Florence, SC to Louisville, KY train

Tue, Dec 16
+ Add return
Regionale
Deutsche Bahn
iryo
Italo
AVE
1,000+ travel companies
Regionale
Deutsche Bahn
iryo
Italo
AVE
1,000+ travel companies
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Compare prices and tickets Florence, SC to Louisville, KY by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Dec 16
Wed
Dec 17
Thu
Dec 18
Fri
Dec 19
Sat
Dec 20
Sun
Dec 21
Mon
Dec 22

Journey information

Overview: Train from Florence, SC to Louisville, KY

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Take a train from Florence, SC to Louisville, KY and enjoy the approximately 436 miles (702 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest train runs at 08:00, the last at 08:10.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $160 (€128)
Distance
436 miles (702 km)
First train
08:00
Last train
08:10
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $160 (€128)

FAQs: Trains from Florence, SC to Louisville, KY

Find answers to the most common questions about traveling from Florence, SC to Louisville, KY by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

FAQs
For a well-rounded experience in Louisville, KY, plan to spend about 2 to 3 days to explore key attractions like the Kentucky Derby Museum, Louisville Slugger Museum, and the vibrant NuLu district.
The last train from Florence, SC to Louisville, KY leaves at 8:10 AM.
The train journey from Florence, SC to Louisville, KY offers a scenic experience through diverse landscapes, including views of the Appalachian foothills, charming small towns, and lush greenery, providing a pleasant and picturesque travel experience.
The distance by train from Florence, SC to Louisville, KY is 436 miles (702 km).
The cheapest way to get from Florence, SC to Louisville, KY is by bus, with a cost of around $160 (€128).
Unfortunately, there is no night train available from Florence, SC to Louisville, KY.
The first train from Florence, SC to Louisville, KY leaves at 8:00 AM.
No, you cannot take the train from Florence, SC to Louisville, KY.

More options for your journey from Florence, SC to Louisville, KY

Here are some other resources that might have the information you need

Buses from Florence, SC to Louisville, KY
Tickets and more information for trains to Florence, SC
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