- Must visit
Muhammad Ali Center
Museum and archive exploring Muhammad Ali's life, boxing career, and humanitarian legacy through immersive exhibits.
Cheapest price on Sep 20
$65
Average ticket price on Sep 20
$70
Fastest journey on Sep 20
8 h 35 m
Average journey duration on Sep 20
8 h 50 m
Buses on Sep 20
7
Distance
562 km
The best way to find a cheap bus ticket from Milwaukee, WI to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to Louisville, KY will cost around $70 if you buy it on the day, but the cheapest tickets can be found for only $65.
It's difficult to get from Milwaukee, WI to Louisville, KY without transferring at least once.
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· Omio recommends booking the bus as it is the most popular option from Milwaukee, WI to Louisville, KY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $76 For those with little time, consider booking a bus, which has an average total journey time of 8h 46m. Average ticket prices depend on the travel mode: a bus costs an average of $76, while a bus costs an average of $76.
Distance: 349 miles (562 km)
Most popular Bus | Driving |
|---|---|
$76 Average price Cheapest | $79 Average price (fuel + tolls) |
8h 46m Average total duration Fastest 8h 16m Onboard + 30m Additional time* | 5h 43m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
This is compared to other travel options from Milwaukee, WI to Louisville, KY:
A bus is $682 less than a flight for this route with tickets for a flight from Milwaukee, WI to Louisville, KY costing on average $757.
Other travel options to Louisville, KY take longer:
Bus takes on average 8h 16m.
Tickets start at around $76 compared to roughly $79 in fuel and tolls — a saving of about $3. The journey takes 8h 16m versus 5h 43m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:25AM | Arrival Time 01:15PM | Duration 8h50 | Departure days Everyday | Cheapest price $48 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:00PM | Duration 10h30 | Departure days Everyday | Cheapest price $53 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 09:55PM | Duration 11h55 | Departure days Wed, Thu | Cheapest price $51 |
Operator Greyhound | Departure Time 09:20AM | Arrival Time 09:55PM | Duration 11h35 | Departure days Wed, Thu | Cheapest price $51 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 09:55PM | Duration 9h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $49 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 09:55PM | Duration 9h00 | Departure days Tue | Cheapest price $51 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 09:55PM | Duration 8h45 | Departure days Mon, Fri, Sat, Sun | Cheapest price $50 |
Operator Greyhound | Departure Time 12:15PM | Arrival Time 09:55PM | Duration 8h40 | Departure days Tue | Cheapest price $51 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 01:15AM | Duration 8h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 01:15AM | Duration 8h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $50 |
Operator Greyhound | Departure Time 03:40PM | Arrival Time 06:55AM | Duration 14h15 | Departure days Thu | Cheapest price $64 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 06:55AM | Duration 9h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $64 |
Operator Greyhound | Departure Time 08:35PM | Arrival Time 06:55AM | Duration 9h20 | Departure days Fri | Cheapest price $60 |
The table below shows live departures for Milwaukee, WI to Louisville, KY buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 3:25 AM Milwaukee, Intermodal Station | 8h50 | 1:15 PM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
· | 6:30 AM Milwaukee, Intermodal Station | 10h30 | 6:00 PM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
FlixBus+ · | 11:50 AM Milwaukee, Intermodal Station | 9h05 | 9:55 PM Louisville, W Broadway (Greyhound Bus Station), KY | 2 transfers | |
FlixBus+ · | 12:10 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 8h45 | 9:55 PM Louisville, W Broadway (Greyhound Bus Station), KY | 2 transfers | |
FlixBus · FlixBus | 3:20 PM Milwaukee, Intermodal Station | 8h55 | 1:15 AM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop), WI | 8h35 | 1:15 AM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
· | 8:30 PM Milwaukee, Intermodal Station | 9h25 | 6:55 AM Louisville, W Broadway (Greyhound Bus Station), KY | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milwaukee, WI to Louisville, KY run on average 7 times per day, taking around 8h 16m. Cheap bus tickets for this journey start at $51 if you book in advance.
The earliest bus runs at 01:50, the last at 21:55. The fastest bus covers the 349 miles (562 km) distance in 6h 45m.
Distance 349 miles (562 km) |
Average bus duration 8h 16m |
Cheapest ticket price $51 |
Buses per day 7 |
Fastest bus 6h 45m |
First bus 1:50 AM |
Last bus 9:55 PM |
Cheapest Month Jun |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Louisville, KY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Louisville, KY trip today.
Museum and archive exploring Muhammad Ali's life, boxing career, and humanitarian legacy through immersive exhibits.
Interactive museum at Churchill Downs covering racing history, Kentucky Derby traditions, and access to select track areas.
Regional art museum in the Speed family mansion area with global collections, modern works, and a sculpture garden.
Revitalized riverfront park with lawns, play areas, public art, and easy access to downtown trails and the Big Four Bridge.
Historic district known for dense Victorian architecture, local shops, and pleasant walking streets near Central Park.
Olmsted-designed urban park with scenic loops, woodlands, picnic areas, and a popular walking route around the reservoir.
Find answers to the most common questions about traveling from Milwaukee, WI to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

Most Milwaukee, WI to Louisville, KY buses use the Milwaukee, Intermodal Station to Louisville, W Broadway (Greyhound Bus Station) station pair. Use this guide to compare Milwaukee, WI and Louisville, KY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milwaukee, Intermodal Station is 1 km from Milwaukee city centre. Public transport options include:
Milwaukee, Intermodal Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafe and vending machines available.
Wi-Fi available in waiting areas. ATMs are aTM machines available inside the station.
Ticket office support is available at Milwaukee, Intermodal Station.
Available at Milwaukee, Intermodal Station: Parking, Taxis, WC.
Accessibility facilities are available at Milwaukee, Intermodal Station: ADA compliant with elevators and ramps.
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) is 10 km from Milwaukee city centre. Public transport options include:
Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food options are available within the airport terminal.
Wi-Fi is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop). ATMs are aTMs are available in the airport terminal.
Ticket office support is available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop).
Available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Milwaukee, General Mitchell International Airport (Wisconsin Coach ORD-MKE Bus Stop): The station is accessible with facilities for disabled passengers.
Louisville, W Broadway (Greyhound Bus Station) is 1 km from Louisville city centre. Public transport options include:
Louisville, W Broadway (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Vending machines and nearby fast food restaurants.
Free WiFi available in the waiting area. ATMs are aTMs available inside the station.
Ticket office support is available at Louisville, W Broadway (Greyhound Bus Station).
Available at Louisville, W Broadway (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Louisville, W Broadway (Greyhound Bus Station): Wheelchair accessible entrances and facilities.
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