- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
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The cheapest and fastest buses from Indianapolis, IN to San Francisco, CA
Showing times and prices for Aug 06
Cheapest price
$319
Average price
$446
Fastest journey
2 d 4 h
Average duration
2 d 10 h 40 m
Buses per day
4
Distance
3130 km
Cheap tickets
The best way to find a cheap bus ticket from Indianapolis, IN to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to San Francisco, CA will cost around $446 if you buy it on the day, but the cheapest tickets can be found for only $319.
Fast buses
Of the 4 buses that leave Indianapolis, IN for San Francisco, CA on Thu, Aug 06, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 3130 km distance in an average of 2 d 10 h 40 m but if you time it right, some buses will get you there in just 2 d 4 h .
On Thu, Aug 06 the slowest buses will take 2 d 15 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:35 PM54h50Indianapolis, IN8:25 PMSan Francisco, CA$3191One-way0 transfers- 4:25 PM52h00Indianapolis, IN8:25 PMSan Francisco, CA$4111One-way0 transfers
- 3:30 AM63h55Indianapolis, IN7:25 PMSan Francisco, CA$4811One-way0 transfers
- 4:30 AM63h55Indianapolis, IN8:25 PMSan Francisco, CA$5731One-way0 transfers
- 4:25 PM52h00Indianapolis, IN8:25 PMSan Francisco, CA$4111One-way0 transfers
- 1:35 PM54h50Indianapolis, IN8:25 PMSan Francisco, CA$3191One-way0 transfers
- 4:30 AM63h55Indianapolis, IN8:25 PMSan Francisco, CA$5731One-way0 transfers
- 3:30 AM63h55Indianapolis, IN7:25 PMSan Francisco, CA$4811One-way0 transfers
Journey information
Overview: Bus from Indianapolis, IN to San Francisco, CA
USAUSA
Buses from Indianapolis, IN to San Francisco, CA run on average 10 times per day, taking around 54h 30m. Cheap bus tickets for this journey start at $133 if you book in advance.
The earliest bus runs at 03:15, the last at 23:30. The fastest bus covers the 1944 miles (3130 km) distance in 52h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1944 miles (3130 km) |
Average bus duration 54h 30m |
Cheapest ticket price $133 |
Buses per day 10 |
Fastest bus 52h 0m |
First bus 3:15 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Indianapolis, IN to San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 03:15PM | Duration 62h10 | Departure days Thu, Sun | Cheapest price $551 |
Operator Greyhound | Departure Time 02:35AM | Arrival Time 08:25PM | Duration 65h50 | Departure days Wed | Cheapest price $580 |
Operator Greyhound | Departure Time 03:30AM | Arrival Time 07:25PM | Duration 63h55 | Departure days Thu, Fri, Sat, Sun | Cheapest price $263 |
Operator Greyhound | Departure Time 04:30AM | Arrival Time 08:25PM | Duration 63h55 | Departure days Tue, Fri | Cheapest price $495 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 02:15PM | Duration 53h15 | Departure days Mon | Cheapest price $535 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 03:15PM | Duration 53h15 | Departure days Fri | Cheapest price $175 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 07:25PM | Duration 53h55 | Departure days Mon | Cheapest price $404 |
Operator Greyhound | Departure Time 01:35PM | Arrival Time 02:05AM | Duration 60h30 | Departure days Thu, Sat, Sun | Cheapest price $144 |
Operator Greyhound | Departure Time 03:05PM | Arrival Time 07:25PM | Duration 52h20 | Departure days Tue | Cheapest price $234 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 07:25PM | Duration 52h10 | Departure days Wed, Sun | Cheapest price $176 |
Operator Greyhound | Departure Time 04:25PM | Arrival Time 08:25PM | Duration 52h00 | Departure days Tue, Wed, Thu, Fri | Cheapest price $320 |
Operator Greyhound | Departure Time 07:05PM | Arrival Time 01:40PM | Duration 66h35 | Departure days Mon, Fri | Cheapest price $133 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 03:15PM | Duration 67h10 | Departure days Sat | Cheapest price $260 |
Operator Greyhound | Departure Time 11:25PM | Arrival Time 03:15PM | Duration 63h50 | Departure days Sun | Cheapest price $140 |
Live departures
Indianapolis, IN to San Francisco, CA bus times
The table below shows live departures for Indianapolis, IN to San Francisco, CA buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 3:15 PM Indianapolis, IN | 52h10 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
| 4:25 PM Indianapolis, IN | 52h00 | 8:25 PM San Francisco, CA | 0 transfersDirect | |
| Thursday, August 6 | |||||
| 3:30 AM Indianapolis, IN | 63h55 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Indianapolis, IN to San Francisco, CA buses with Omio?
Greyhound operates all buses services from Indianapolis, IN to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Indianapolis, IN to San Francisco, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Indianapolis, IN to San Francisco, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Indianapolis, IN to San Francisco, CA.
Bus providers: Greyhound from Indianapolis, IN to San Francisco, CAYou can travel by bus between Indianapolis, IN to San Francisco, CA with Greyhound for as low as $133. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
52h 0m
Cheapest Price
$133
Greyhound frequency
9 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Francisco, CA
Things to do in San Francisco, CA
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
- Must visit
de Young Museum
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
- Must visit
San Francisco Museum of Modern Art
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
- Must visit
Golden Gate Park
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
- Must visit
Lombard Street
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
- Must visit
The Embarcadero
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
- Vegetarian
- Vegan
San Francisco Sourdough
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
- Gluten-free
Dungeness Crab
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
Cioppino
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Benu
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Sotto Mare
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
La Taqueria
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
US Dollar ($)
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Average meal costs
- Budget
- $12-20 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $90+ per person for upscale dining.
- Coffee
- $4-7 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
FAQs: Bus from Indianapolis, IN to San Francisco, CA
Find answers to the most common questions about traveling from Indianapolis, IN to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Indianapolis, IN to San Francisco, CA can start from as little as $133 when you book in advance. The average bus ticket price for Indianapolis, IN to San Francisco, CA is $365 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Indianapolis, IN to San Francisco, CA is 52h 0m to travel the 1944 miles (3130 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Indianapolis, IN to San Francisco, CA leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to San Francisco, CA leaves at 11:30 PM.
There are 10 buses a day from Indianapolis, IN to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Indianapolis, IN to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between Indianapolis, IN and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
When departing from Indianapolis, IN , you have various bus station options to start your journey from including Indianapolis, E Washington St / N Delaware St (City/County Building), IN, Indianapolis, Illinois St (Greyhound Bus Station) . When arriving in San Francisco, CA , you can end your journey in bus stations like San Francisco, Transit Center Bay 29, San Francisco, Townsend Street / 5th Street, CA .Passengers board the bus most frequently from Indianapolis, E Washington St / N Delaware St (City/County Building), IN, which is located around away from the city centre, and they get off the bus at San Francisco, Transit Center Bay 29, located 2 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Indianapolis, IN and San Francisco, CA including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Indianapolis, IN to San Francisco, CA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Indianapolis, IN to San Francisco, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Indianapolis, IN to San Francisco, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Indianapolis, IN to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Indianapolis, IN to San Francisco, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Indianapolis, IN to San Francisco, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to San Francisco, CA.
You can reserve your seat on the bus from Indianapolis, IN to San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Indianapolis, IN to San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Indianapolis, IN to San Francisco, CA with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Indianapolis, IN to San Francisco, CA
Most Indianapolis, IN to San Francisco, CA buses use the Indianapolis, Illinois St (Greyhound Bus Station) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Indianapolis, IN and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Indianapolis
Arrival bus stations in San Francisco
Which Indianapolis, IN station do buses to San Francisco, CA leave from?
Buses from Indianapolis, IN to San Francisco, CA leave from Indianapolis, E Washington St / N Delaware St (City/County Building). The station is from Indianapolis, IN city centre at Indianapolis City-County Building, N Pennsylvania St, Indianapolis, IN 46204, USA.
Indianapolis, E Washington St / N Delaware St (City/County Building)Indianapolis City-County Building, N Pennsylvania St, Indianapolis, IN 46204, USA
City-centre transport
Getting to Indianapolis, E Washington St / N Delaware St (City/County Building) from Indianapolis city centre
TRUE
Indianapolis, E Washington St / N Delaware St (City/County Building) bus station facilities and services
Indianapolis, E Washington St / N Delaware St (City/County Building) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Indianapolis, E Washington St / N Delaware St (City/County Building). ATMs are available at Indianapolis, E Washington St / N Delaware St (City/County Building).
Tickets and information
Ticket office support is available at Indianapolis, E Washington St / N Delaware St (City/County Building).
Parking, taxis and toilets
Available at Indianapolis, E Washington St / N Delaware St (City/County Building): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, E Washington St / N Delaware St (City/County Building): Wheelchair accessible buses available.
Indianapolis, Illinois St (Greyhound Bus Station)350 S Illinois St, Indianapolis, IN 46225, USA
City-centre transport
Getting to Indianapolis, Illinois St (Greyhound Bus Station) from Indianapolis city centre
TRUE
Indianapolis, Illinois St (Greyhound Bus Station) bus station facilities and services
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Tickets and information
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Which San Francisco, CA station do buses from Indianapolis, IN arrive at?
Buses from Indianapolis, IN to San Francisco, CA most often arrive at San Francisco, Transit Center Bay 29. Some services arrive at San Francisco, Townsend Street / 5th Street, so check your ticket before travel to confirm your San Francisco, CA arrival station.
San Francisco, Transit Center Bay 29Transit Center Bay 29, San Francisco, CA 94105, USA
City-centre transport
Getting to San Francisco, Transit Center Bay 29 from San Francisco city centre
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
Bus397 · 8m · $2
14, 14R · 13m · $2 · every ~30 min
101, 120 · 14m · $6 · every ~9 min
7 · 21m · $2 · every ~10 min
SubwayYellow-N, Green-N, Red-N, Blue-N · 10m · $2 · every ~27 min
San Francisco, Transit Center Bay 29 bus station facilities and services
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Tickets and information
Ticket office support is available at San Francisco, Transit Center Bay 29.
Parking, taxis and toilets
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
San Francisco, Townsend Street / 5th StreetSan Francisco Bus Station,401 Townsend St,94107
City-centre transport
Getting to San Francisco, Townsend Street / 5th Street from San Francisco city centre
BusEast, West · 20m · every ~4 min
Nbus, Nowl · 24m · $2 · every ~2 min
TramN · 23m · $2 · every ~11 min
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to San Francisco, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Francisco, CA and Indianapolis, IN
Most popular bus connections to San Francisco, CA
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