4.9
4.6The cheapest and fastest buses from St. Louis, MO to Louisville, KY
Cheapest price
$109
Average price
$109
Fastest journey
8 h 5 m
Average duration
9 h 20 m
Buses per day
2
Distance
389 km
The best way to find a cheap bus ticket from St. Louis, MO to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Louisville, KY will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $109.
Of the 2 buses that leave St. Louis, MO for Louisville, KY on Sun, Nov 23, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 23 the direct buses cover the 389 km distance in an average of 9 h 20 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Sun, Nov 23 the slowest buses will take 10 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Travel Information
Compare bus, flight, and train for St. Louis, MO to Louisville, KY
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from €42. For those with little time consider booking a flight which can get you there in 5h 56m. The ticket price range depends on the travel mode: a bus costs an average of €42, and a flight costs an average of €83.
Distance: 241 miles (389 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
€74 Average price Cheapest | €231 Average price | €110 Average price |
9h 48m Average total duration 9h 18m Onboard + 30m Additional time* | 8h 56m Average total duration Fastest 5h 56m Onboard + 3h 0m Additional time* | 20h 53m Average total duration 20h 23m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
St. Louis, MO to Louisville, KY bus times
The table below shows live departures for St. Louis, MO to Louisville, KY buses for today, Saturday, November 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 7:55 PM St. Louis, MO | 13h40 | 9:35 AM Louisville, KY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Louisville, KY by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 23
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Nov 29
Journey information
Overview: Bus from St. Louis, MO to Louisville, KY
USAUSA
Buses from St. Louis, MO to Louisville, KY run on average 4 times per day, taking around 9h 18m. Cheap bus tickets for this journey start at $51 (€42) if you book in advance.
The earliest bus runs at 00:50, the last at 23:30. The fastest bus covers the 241 miles (389 km) distance in 7h 5m.
Distance 241 miles (389 km) |
Average bus duration 9h 18m |
Cheapest ticket price $51 (€42) |
Buses per day 4 |
Fastest bus 7h 5m |
First bus 00:50 |
Last bus 23:30 |
Bus providers: Greyhound from St. Louis, MO to Louisville, KYYou can travel by bus between St. Louis, MO to Louisville, KY with Greyhound for as low as $51 (€42). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Louisville, KY
Find answers to the most common questions about traveling from St. Louis, MO to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from St. Louis, MO to Louisville, KY, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Louisville, KY
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Louisville, KY
Here are some other resources that might have the information you need
Most popular buses to and from Louisville, KY and St. Louis, MO
Most popular bus connections to Louisville, KY
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