4.9
4.6The cheapest and fastest buses from St. Louis, MO to Louisville, KY
Cheapest price
$59
Average price
$59
Fastest journey
13 h 25 m
Average duration
13 h 25 m
Buses per day
1
Distance
389 km
The best way to find a cheap bus ticket from St. Louis, MO to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Louisville, KY will cost around $59 if you buy it on the day, but the cheapest tickets can be found for only $59.
Of the 1 buses that leave St. Louis, MO for Louisville, KY on Thu, May 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 389 km distance in an average of 13 h 25 m but if you time it right, some buses will get you there in just 13 h 25 m .
On Thu, May 28 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:45 AM13h25St. Louis, MO6:10 PMLouisville, KY$591One-way0 transfers
- 4:45 AM13h25St. Louis, MO6:10 PMLouisville, KY$591One-way0 transfers
Travel Information
Compare bus, train, and flight for St. Louis, MO to Louisville, KY
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 6h 55m. The ticket price range depends on the travel mode: a bus costs an average of $53, and a flight costs an average of $150.
Distance: 241 miles (389 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$65 Average price Cheapest | $163 Average price | $349 Average price | $54 Average price (fuel + tolls) |
9h 43m Average total duration 9h 13m Onboard + 30m Additional time* | 19h 19m Average total duration 18h 49m Onboard + 30m Additional time* | 9h 55m Average total duration Fastest 6h 55m Onboard + 3h 0m Additional time* | 3h 52m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Louisville, KY:
A bus is $98 (€79) less than a train for this route with tickets for a train from St. Louis, MO to Louisville, KY costing on average $163 (€131).
A bus is $283 (€229) less than a flight for this route with tickets for a flight from St. Louis, MO to Louisville, KY costing on average $349 (€281).
Other travel options to Louisville, KY take longer:
Bus takes on average 9h 13m.
Train takes on average 18h 49m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
St. Louis, MO to Louisville, KY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 01:15PM | Duration 10h15 | Departure days Fri | Cheapest price $83 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 05:15PM | Duration 12h45 | Departure days Wed | Cheapest price $64 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 06:10PM | Duration 13h25 | Departure days Thu | Cheapest price $59 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 06:25PM | Duration 12h55 | Departure days Wed | Cheapest price $53 |
Operator Greyhound | Departure Time 07:00AM | Arrival Time 05:15PM | Duration 10h15 | Departure days Tue, Thu | Cheapest price $69 |
Operator Greyhound USA | Departure Time 08:45AM | Arrival Time 06:20PM | Duration 9h35 | Departure days Mon, Fri, Sun | Cheapest price $83 |
Operator Greyhound USA | Departure Time 01:45PM | Arrival Time 01:45PM | Duration 24h00 | Departure days Mon, Sun | Cheapest price $98 |
Operator Greyhound USA | Departure Time 01:55PM | Arrival Time 06:00AM | Duration 16h05 | Departure days Mon, Fri, Sun | Cheapest price $81 |
Operator Amtrak | Departure Time 02:55PM | Arrival Time 06:55AM | Duration 15h00 | Departure days Fri | Cheapest price $173 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 02:00AM | Duration 7h05 | Departure days Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 01:15PM | Duration 12h45 | Departure days Fri | Cheapest price $81 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 02:10PM | Duration 13h25 | Departure days Fri | Cheapest price $82 |
Live departures
St. Louis, MO to Louisville, KY bus times
The table below shows live departures for St. Louis, MO to Louisville, KY buses for tomorrow, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:45 AM St. Louis, MO | 13h25 | 6:10 PM Louisville, KY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Louisville, KY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 27
May 28
May 29
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Jun 01
Jun 02
Why should you book St. Louis, MO to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Louisville, KY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Louisville, KY.
Journey information
Overview: Bus from St. Louis, MO to Louisville, KY
USAUSA
Buses from St. Louis, MO to Louisville, KY run on average 4 times per day, taking around 9h 13m. Cheap bus tickets for this journey start at $53 (€42) if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 241 miles (389 km) distance in 7h 5m.
Distance 241 miles (389 km) |
Average bus duration 9h 13m |
Cheapest ticket price $53 (€42) |
Buses per day 4 |
Fastest bus 7h 5m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 7 days |
Bus providers: Greyhound from St. Louis, MO to Louisville, KYYou can travel by bus between St. Louis, MO to Louisville, KY with Greyhound for as low as $53 (€42). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Louisville, KY
Find answers to the most common questions about traveling from St. Louis, MO to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Louisville, KY
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Louisville, KY
Here are some other resources that might have the information you need
Most popular buses to and from Louisville, KY and St. Louis, MO
Most popular bus connections to Louisville, KY
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