Jacksonville, FL to Florence, SC bus with FlixBus

Wed, Aug 05
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FlixBus
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Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from Jacksonville, FL to Florence, SC

Showing times and prices for Aug 05

Cheapest price

€50

Average price

€50

Fastest journey

5 h 10 m

Average duration

5 h 10 m

Buses per day

1

Distance

465 km

Cheap tickets

The best way to find a cheap bus ticket from Jacksonville, FL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Jacksonville, FL to Florence, SC will cost around €50 if you buy it on the day, but the cheapest tickets can be found for only €50.

Fast buses

Of the 1 buses that leave Jacksonville, FL for Florence, SC on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Aug 05 the direct buses cover the 465 km distance in an average of 5 h 10 m but if you time it right, some buses will get you there in just 5 h 10 m .

On Wed, Aug 05 the slowest buses will take 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Flixbus USA
    8:15 AM5h10
    Jacksonville, FL
    1:25 PMFlorence, SC
    €501One-way
    0 transfers

Journey information

Overview: Bus from Jacksonville, FL to Florence, SC

USAUSA
USAUSA
Icon of bus

Buses from Jacksonville, FL to Florence, SC run on average 2 times per day, taking around 5h 30m. Cheap bus tickets for this journey start at €51 if you book in advance.

There are 2 buses per day. The earliest bus runs at 05:30, the last at 18:30. The fastest bus covers the 288 miles (465 km) distance in 5h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
288 miles (465 km)
Average bus duration
5h 30m
Cheapest ticket price
€51
Buses per day
2
Direct buses
2
Fastest bus
5h 10m
First bus
5:30 AM
Last bus
6:30 PM
Cheapest Month
Sep
Cheapest Day
Tue
High Season
Jan - Mar
Low Season
Jul - Sep
Busiest Day
Sat
Least Busy Day
Sat
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Jacksonville, FL to Florence, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Flixbus USA
Departure Time
08:15AM
Arrival Time
01:25PM
Duration
5h10
Departure days
Tue, Wed, Sun
Cheapest price
€50
Operator
FlixBus
Departure Time
06:30PM
Arrival Time
12:05AM
Duration
5h35
Departure days
Fri
Cheapest price
€48
Operator
FlixBus
Departure Time
10:30PM
Arrival Time
04:05AM
Duration
5h35
Departure days
Mon, Thu
Cheapest price
€51
Operator
FlixBus
Departure Time
11:30PM
Arrival Time
05:05AM
Duration
5h35
Departure days
Sat
Cheapest price
€55

Live departures

Jacksonville, FL to Florence, SC bus times

The table below shows live departures for Jacksonville, FL to Florence, SC buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Flixbus USA8:15 AM Jacksonville, FL
5h10
1:25 PM Florence, SC0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Why should you book Jacksonville, FL to Florence, SC buses with Omio?

FlixBus operates all buses services from Jacksonville, FL to Florence, SC.
Omio is an official ticket reseller for all your travel options from Jacksonville, FL to Florence, SC.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Jacksonville, FL to Florence, SC.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Jacksonville, FL to Florence, SC.

Bus providers: FlixBus from Jacksonville, FL to Florence, SCYou can travel by bus between Jacksonville, FL to Florence, SC with FlixBus for as low as €51. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
5h 10m
Cheapest Price
€51
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Jacksonville, FL to Florence, SC

Find answers to the most common questions about traveling from Jacksonville, FL to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Jacksonville, FL to Florence, SC can start from as little as €51 when you book in advance. The average bus ticket price for Jacksonville, FL to Florence, SC is €57 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Jacksonville, FL to Florence, SC is 5h 10m to travel the 288 miles (465 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Jacksonville, FL to Florence, SC leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Jacksonville, FL to Florence, SC leaves at 6:30 PM.
Yes, there are 2 direct buses a day from Jacksonville, FL to Florence, SC with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Jacksonville, FL to Florence, SC, you can count on FlixBus for the best way to get you to Florence, SC. You can also check all possible bus companies who offer a service between Jacksonville, FL and Florence, SC and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 2 ways to travel between Jacksonville, FL and Florence, SC including taking a bus and train.
Yes, the following accessibility options are available when taking the bus from Jacksonville, FL to Florence, SC:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Jacksonville, FL to Florence, SC for bus company FlixBus.
Whether you can cancel your bus ticket from Jacksonville, FL to Florence, SC depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Jacksonville, FL to Florence, SC.
Yes, the following luggage options are included when booking a bus ticket from Jacksonville, FL to Florence, SC:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Jacksonville, FL to Florence, SC:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Jacksonville, FL to Florence, SC. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Jacksonville, FL to Florence, SC with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Jacksonville, FL to Florence, SC with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Jacksonville, FL to Florence, SC with the following bus company: FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Jacksonville, FL to Florence, SC

Most Jacksonville, FL to Florence, SC buses use the Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St to Florence, S Irby St (Greyhound Bus Stop) station pair. Use this guide to compare Jacksonville, FL and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Jacksonville
Arrival bus stations in Florence
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St
City-centre transport

Getting to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St from Jacksonville city centre

Bus1, 11, 18, 205, 3, Nassau, St. Johns, Clay · 12m · €3 · every ~18 min
1, 19, 3 · 17m · €3 · every ~17 min
SubwaySky · 10m · every ~4 min

More options for your journey from Jacksonville, FL to Florence, SC

Here are some other resources that might have the information you need

Return journeys for buses from Florence, SC to Jacksonville, FL
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Tickets and more information for coaches to Florence, SC

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