum presents rotating exhibitions in one of San Antonio’s most atmospheric spaces.
The city’s signature pedestrian corridor links shops, boats, bridges, and historic architecture, making it San Antonio’s essential walking experience.
This artsy, fast-evolving district mixes galleries, murals, boutiques, and nightlife with a strong local identity near the river.
A lively downtown plaza framed by major civic buildings, it is best known for events, fountains, and the nightly cathedral light show nearby.
Puffy tacos are San Antonio’s signature dish: crisp, airy fried corn tortillas filled with picadillo, chicken, or beans, rooted in local Tex-Mex history.
Barbacoa is slow-cooked beef, often served on weekends in breakfast tacos. It is a beloved South Texas tradition with deep Mexican roots.
Breakfast tacos are a daily staple in San Antonio, usually filled with egg, potato, bean, bacon, or chorizo in flour or corn tortillas.
Refined River Walk restaurant serving upscale South Texas and Mexican cuisine. Elegant atmosphere with a long-standing fine dining reputation.
Popular breakfast and lunch spot known for house-made tortillas, tacos, and classic San Antonio Tex-Mex in a relaxed setting.
Beloved market restaurant for authentic Mexican dishes, fresh tortillas, and bakery items. Bustling, traditional atmosphere.
Moderate for a major U.S. city. Hotels and dining are usually cheaper than New York or San Francisco, while car use can add costs because transit is limited.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-$2 per drink or coffee if there is table or bar service.
Official public transport app
UTSA East Campus Lot 1 -> Downtown San Antonio
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Antonio, TX.
Find answers to the most common questions about traveling from Indianapolis, IN to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

Most Indianapolis, IN to San Antonio, TX buses use the Indianapolis, Illinois St (Greyhound Bus Station) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare Indianapolis, IN and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food outlets are available.
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Check bus stations information for Indianapolis, IN and San Antonio, TX, including where buses depart and arrive on this route.
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