The cheapest and fastest buses from Pittsburgh, PA to Louisville, KY
Cheapest price
$70
Average price
$70
Fastest journey
11 h 10 m
Average duration
11 h 10 m
Buses per day
1
Distance
552 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Louisville, KY will cost around $70 if you buy it on the day, but the cheapest tickets can be found for only $70.
Of the 1 buses that leave Pittsburgh, PA for Louisville, KY on Fri, Mar 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Mar 20 the direct buses cover the 552 km distance in an average of 11 h 10 m but if you time it right, some buses will get you there in just 11 h 10 m .
On Fri, Mar 20 the slowest buses will take 11 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Pittsburgh, PA to Louisville, KY
Omio recommends booking the bus as it is the most popular option from Pittsburgh, PA to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $64. For those with little time consider booking a flight which can get you there in 6h 4m. The ticket price range depends on the travel mode: a bus costs an average of $64, and a flight costs an average of $172.
Distance: 342 miles (552 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$73 Average price Cheapest | $202 Average price | $312 Average price |
10h 8m Average total duration 9h 38m Onboard + 30m Additional time* | 25h 23m Average total duration 24h 53m Onboard + 30m Additional time* | 9h 4m Average total duration Fastest 6h 4m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Pittsburgh, PA to Louisville, KY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Why should you book Pittsburgh, PA to Louisville, KY buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Louisville, KY.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Pittsburgh, PA to Louisville, KY.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Louisville, KY.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Pittsburgh, PA to Louisville, KY.
Journey information
Overview: Bus from Pittsburgh, PA to Louisville, KY
Buses from Pittsburgh, PA to Louisville, KY run on average 4 times per day, taking around 9h 38m. Cheap bus tickets for this journey start at $64 (€52) if you book in advance.
The earliest bus runs at 01:35, the last at 20:00. The fastest bus covers the 342 miles (552 km) distance in 10h 45m.
Distance 342 miles (552 km) |
Average bus duration 9h 38m |
Cheapest ticket price $64 (€52) |
Buses per day 4 |
Fastest bus 10h 45m |
First bus 01:35 |
Last bus 20:00 |
Cheapest month Sep |
Cheapest day Wed |
High season Apr - Jun |
Low season Oct - Dec |
Bus providers: Greyhound, FlixBus from Pittsburgh, PA to Louisville, KYYou can travel by bus between Pittsburgh, PA to Louisville, KY with Greyhound, FlixBus for as low as $64 (€52). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Pittsburgh, PA to Louisville, KY
Find answers to the most common questions about traveling from Pittsburgh, PA to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Pittsburgh, PA to Louisville, KY
Most popular bus connections from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Louisville, KY
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