Travel Information
Compare bus, flight, and train for Indianapolis, IN to San Antonio, TX
Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to San Antonio, TX among Omio's users. If you are prioritising price take the bus with prices starting from $131. For those with little time consider booking a flight which can get you there in 4h 24m. The ticket price range depends on the travel mode: a bus costs an average of $131, and a flight costs an average of $177.
Distance: 999 miles (1609 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$204 Average price Cheapest | $275 Average price | $328 Average price | $235 Average price (fuel + tolls) |
30h 43m Average total duration 30h 13m Onboard + 30m Additional time* | 35h 13m Average total duration 34h 43m Onboard + 30m Additional time* | 7h 24m Average total duration Fastest 4h 24m Onboard + 3h 0m Additional time* | 17h 35m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Indianapolis, IN to San Antonio, TX:
A bus is $72 (€58) less than a train for this route with tickets for a train from Indianapolis, IN to San Antonio, TX costing on average $275 (€222).
A bus is $124 (€100) less than a flight for this route with tickets for a flight from Indianapolis, IN to San Antonio, TX costing on average $328 (€265).
Other travel options to San Antonio, TX take longer:
Bus takes on average 30h 13m.
Train takes on average 34h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Indianapolis, IN to San Antonio, TX Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:10AM | Arrival Time 04:55AM | Duration 28h45 | Departure days Thu | Cheapest price $239 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 12:55PM | Duration 34h40 | Departure days Thu | Cheapest price $252 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 09:10PM | Duration 42h55 | Departure days Thu | Cheapest price $167 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 10:00AM | Duration 30h30 | Departure days Sat | Cheapest price $195 |
Operator Greyhound | Departure Time 04:30AM | Arrival Time 05:25AM | Duration 48h55 | Departure days Sun | Cheapest price $212 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 06:55PM | Duration 34h40 | Departure days Sun | Cheapest price $131 |
Operator Greyhound | Departure Time 11:05AM | Arrival Time 09:10PM | Duration 35h05 | Departure days Thu | Cheapest price $168 |
Operator Greyhound | Departure Time 11:15AM | Arrival Time 12:55PM | Duration 26h40 | Departure days Thu | Cheapest price $225 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 04:25AM | Duration 37h10 | Departure days Sun | Cheapest price $139 |
Operator Greyhound | Departure Time 04:05PM | Arrival Time 05:35PM | Duration 26h30 | Departure days Thu | Cheapest price $178 |
Operator Greyhound | Departure Time 04:25PM | Arrival Time 06:55PM | Duration 26h30 | Departure days Wed | Cheapest price $306 |
Operator Greyhound | Departure Time 06:25PM | Arrival Time 11:55PM | Duration 30h30 | Departure days Thu | Cheapest price $169 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 09:10PM | Duration 50h00 | Departure days Thu | Cheapest price $168 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 09:10PM | Duration 46h40 | Departure days Thu | Cheapest price $168 |
Live departures
Indianapolis, IN to San Antonio, TX bus times
The table below shows live departures for Indianapolis, IN to San Antonio, TX buses for today, Sunday, May 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:15 AM Indianapolis, IN | 34h40 | 6:55 PM San Antonio, TX | 0 transfersDirect | |
![]() | 3:15 PM Indianapolis, IN | 37h10 | 4:25 AM San Antonio, TX | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Indianapolis, IN to San Antonio, TX by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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May 24
Why should you book Indianapolis, IN to San Antonio, TX buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Indianapolis, IN to San Antonio, TX.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Indianapolis, IN to San Antonio, TX.
Journey information
Overview: Bus from Indianapolis, IN to San Antonio, TX
Buses from Indianapolis, IN to San Antonio, TX run on average 9 times per day, taking around 30h 13m. Cheap bus tickets for this journey start at $131 (€106) if you book in advance.
The earliest bus runs at 01:30, the last at 23:30. The fastest bus covers the 999 miles (1609 km) distance in 26h 30m.
Distance 999 miles (1609 km) |
Average bus duration 30h 13m |
Cheapest ticket price $131 (€106) |
Buses per day 9 |
Fastest bus 26h 30m |
First bus 1:30 AM |
Last bus 11:30 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 3 days |
Bus providers: Greyhound from Indianapolis, IN to San Antonio, TXYou can travel by bus between Indianapolis, IN to San Antonio, TX with Greyhound for as low as $131 (€106). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Indianapolis, IN to San Antonio, TX
Find answers to the most common questions about traveling from Indianapolis, IN to San Antonio, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Antonio, TX, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Alamo, a historic Spanish mission and site of the famous 1836 battle for Texan independence
- River Walk, a scenic network of walkways along the San Antonio River lined with shops and restaurants
- San Antonio Missions National Historical Park, a UNESCO World Heritage site preserving four Spanish frontier missions
- San Antonio Museum of Art, housing an extensive collection of art from around the world
- Tower of the Americas, offering panoramic views of the city from its observation deck and revolving restaurant.
- Explore the vibrant Pearl District, known for its trendy shops, restaurants, and farmers market
- take a boat tour along the San Antonio River for a unique perspective of the city
- visit the historic Market Square, a lively Mexican market with shops, food, and entertainment
- enjoy a day at Six Flags Fiesta Texas, an amusement park with thrilling rides and shows
- experience the San Antonio Zoo, home to a wide variety of animals and interactive exhibits.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Indianapolis, IN to San Antonio, TX
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to San Antonio, TX
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