FLORENCE to SYRACUSE bus from $314 (€254) with Omio

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Compare prices and tickets Florence, SC to Syracuse, NY by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Florence, SC to Syracuse, NY

USA

Take a bus from Florence, SC to Syracuse, NY and enjoy the approximately 641 miles (1033 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:05, the last at 21:00.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.

Price information

Cheapest alternative travel mode

Train from $314 (€254)

Distance

641 miles (1033 km)

Buses per day

First bus

00:05

Last bus

21:00

Cheapest month

Jul

Cheapest day

Fri

High season

Oct - Dec

Low season

Jul - Sep

Price information

Cheapest alternative travel mode

Train from $314 (€254)

FAQs: Bus from Florence, SC to Syracuse, NY

Find answers to the most common questions about traveling from Florence, SC to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

The earliest bus from Florence, SC to Syracuse, NY leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.

The latest bus from Florence, SC to Syracuse, NY leaves at 9:00 PM.

The cheapest month for a bus from Florence, SC to Syracuse, NY is July.

Yes, you can take a train between Florence, SC and Syracuse, NY.

No, there are no bathrooms on board the bus from Florence, SC to Syracuse, NY.

No, the bus from Florence, SC to Syracuse, NY has no accessibility options.

No, bikes are not allowed on board the bus from Florence, SC to Syracuse, NY.

Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

No, there is no food available to purchase on board the bus from Florence, SC to Syracuse, NY.

No, luggage for the bus from Florence, SC to Syracuse, NY needs to be booked in addition.

No, there are no additional luggage options for the bus from Florence, SC to Syracuse, NY.

Unfortunately, pets are not allowed on the bus from Florence, SC to Syracuse, NY.

No, there are no USB plugs on board the bus from Florence, SC to Syracuse, NY.

No, there is no WiFi on board the bus from Florence, SC to Syracuse, NY.

popular bus stations

Popular bus stations from Florence, SC to Syracuse, NY

Florence

Syracuse

The major bus station for departures in Florence is Florence, S Irby St (Greyhound Bus Stop). Find all the information you need to know about services, amenities and connections at Florence, S Irby St (Greyhound Bus Stop) for your trip from Florence to Syracuse.

Florence, S Irby St (Greyhound Bus Stop)

information

Most popular bus connections from Florence, SC

Bus Florence, SC - Raleigh, NC

More options for your journey from Florence, SC to Syracuse, NY

Here are some other resources that might have the information you need

Return journeys for buses from Syracuse, NY to Florence, SC

Tickets and more information for coaches to Florence, SC

Tickets and more information for coaches to Syracuse, NY

Most popular buses to and from Syracuse, NY and Florence, SC

Bus Florence, SC - New York, NY

Bus Florence, SC - Chicago, IL

Bus Florence, SC - Los Angeles, CA

Bus Florence, SC - Washington, DC

Bus Florence, SC - Philadelphia, PA

Bus Florence, SC - Orlando, FL

Bus Florence, SC - Atlanta, GA

Bus Florence, SC - Miami, FL

Bus Florence, SC - Las Vegas, NV

Bus Florence, SC - Tampa, FL

Bus Florence, SC - Baltimore, MD

Bus Florence, SC - New Orleans, LA

Bus Florence, SC - Charlotte, NC

Bus Florence, SC - Nashville, TN

Bus Florence, SC - Raleigh, NC

Bus Florence, SC - Cleveland, OH

Bus Florence, SC - Richmond, VA

Bus Florence, SC - Memphis, TN

Bus Florence, SC - Harrisburg, PA

Bus Florence, SC - Wilmington, DE

Bus Florence, SC - Louisville, KY

Bus Florence, SC - Fayetteville, NC

Bus Boston, MA - Syracuse, NY

Bus New York, NY - Syracuse, NY

Bus Chicago, IL - Syracuse, NY

Bus Los Angeles, CA - Syracuse, NY

Bus Washington, DC - Syracuse, NY

Bus Philadelphia, PA - Syracuse, NY

Bus Orlando, FL - Syracuse, NY

Bus Dallas, TX - Syracuse, NY

Bus Atlanta, GA - Syracuse, NY

Bus Miami, FL - Syracuse, NY

Bus Baltimore, MD - Syracuse, NY

Bus Newark, NJ - Syracuse, NY

Bus Denver, CO - Syracuse, NY

Bus Charlotte, NC - Syracuse, NY

Bus Raleigh, NC - Syracuse, NY

Bus Pittsburgh, PA - Syracuse, NY

Bus Cleveland, OH - Syracuse, NY

Bus Detroit, MI - Syracuse, NY

Bus Toronto, ON - Syracuse, NY

Bus Minneapolis, MN - Syracuse, NY

Bus Hartford, CT - Syracuse, NY

Bus Norfolk, VA - Syracuse, NY

Most popular bus connections to Syracuse, NY

Bus New York, NY - Syracuse, NY

Bus Newark, NJ - Syracuse, NY

Bus Boston, MA - Syracuse, NY

Bus Montreal, QC - Syracuse, NY

Bus Rochester, NY - Syracuse, NY

Bus Ithaca, NY - Syracuse, NY

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Florence, SC to Syracuse, NY bus

Compare prices and tickets Florence, SC to Syracuse, NY by train

Journey information

Overview: Bus from Florence, SC to Syracuse, NY

FAQs: Bus from Florence, SC to Syracuse, NY

What’s the earliest bus time from Florence, SC to Syracuse, NY?

What’s the latest bus time from Florence, SC to Syracuse, NY?

What is the cheapest month to take a bus from Florence, SC to Syracuse, NY?

Is there a bus from Florence, SC to Syracuse, NY?

Are there toilets on board the bus from Florence, SC to Syracuse, NY?

Are there accessibility options when taking a bus from Florence, SC to Syracuse, NY?

Can I bring my bike on board the bus from Florence, SC to Syracuse, NY?

How can I find the cheapest bus tickets to get from Florence, SC to Syracuse, NY?

Is there food available to purchase on board the bus from Florence, SC to Syracuse, NY?

Is luggage included in the bus ticket price from Florence, SC to Syracuse, NY?

Can I book additional luggage for the bus from Florence, SC to Syracuse, NY?

Can I bring my pet on board the bus from Florence, SC to Syracuse, NY?

Are there USB plugs on board the bus from Florence, SC to Syracuse, NY?

Is there WiFi on board the bus from Florence, SC to Syracuse, NY?