Florence, SC to Syracuse, NY bus with Greyhound

Sun, Nov 01
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Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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Journey information

Overview: Bus from Florence, SC to Syracuse, NY

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Buses from Florence, SC to Syracuse, NY run on average 2 times per day, taking around 21h 55m. Cheap bus tickets for this journey start at $96 (€80) if you book in advance.

The earliest bus runs at 00:05, the last at 21:00. The fastest bus covers the 641 miles (1033 km) distance in 17h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
641 miles (1033 km)
Average bus duration
21h 55m
Cheapest ticket price
$96 (€80)
Buses per day
2
Fastest bus
17h 40m
First bus
12:05 AM
Last bus
9:00 PM
Cheapest Month
Nov
Cheapest Day
Fri
High Season
Jul - Sep
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Frequently asked questions about your Florence, SC to Syracuse, NY trip

Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Florence, SC to Syracuse, NY.

Cheap bus tickets from Florence, SC to Syracuse, NY can start from as little as $96 (€80) when you book in advance. The average bus ticket price for Florence, SC to Syracuse, NY is $169 (€141) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Florence, SC to Syracuse, NY leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Syracuse, NY leaves at 9:00 PM.
There are 2 buses a day from Florence, SC to Syracuse, NY which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.

Why should you book Florence, SC to Syracuse, NY buses with Omio?

Greyhound as well as FlixBus offer buses services from Florence, SC to Syracuse, NY.
Omio is an official ticket reseller for all your travel options from Florence, SC to Syracuse, NY.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Syracuse, NY.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence, SC to Syracuse, NY.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Florence, SC to Syracuse, NY.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence, SC to Syracuse, NY.

Bus providers: Greyhound, FlixBus from Florence, SC to Syracuse, NYYou can travel by bus between Florence, SC to Syracuse, NY with Greyhound, FlixBus for as low as $96 (€80). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
17h 40m
Cheapest FlixBus Price
$131 (€109)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
24h 45m
Cheapest Greyhound Price
$96 (€80)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Companies, tickets, and onboard amenities between Florence, SC and Syracuse, NY

Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.

When taking a bus from Florence, SC to Syracuse, NY, you can count on Greyhound, FlixBus for the best way to get you to Syracuse, NY. You can also check all possible bus companies who offer a service between Florence, SC and Syracuse, NY and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Florence, SC to Syracuse, NY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Florence, SC to Syracuse, NY for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Florence, SC to Syracuse, NY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Florence, SC to Syracuse, NY.
Yes, the following luggage options are included when booking a bus ticket from Florence, SC to Syracuse, NY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Florence, SC to Syracuse, NY:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Florence, SC to Syracuse, NY. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Florence, SC to Syracuse, NY with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Florence, SC to Syracuse, NY with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Florence, SC to Syracuse, NY with the following bus company: Greyhound, FlixBus.

Complete guide to Syracuse, NY

Things to do in Syracuse, NY

Discover the best of Syracuse, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse, NY trip today.

  • Must visit

Everson Museum of Art

Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.

  • Must visit

Erie Canal Museum

Historic house museum preserving nineteenth-century Syracuse domestic life. Worth visiting for period rooms and insight into early city society.

  • Recommended

Museum of Science and Technology

Interactive museum focused on science and technology, famous for hands-on exhibits and domed IMAX theater. Great for families and curious visitors.

United States Dollar ($)

Moderate for a U.S. city. Hotels are often cheaper than NYC, dining is mid-priced, and most visitors need a car or rideshares as transit is limited.

Average meal costs

Budget
$10-15 for fast food or casual lunch.
Mid-range
$18-35 per person for a restaurant meal.
Fine dining
$50+ per person for upscale dining.
Coffee
$3-5 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.

Plan your visit to Syracuse, NY

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Syracuse, NY.

The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Syracuse, NY, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by taxis or ride services and fraudulent ticket sales for local events. It's advisable to use authorized transportation providers and remain vigilant when handling cash or personal belongings.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Bus from Florence, SC to Syracuse, NY

Find answers to the most common questions about traveling from Florence, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

FAQs
It's helpful to compare your options as there are 2 ways to travel between Florence, SC and Syracuse, NY including taking a train and bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

popular bus stations

Popular bus stations from Florence, SC to Syracuse, NY

Most Florence, SC to Syracuse, NY buses use the Florence, W Lucas St (TA Gas Station) to Syracuse, Walsh Cir (Syracuse Bus Station) station pair. Use this guide to compare Florence, SC and Syracuse, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Florence
Arrival bus stations in Syracuse

Which Florence, SC station do buses to Syracuse, NY leave from?

Buses from Florence, SC to Syracuse, NY leave from Florence, W Lucas St (TA Gas Station). The station is 3 miles (6 km) from Florence, SC city centre at Florence, SC, USA.
Florence, W Lucas St (TA Gas Station)Florence, SC, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre

Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:

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Florence, W Lucas St (TA Gas Station) bus station facilities and services

Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Food and snacks available at the gas station.

Wi-Fi and ATMs

Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).

Tickets and information

Ticket office support is available at Florence, W Lucas St (TA Gas Station).

Parking, taxis and toilets

Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.

Bus stations for Florence, SC to Syracuse, NY

Check bus stations information for Florence, SC and Syracuse, NY, including where buses depart and arrive on this route.

Passengers board the bus most frequently from Florence, W Lucas St (TA Gas Station), which is located around 3 miles (6 km) away from the city centre, and they get off the bus at Syracuse, Walsh Cir (Syracuse Bus Station), located 4 away from the city centre.

More options for your journey from Florence, SC to Syracuse, NY

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Syracuse, NYFlorence, SC to Syracuse, NY bus

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