4.9
4.6The cheapest and fastest buses from Syracuse, NY to Florence, SC
Cheapest price on Sep 17
$99
Average ticket price on Sep 17
$109
Fastest journey on Sep 17
20 h 20 m
Average journey duration on Sep 17
1 d 2 h 33 m
Buses on Sep 17
2
Distance
1033 km
The best way to find a cheap bus ticket from Syracuse, NY to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Florence, SC will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $99.
It's difficult to get from Syracuse, NY to Florence, SC without transferring at least 2 times.
FlixBus+
· 9:25 AM20h20Syracuse, Walsh Cir (Syracuse Bus Station), NY5:45 AMFlorence, W Lucas St (TA Gas Station), SC$991One-way2 transfers- · · +FlixBus9:00 PM32h45Syracuse, Walsh Cir (Syracuse Bus Station), NY5:45 AMFlorence, W Lucas St (TA Gas Station), SC$1191One-way3 transfers
- FlixBus+ · 9:25 AM20h20Syracuse, Walsh Cir (Syracuse Bus Station), NY5:45 AMFlorence, W Lucas St (TA Gas Station), SC$991One-way2 transfers
- · · +FlixBus9:00 PM32h45Syracuse, Walsh Cir (Syracuse Bus Station), NY5:45 AMFlorence, W Lucas St (TA Gas Station), SC$1191One-way3 transfers
Travel Information
Compare bus and train for Syracuse, NY to Florence, SC
Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Florence, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $156 For those with little time, consider booking a bus, which has an average total journey time of 18h 42m. Average ticket prices depend on the travel mode: a bus costs an average of $156, while a train costs an average of $770.
Distance: 641 miles (1033 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$156 Average price Cheapest | $770 Average price | $157 Average price (fuel + tolls) |
18h 42m Average total duration Fastest 18h 12m Onboard + 30m Additional time* | 18h 53m Average total duration 18h 23m Onboard + 30m Additional time* | 11h 39m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Syracuse, NY to Florence, SC:
A bus is $614 less than a train for this route with tickets for a train from Syracuse, NY to Florence, SC costing on average $770.
Other travel options to Florence, SC take longer:
Train takes on average 18h 23m.
Tickets start at around $156 compared to roughly $157 in fuel and tolls — a saving of about $0.69. The journey takes 18h 12m versus 11h 39m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Syracuse, NY to Florence, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:25AM | Arrival Time 05:45AM | Duration 20h20 | Departure days Thu | Cheapest price $99 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 05:45AM | Duration 32h45 | Departure days Thu | Cheapest price $119 |
Journey information
Overview: Bus from Syracuse, NY to Florence, SC
USAUSA
Buses from Syracuse, NY to Florence, SC run on average 3 times per day, taking around 18h 12m. Cheap bus tickets for this journey start at $115 if you book in advance.
The earliest bus runs at 00:05, the last at 21:00. The fastest bus covers the 641 miles (1033 km) distance in 16h 35m.
Distance 641 miles (1033 km) |
Average bus duration 18h 12m |
Cheapest ticket price $115 |
Buses per day 3 |
Fastest bus 16h 35m |
First bus 12:05 AM |
Last bus 9:00 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 14 days |
FAQs: Bus from Syracuse, NY to Florence, SC
Find answers to the most common questions about traveling from Syracuse, NY to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Syracuse, NY to Florence, SC
Most Syracuse, NY to Florence, SC buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to Florence, W Lucas St (TA Gas Station) station pair, with some services arriving at Florence, S Irby St (Greyhound Bus Stop). Use this guide to compare Syracuse, NY and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Syracuse, NY station do buses to Florence, SC leave from?
Getting to Syracuse, Walsh Cir (Syracuse Bus Station) from Syracuse city centre
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) bus station facilities and services
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Tickets and information
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Parking, taxis and toilets
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Which Florence, SC station do buses from Syracuse, NY arrive at?
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
More options for your journey from Syracuse, NY to Florence, SC
Here are some other resources that might have the information you need
Most popular buses to and from Florence, SC and Syracuse, NY
Most popular bus connections to Florence, SC
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