Florence, SC to Syracuse, NY bus

Thu, Nov 27
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Compare prices and tickets Florence, SC to Syracuse, NY by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Nov 27
Fri
Nov 28
Sat
Nov 29
Sun
Nov 30
Mon
Dec 01
Tue
Dec 02
Wed
Dec 03

Journey information

Overview: Bus from Florence, SC to Syracuse, NY

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Take a bus from Florence, SC to Syracuse, NY and enjoy the approximately 641 miles (1033 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:05, the last at 21:00.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $317 (€257)
Distance
641 miles (1033 km)
Buses per day
2
First bus
00:05
Last bus
21:00
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $317 (€257)

FAQs: Bus from Florence, SC to Syracuse, NY

Find answers to the most common questions about traveling from Florence, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

FAQs
The first bus from Florence, SC to Syracuse, NY leaves at 9: 25AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Florence, SC to Syracuse, NY leaves at 11: 50PM.
A day trip to Syracuse, NY from Florence, SC is worth doing with a journey time of min each way. Check with Omio app   the best way to travel.
Yes, you can take a train to Syracuse, NY from Florence, SC.
No, the bus from Florence, SC to Syracuse, NY has no accessibility options.
No, there are no bathrooms on board the bus from Florence, SC to Syracuse, NY.
No, bikes are not allowed on board the bus from Florence, SC to Syracuse, NY.

To find the cheapest bus tickets for your trip from Florence, SC to Syracuse, NY, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Florence, SC to Syracuse, NY.
    No, luggage for the bus from Florence, SC to Syracuse, NY needs to be booked in addition.
    No, there are no additional luggage options for the bus from Florence, SC to Syracuse, NY.
    Unfortunately, pets are not allowed on the bus from Florence, SC to Syracuse, NY.
    No, there are no USB plugs on board the bus from Florence, SC to Syracuse, NY.
    No, there is no WiFi on board the bus from Florence, SC to Syracuse, NY.

    popular bus stations

    Popular bus stations from Florence, SC to Syracuse, NY

    Florence
    Syracuse
    The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Syracuse.
    Florence, S Irby St (Greyhound Bus Stop)
    information

    More options for your journey from Florence, SC to Syracuse, NY

    Here are some other resources that might have the information you need

    Return journeys for buses from Syracuse, NY to Florence, SC
    Tickets and more information for coaches to Florence, SC
    Tickets and more information for coaches to Syracuse, NY

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