Florence, SC to Syracuse, NY bus

Sat, May 02
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Travel Information

Compare train for Florence, SC to Syracuse, NY

Omio recommends booking the train as it is the most popular option from Florence, SC to Syracuse, NY among Omio's users. If you are prioritising price take the train with prices starting from $317. For those with little time consider booking a train which can get you there in 22h 52m. The ticket price range depends on the travel mode: a train costs an average of $317, and a train costs an average of $317.

Distance: 641 miles (1033 km)

Compare train with

Most popular
Train

$365

Average price

Cheapest

23h 22m

Average total duration

Fastest

22h 52m

Onboard

+

30m

Additional time*

Direct Options

Compare prices and tickets Florence, SC to Syracuse, NY by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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May 02
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May 03
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May 04
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May 08

Journey information

Overview: Bus from Florence, SC to Syracuse, NY

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Take a bus from Florence, SC to Syracuse, NY and enjoy the approximately 641 miles (1033 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:05, the last at 21:00.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $317 (€254)
Distance
641 miles (1033 km)
Buses per day
4
First bus
12:05 AM
Last bus
9:00 PM
Cheapest Month
Jul
Cheapest Day
Fri
High Season
Oct - Dec
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $317 (€254)

FAQs: Bus from Florence, SC to Syracuse, NY

Find answers to the most common questions about traveling from Florence, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Florence, SC to Syracuse, NY leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Florence, SC to Syracuse, NY leaves at 9:00 PM.
The cheapest month for a bus from Florence, SC to Syracuse, NY is July.
Yes, you can take a train between Florence, SC and Syracuse, NY.
No, the bus from Florence, SC to Syracuse, NY has no accessibility options.
No, there are no bathrooms on board the bus from Florence, SC to Syracuse, NY.
No, bikes are not allowed on board the bus from Florence, SC to Syracuse, NY.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Florence, SC to Syracuse, NY.
No, luggage for the bus from Florence, SC to Syracuse, NY needs to be booked in addition.
No, there are no additional luggage options for the bus from Florence, SC to Syracuse, NY.
Unfortunately, pets are not allowed on the bus from Florence, SC to Syracuse, NY.
No, there are no USB plugs on board the bus from Florence, SC to Syracuse, NY.
No, there is no WiFi on board the bus from Florence, SC to Syracuse, NY.
Since neither Florence, SC nor Syracuse, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Florence, SC to Syracuse, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Syracuse, NY, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by taxis or ride services and fraudulent ticket sales for local events. It's advisable to use authorized transportation providers and remain vigilant when handling cash or personal belongings.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Florence, SC to Syracuse, NY

Florence
Syracuse
The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Syracuse.
Florence, S Irby St (Greyhound Bus Stop)
information

More options for your journey from Florence, SC to Syracuse, NY

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Return journeys for buses from Syracuse, NY to Florence, SC
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