- Must visit
San Antonio Museum of Art
Major art museum with collections spanning ancient Mediterranean works, Asian art, Latin American art, and contemporary pieces. Housed in the historic former Lone Star Brewery.
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The cheapest and fastest buses from Indianapolis, IN to San Antonio, TX
Showing times and prices for Jul 02
Cheapest price
$375
Average price
$375
Fastest journey
1 d 8 h 3 m
Average duration
1 d 8 h 3 m
Buses per day
1
Distance
1609 km
Cheap tickets
The best way to find a cheap bus ticket from Indianapolis, IN to San Antonio, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to San Antonio, TX will cost around $375 if you buy it on the day, but the cheapest tickets can be found for only $375.
Fast buses
It's difficult to get from Indianapolis, IN to San Antonio, TX without transferring at least 6 times.
5:15 AM32h03Indianapolis, IN1:18 PMSan Antonio, TX$3751One-way6 transfers
- 5:15 AM32h03Indianapolis, IN1:18 PMSan Antonio, TX$3751One-way6 transfers
Travel Information
Compare bus, flight, and train for Indianapolis, IN to San Antonio, TX
Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $128. For those with little time consider booking a flight which can get you there in 4h 24m. The ticket price range depends on the travel mode: a bus costs an average of $128, and a flight costs an average of $173.
Distance: 999 miles (1609 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$199 Average price Cheapest | $270 Average price | $321 Average price | $230 Average price (fuel + tolls) |
30h 43m Average total duration 30h 13m Onboard + 30m Additional time* | 35h 13m Average total duration 34h 43m Onboard + 30m Additional time* | 7h 24m Average total duration Fastest 4h 24m Onboard + 3h 0m Additional time* | 17h 35m Average total duration (door-to-door) |
 Most popular bus company | Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Indianapolis, IN to San Antonio, TX is a bus with an average price of $199 (€164).
This is compared to other travel options from Indianapolis, IN to San Antonio, TX:
A bus is $70 (€58) less than a train for this route with tickets for a train from Indianapolis, IN to San Antonio, TX costing on average $270 (€222).
A bus is $122 (€100) less than a flight for this route with tickets for a flight from Indianapolis, IN to San Antonio, TX costing on average $321 (€265).
The fastest way to travel from Indianapolis, IN to San Antonio, TX is by flight with an average journey time of 4h 24m.
Other travel options to San Antonio, TX take longer:
Bus takes on average 30h 13m.
Train takes on average 34h 43m.
It's helpful to compare your options as there are 3 ways to travel between Indianapolis, IN and San Antonio, TX including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from Indianapolis, IN to San Antonio, TX among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Indianapolis, IN to San Antonio, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:10AM | Arrival Time 04:55AM | Duration 28h45 | Departure days Thu | Cheapest price $234 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 12:55PM | Duration 34h40 | Departure days Sun | Cheapest price $147 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 11:25PM | Duration 45h10 | Departure days Sun | Cheapest price $144 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 10:00AM | Duration 30h30 | Departure days Sat | Cheapest price $191 |
Operator Greyhound | Departure Time 04:30AM | Arrival Time 05:25AM | Duration 48h55 | Departure days Sun | Cheapest price $207 |
Operator Amtrak Thruway | Departure Time 05:15AM | Arrival Time 01:18PM | Duration 32h03 | Departure days Thu | Cheapest price $375 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 11:25PM | Duration 37h20 | Departure days Sun | Cheapest price $146 |
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:55PM | Duration 26h40 | Departure days Sun | Cheapest price $144 |
Operator Greyhound | Departure Time 04:05PM | Arrival Time 06:10PM | Duration 27h05 | Departure days Sun | Cheapest price $132 |
Operator Greyhound | Departure Time 04:25PM | Arrival Time 06:55PM | Duration 26h30 | Departure days Wed | Cheapest price $300 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 11:55PM | Duration 30h20 | Departure days Sun | Cheapest price $142 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 11:55PM | Duration 28h45 | Departure days Sun | Cheapest price $132 |
Operator Greyhound | Departure Time 11:25PM | Arrival Time 05:00AM | Duration 30h35 | Departure days Sun | Cheapest price $132 |
Live departures
Indianapolis, IN to San Antonio, TX bus times
The table below shows live departures for Indianapolis, IN to San Antonio, TX buses for tomorrow, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 5:15 AM Indianapolis, IN | 32h03 | 1:18 PM San Antonio, TX | 6 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Indianapolis, IN to San Antonio, TX by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Indianapolis, IN to San Antonio, TX buses with Omio?
Greyhound operates all buses services from Indianapolis, IN to San Antonio, TX.
Omio is an official ticket reseller for all your travel options from Indianapolis, IN to San Antonio, TX.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Indianapolis, IN to San Antonio, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Indianapolis, IN to San Antonio, TX.
Journey information
Overview: Bus from Indianapolis, IN to San Antonio, TX
USAUSA
Buses from Indianapolis, IN to San Antonio, TX run on average 9 times per day, taking around 30h 13m. Cheap bus tickets for this journey start at $128 (€106) if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 999 miles (1609 km) distance in 26h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 999 miles (1609 km) |
Average bus duration 30h 13m |
Cheapest ticket price $128 (€106) |
Buses per day 9 |
Fastest bus 26h 30m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 3 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Indianapolis, IN to San Antonio, TXYou can travel by bus between Indianapolis, IN to San Antonio, TX with Greyhound for as low as $128 (€106). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
26h 30m
Cheapest Price
$136 (€112)
Greyhound frequency
8 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Antonio
Things to do in San Antonio
Discover the best of San Antonio — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Antonio trip today.
- Must visit
McNay Art Museum
Renowned museum of modern and contemporary art set in a historic mansion, known for its strong European and American collections and elegant grounds.
- Recommended
The Alamo Exhibit at the Ralston Family Collections Center
Museum galleries next to the Alamo displaying artifacts and interpretation tied to the site’s history. A strong companion visit for understanding San Antonio’s most famous landmark.
- Must visit
San Antonio River Walk
The city’s most iconic walking area, lined with bridges, boats, landscaping, and public art. It is the classic San Antonio experience and especially lively in the evening.
- Recommended
Historic Market Square
Large public market district with strong Mexican cultural identity, colorful surroundings, and frequent events. Popular with both visitors and locals.
- Recommended
La Villita Historic Arts Village
Historic district of preserved buildings and artisan spaces near downtown. It is compact, photogenic, and easy to pair with the River Walk.
- Gluten-free
Puffy Tacos
San Antonio’s signature taco style: a fried masa shell that puffs up, then is filled with beans, meat, lettuce, cheese, and salsa. It is a classic local Tex-Mex specialty strongly associated with the
Breakfast Tacos
A daily staple in San Antonio, usually made with flour tortillas and fillings like egg, potato, bean, bacon, chorizo, and cheese. They are beloved across the city for quick, flavorful breakfasts.
- Gluten-free
Barbacoa
Slow-cooked, tender beef, traditionally served on weekends in tacos with salsa. It is one of the most iconic South Texas breakfast and brunch foods found throughout San Antonio.
Bliss
An established upscale restaurant known for refined New American cooking, polished service, and a more intimate fine-dining experience near Southtown.
The Original Donut Shop
A beloved local breakfast spot best known for oversized breakfast tacos, house-made tortillas, and classic San Antonio morning fare in a casual setting.
Boudro's on the Riverwalk
A well-known River Walk restaurant serving Texas and Southwestern dishes, famous for tableside guacamole and a lively but polished atmosphere.
United States Dollar
Generally cheaper than New York or San Francisco. Hotels vary by season, while dining and transport are usually moderate for U.S. city travel.
Average meal costs
- Budget
- USD 10-15 for tacos, fast food, or casual spots.
- Mid-range
- USD 20-40 per person at a standard restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 4-6 for a latte or cappuccino.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, hotel staff USD 2-5, and round up or tip 10-15% for taxis and rideshares.
VIA goMobile+
Get the appOfficial public transport app
Prices
- Single ticket
- USD 1.30
- Day pass
- USD 2.75
To the city center
University Of Texas At San Antonio East Campus Lot 1, San Antonio -> Centro Plaza, San Antonio
- Distance
- 26 km
- Travel time
- 55 min
- Tap To Ride contactless payment is available on VIA buses, so you can pay with a card or mobile wallet onboard.
- A Day Pass usually pays off after three bus rides in one day and can be bought in the VIA goMobile+ app.
FAQs: Bus from Indianapolis, IN to San Antonio, TX
Find answers to the most common questions about traveling from Indianapolis, IN to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Indianapolis, IN to San Antonio, TX can start from as little as $128 (€106) when you book in advance. The average bus ticket price for Indianapolis, IN to San Antonio, TX is $199 (€164) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Indianapolis, IN to San Antonio, TX is 26h 30m to travel the 999 miles (1609 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Indianapolis, IN to San Antonio, TX leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to San Antonio, TX leaves at 11:30 PM.
There are 9 buses a day from Indianapolis, IN to San Antonio, TX which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Indianapolis, IN to San Antonio, TX, you can count on Greyhound for the best way to get you to San Antonio, TX. You can also check all possible bus companies who offer a service between Indianapolis, IN and San Antonio, TX and compare the amenities they offer before buying a bus ticket.
A trip to San Antonio, TX from Indianapolis, IN is worth doing but not as a day trip with a journey time of 26h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Indianapolis, IN to San Antonio, TX is November.
It's helpful to compare your options as there are 3 ways to travel between Indianapolis, IN and San Antonio, TX including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from Indianapolis, IN to San Antonio, TX:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Indianapolis, IN to San Antonio, TX for bus company Greyhound.
Some of the most interesting sights to explore in San Antonio, TX are:
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
The best things to do in San Antonio, TX include:
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- take a boat tour along the San Antonio River for a unique perspective of the city
- visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from Indianapolis, IN to San Antonio, TX depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Indianapolis, IN to San Antonio, TX.
Yes, the following luggage options are included when booking a bus ticket from Indianapolis, IN to San Antonio, TX:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Indianapolis, IN to San Antonio, TX:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to San Antonio, TX.
You can reserve your seat on the bus from Indianapolis, IN to San Antonio, TX with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Indianapolis, IN to San Antonio, TX with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Indianapolis, IN to San Antonio, TX with the following bus company: Greyhound.
Since neither Indianapolis, IN nor San Antonio, TX are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Indianapolis, IN to San Antonio, TX among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Antonio, TX, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the River Walk and Alamo Plaza. Common scams include overcharging by unofficial taxi services and street vendors. It's advisable to use authorized transportation options and stay alert when approached by strangers offering unsolicited help or tours. Staying in well-lit, busy areas and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Indianapolis, IN to San Antonio, TX
Most Indianapolis, IN to San Antonio, TX buses use the Indianapolis, Illinois St (Greyhound Bus Station) to San Antonio, N St Mary's St (Greyhound) station pair, with some services arriving at San Antonio, Avenue A / Pearl Pkwy. Use this guide to compare Indianapolis, IN and San Antonio, TX bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Indianapolis
Arrival bus stations in San Antonio
Indianapolis, Illinois St (Greyhound Bus Station)
Indianapolis, E Washington St / N Delaware St (City/County Building)
San Antonio, N St Mary's St (Greyhound)
San Antonio, Avenue A / Pearl Pkwy
City-centre transport
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
BusFlixBus 2230 · 11m · $1
10, 14, 214, 9 · 12m · $2 · every ~17 min
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to San Antonio, TX
Here are some other resources that might have the information you need
Most popular buses to and from San Antonio, TX and Indianapolis, IN
Most popular bus connections to San Antonio, TX
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