Syracuse, NY to Florence, SC bus

Sat, May 02
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Travel Information

Compare bus for Syracuse, NY to Florence, SC

Omio recommends booking the train as it is the most popular option from Syracuse, NY to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $220. For those with little time consider booking a bus which can get you there in 20h 45m. The ticket price range depends on the travel mode: a bus costs an average of $220, and a train costs an average of $316.

Distance: 641 miles (1033 km)

Compare bus with

Bus
Most popular
Train

$220

Average price

Cheapest

$374

Average price

21h 15m

Average total duration

Fastest

20h 45m

Onboard

+

30m

Additional time*

25h 26m

Average total duration

24h 56m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Syracuse, NY to Florence, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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May 02
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Journey information

Overview: Bus from Syracuse, NY to Florence, SC

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Buses from Syracuse, NY to Florence, SC run on average 2 times per day, taking around 20h 45m. Cheap bus tickets for this journey start at $220 (€176) if you book in advance.

The earliest bus runs at 00:05, the last at 21:00. The fastest bus covers the 641 miles (1033 km) distance in 20h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
641 miles (1033 km)
Average bus duration
20h 45m
Cheapest ticket price
$220 (€176)
Buses per day
2
Fastest bus
20h 45m
First bus
12:05 AM
Last bus
9:00 PM
Cheapest Month
Sep
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Jan - Mar
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Syracuse, NY to Florence, SC

Find answers to the most common questions about traveling from Syracuse, NY to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Syracuse, NY to Florence, SC can start from as little as $220 (€176) when you book in advance. The average bus ticket price for Syracuse, NY to Florence, SC is $220 (€176) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Syracuse, NY to Florence, SC is 20h 45m to travel the 641 miles (1033 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Syracuse, NY to Florence, SC leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Syracuse, NY to Florence, SC leaves at 9:00 PM.
A trip to Florence, SC from Syracuse, NY is worth doing but not as a day trip with a journey time of 20h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Syracuse, NY to Florence, SC is September.
Yes, you can take a between Syracuse, NY and Florence, SC.
No, the bus from Syracuse, NY to Florence, SC has no accessibility options.
No, there are no bathrooms on board the bus from Syracuse, NY to Florence, SC.
No, bikes are not allowed on board the bus from Syracuse, NY to Florence, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Syracuse, NY to Florence, SC.
No, luggage for the bus from Syracuse, NY to Florence, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Syracuse, NY to Florence, SC.
Unfortunately, pets are not allowed on the bus from Syracuse, NY to Florence, SC.
No, there are no USB plugs on board the bus from Syracuse, NY to Florence, SC.
No, there is no WiFi on board the bus from Syracuse, NY to Florence, SC.
Since neither Syracuse, NY nor Florence, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Syracuse, NY to Florence, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Syracuse, NY to Florence, SC

Syracuse
Florence
The major bus station for departures in Syracuse is Syracuse, Walsh Cir (Syracuse Bus Station). Find all the information you need to know about services, amenities and connections at Syracuse, Walsh Cir (Syracuse Bus Station) for your trip from Syracuse to Florence.
Syracuse, Walsh Cir (Syracuse Bus Station)
information

More options for your journey from Syracuse, NY to Florence, SC

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Return journeys for buses from Florence, SC to Syracuse, NY
Tickets and more information for coaches to Syracuse, NY
Tickets and more information for coaches to Florence, SC

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