Indianapolis, IN to San Francisco, CA bus with Greyhound

Thu, May 07
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The cheapest and fastest buses from Indianapolis, IN to San Francisco, CA

Showing times and prices for May 07

Cheapest price

$235

Average price

$262

Fastest journey

2 d 4 h 20 m

Average duration

2 d 7 h 45 m

Buses per day

10

Distance

3130 km

Cheap tickets

The best way to find a cheap bus ticket from Indianapolis, IN to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Indianapolis, IN to San Francisco, CA will cost around $262 if you buy it on the day, but the cheapest tickets can be found for only $235.

Fast buses

It's difficult to get from Indianapolis, IN to San Francisco, CA without transferring at least 3 times.

  • FlixBusFlixBus+Greyhoundundefined · undefined · undefined
    11:30 PM63h55
    Indianapolis, E Washington St / N Delaware St (City/County Building), IN
    12:25 PMSan Francisco, Transit Center Bay 29
    $2351One-way
    4 transfers
  • FlixBusFlixBus+Greyhoundundefined · undefined+FlixBusFlixBus
    11:30 PM69h20
    Indianapolis, E Washington St / N Delaware St (City/County Building), IN
    5:50 PMSan Francisco, Townsend Street / 5th Street, CA
    $2371One-way
    3 transfers
  • Greyhoundundefined · undefined · undefined · undefined
    11:05 AM52h20
    Indianapolis, Illinois St (Greyhound Bus Station)
    12:25 PMSan Francisco, Transit Center Bay 29
    $2441One-way
    3 transfers
  • FlixBusFlixBus+Greyhoundundefined · undefined · undefined
    6:25 PM63h50
    Indianapolis, E Washington St / N Delaware St (City/County Building), IN
    7:15 AMSan Francisco, Transit Center Bay 29
    $2581One-way
    4 transfers
  • FlixBusFlixBus+Greyhoundundefined · undefined · undefined
    9:30 AM53h55
    Indianapolis, E Washington St / N Delaware St (City/County Building), IN
    12:25 PMSan Francisco, Transit Center Bay 29
    $2601One-way
    3 transfers

Travel Information

Compare bus, train, and flight for Indianapolis, IN to San Francisco, CA

Omio recommends booking the train as it is the most popular option from Indianapolis, IN to San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from $161. For those with little time consider booking a flight which can get you there in 6h 40m. The ticket price range depends on the travel mode: a flight costs an average of $161, and a train costs an average of $209.

Distance: 1944 miles (3130 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$388

Average price

$680

Average price

$372

Average price

Cheapest

$474

Average price

(fuel + tolls)

57h 5m

Average total duration

56h 35m

Onboard

+

30m

Additional time*

58h 33m

Average total duration

58h 3m

Onboard

+

30m

Additional time*

9h 40m

Average total duration

Fastest

6h 40m

Onboard

+

3h 0m

Additional time*

33h 2m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Amtrak

Most popular train company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Indianapolis, IN to San Francisco, CA is a flight with an average price of $372 (€297).

This is compared to other travel options from Indianapolis, IN to San Francisco, CA:

A flight is $16 (€13) less than a bus for this route with tickets for a bus from Indianapolis, IN to San Francisco, CA costing on average $388 (€310).

A flight is $308 (€246) less than a train for this route with tickets for a train from Indianapolis, IN to San Francisco, CA costing on average $680 (€544).

The fastest way to travel from Indianapolis, IN to San Francisco, CA is by flight with an average journey time of 6h 40m.

Other travel options to San Francisco, CA take longer:

Bus takes on average 56h 35m.

Train takes on average 58h 3m.

It's helpful to compare your options as there are 3 ways to travel between Indianapolis, IN and San Francisco, CA including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Indianapolis, IN to San Francisco, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Indianapolis, IN to San Francisco, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
05:00AM
Arrival Time
07:15AM
Duration
53h15
Departure days
Everyday
Cheapest price
$220
Operator
Greyhound
Departure Time
08:35AM
Arrival Time
12:25PM
Duration
54h50
Departure days
Tue
Cheapest price
$193
Operator
Greyhound
Departure Time
09:30AM
Arrival Time
12:25PM
Duration
53h55
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$257
Operator
Greyhound
Departure Time
11:05AM
Arrival Time
12:25PM
Duration
52h20
Departure days
Everyday
Cheapest price
$201
Operator
Greyhound
Departure Time
06:25PM
Arrival Time
07:15AM
Duration
63h50
Departure days
Everyday
Cheapest price
$249
Operator
Greyhound
Departure Time
08:05PM
Arrival Time
07:15AM
Duration
62h10
Departure days
Everyday
Cheapest price
$233
Operator
Greyhound
Departure Time
11:30PM
Arrival Time
12:25PM
Duration
63h55
Departure days
Everyday
Cheapest price
$190

Live departures

Indianapolis, IN to San Francisco, CA bus times

The table below shows live departures for Indianapolis, IN to San Francisco, CA buses for today, Wednesday, May 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus+greyhoundundefined · undefined · undefined6:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN
63h50
7:15 AM San Francisco, Transit Center Bay 294 transfers
meinfernbus_flixbusFlixBus+greyhoundundefined · undefined · undefined6:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN
67h40
11:05 AM San Francisco, Townsend Street / 5th Street, CA5 transfers
greyhoundundefined · undefined · undefined · undefined8:05 PM Indianapolis, Illinois St (Greyhound Bus Station)
66h00
11:05 AM San Francisco, Townsend Street / 5th Street, CA4 transfers
greyhoundundefined · undefined · undefined · undefined8:05 PM Indianapolis, Illinois St (Greyhound Bus Station)
62h10
7:15 AM San Francisco, Transit Center Bay 293 transfers
meinfernbus_flixbusFlixBus+greyhoundundefined · undefined · undefined11:30 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN
63h55
12:25 PM San Francisco, Transit Center Bay 294 transfers
greyhoundundefined · undefined · undefined · undefined5:00 AM Indianapolis, Illinois St (Greyhound Bus Station)
53h15
7:15 AM San Francisco, Transit Center Bay 293 transfers
greyhoundundefined · undefined · undefined · undefined5:00 AM Indianapolis, Illinois St (Greyhound Bus Station)
57h05
11:05 AM San Francisco, Townsend Street / 5th Street, CA4 transfers
meinfernbus_flixbusFlixBus+greyhoundundefined · undefined · undefined9:30 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN
53h55
12:25 PM San Francisco, Transit Center Bay 293 transfers
greyhoundundefined · undefined · undefined · undefined11:05 AM Indianapolis, Illinois St (Greyhound Bus Station)
52h20
12:25 PM San Francisco, Transit Center Bay 293 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Indianapolis, IN to San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
May 07
Fri
May 08
Sat
May 09
Sun
May 10
Mon
May 11
Tue
May 12
Wed
May 13

Why should you book Indianapolis, IN to San Francisco, CA buses with Omio?

Greyhound operates all buses services from Indianapolis, IN to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Indianapolis, IN to San Francisco, CA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Indianapolis, IN to San Francisco, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Indianapolis, IN to San Francisco, CA.

Journey information

Overview: Bus from Indianapolis, IN to San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from Indianapolis, IN to San Francisco, CA run on average 10 times per day, taking around 56h 35m. Cheap bus tickets for this journey start at $142 (€114) if you book in advance.

The earliest bus runs at 03:15, the last at 23:55. The fastest bus covers the 1944 miles (3130 km) distance in 52h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1944 miles (3130 km)
Average bus duration
56h 35m
Cheapest ticket price
$142 (€114)
Buses per day
10
Fastest bus
52h 0m
First bus
3:15 AM
Last bus
11:55 PM
Cheapest Month
Jul
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Indianapolis, IN to San Francisco, CAYou can travel by bus between Indianapolis, IN to San Francisco, CA with Greyhound for as low as $142 (€114). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
52h 0m
Cheapest Price
$142 (€114)
Greyhound frequency
10 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Indianapolis, IN to San Francisco, CA

Find answers to the most common questions about traveling from Indianapolis, IN to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Indianapolis, IN to San Francisco, CA can start from as little as $142 (€114) when you book in advance. The average bus ticket price for Indianapolis, IN to San Francisco, CA is $388 (€310) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Indianapolis, IN to San Francisco, CA is 52h 0m to travel the 1944 miles (3130 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Indianapolis, IN to San Francisco, CA leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to San Francisco, CA leaves at 11:55 PM.
There are 10 buses a day from Indianapolis, IN to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Indianapolis, IN to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between Indianapolis, IN and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
A trip to San Francisco, CA from Indianapolis, IN is worth doing but not as a day trip with a journey time of 52h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Indianapolis, IN to San Francisco, CA is July.
It's helpful to compare your options as there are 3 ways to travel between Indianapolis, IN and San Francisco, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Indianapolis, IN to San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Indianapolis, IN to San Francisco, CA for bus company Greyhound.
Some of the most interesting sights to explore in San Francisco, CA are:
  • Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
  • Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
  • Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
  • Golden Gate Park, a large urban park with gardens, museums, and recreational activities
  • Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
  • Ride a cable car through the steep streets of San Francisco for a classic city experience
  • Explore the vibrant murals and street art in the Mission District
  • Visit the Exploratorium, an interactive science museum perfect for all ages
  • Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
  • Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Indianapolis, IN to San Francisco, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Indianapolis, IN to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Indianapolis, IN to San Francisco, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Indianapolis, IN to San Francisco, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to San Francisco, CA.
You can reserve your seat on the bus from Indianapolis, IN to San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Indianapolis, IN to San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Indianapolis, IN to San Francisco, CA with the following bus company: Greyhound.
Since neither Indianapolis, IN nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Indianapolis, IN to San Francisco, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Indianapolis, IN to San Francisco, CA

Indianapolis
San Francisco
The major bus station for departures in Indianapolis is Indianapolis, E Washington St / N Delaware St (City/County Building). Find all the information you need to know about services, amenities and connections at Indianapolis, E Washington St / N Delaware St (City/County Building) for your trip from Indianapolis to San Francisco.
Indianapolis, E Washington St / N Delaware St (City/County Building)
information
Indianapolis, Illinois St (Greyhound Bus Station)
information

Most popular buses to and from San Francisco, CA and Indianapolis, IN

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