Travel Information
Compare bus and flight for San Antonio, TX to Louisville, KY
Omio recommends booking the bus as it is the most popular option from San Antonio, TX to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $258. For those with little time consider booking a flight which can get you there in 5h 15m. The ticket price range depends on the travel mode: a bus costs an average of $258, and a flight costs an average of $560.
Distance: 950 miles (1529 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$258 Average price Cheapest | $560 Average price |
22h 15m Average total duration 21h 45m Onboard + 30m Additional time* | 8h 15m Average total duration Fastest 5h 15m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Louisville, KY:
A bus is $302 (€244) less than a flight for this route with tickets for a flight from San Antonio, TX to Louisville, KY costing on average $560 (€452).
Other travel options to Louisville, KY take longer:
Bus takes on average 21h 45m.
San Antonio, TX to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 01:30AM | Arrival Time 02:55AM | Duration 25h25 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price $328 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 01:35PM | Duration 26h45 | Departure days Sat | Cheapest price $258 |
Compare prices and tickets San Antonio, TX to Louisville, KY by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 19
May 20
May 21
May 22
May 23
May 24
May 25
Why should you book San Antonio, TX to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from San Antonio, TX to Louisville, KY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from San Antonio, TX to Louisville, KY.
Journey information
Overview: Bus from San Antonio, TX to Louisville, KY
Buses from San Antonio, TX to Louisville, KY run on average 6 times per day, taking around 21h 45m. Cheap bus tickets for this journey start at $258 (€208) if you book in advance.
The earliest bus runs at 01:30, the last at 22:55. The fastest bus covers the 950 miles (1529 km) distance in 26h 45m.
Distance 950 miles (1529 km) |
Average bus duration 21h 45m |
Cheapest ticket price $258 (€208) |
Buses per day 6 |
Fastest bus 26h 45m |
First bus 1:30 AM |
Last bus 10:55 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Bus providers: Greyhound from San Antonio, TX to Louisville, KYYou can travel by bus between San Antonio, TX to Louisville, KY with Greyhound for as low as $258 (€208). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Antonio, TX to Louisville, KY
Find answers to the most common questions about traveling from San Antonio, TX to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Antonio, TX to Louisville, KY
More options for your journey from San Antonio, TX to Louisville, KY
Here are some other resources that might have the information you need


