Wilmington, DE to Florence, SC bus

Sun, Mar 22
+ Add return
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Wilmington, DE to Florence, SC

Showing times and prices for Mar 22

Cheapest price

$113

Average price

$113

Fastest journey

14 h 20 m

Average duration

14 h 20 m

Buses per day

1

Distance

722 km

Cheap tickets

The best way to find a cheap bus ticket from Wilmington, DE to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Wilmington, DE to Florence, SC will cost around $113 if you buy it on the day, but the cheapest tickets can be found for only $113.

Fast buses

It's difficult to get from Wilmington, DE to Florence, SC without transferring at least 2 times.

Greyhound USA
09:25PM14h20
Wilmington, DE
11:45AMFlorence, SC
$1131One-way
2 transfers

Compare prices and tickets Wilmington, DE to Florence, SC by train

Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Mar 22
Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28

Journey information

Overview: Bus from Wilmington, DE to Florence, SC

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Take a bus from Wilmington, DE to Florence, SC and enjoy the approximately 448 miles (722 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:05, the last at 21:25.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $179 (€145)
Distance
448 miles (722 km)
Buses per day
2
First bus
00:05
Last bus
21:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $179 (€145)

FAQs: Bus from Wilmington, DE to Florence, SC

Find answers to the most common questions about traveling from Wilmington, DE to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Wilmington, DE to Florence, SC leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Wilmington, DE to Florence, SC leaves at 9:25 PM.
The cheapest month for a bus from Wilmington, DE to Florence, SC is October.
Yes, you can take a train between Wilmington, DE and Florence, SC.
No, there are no bathrooms on board the bus from Wilmington, DE to Florence, SC.
No, the bus from Wilmington, DE to Florence, SC has no accessibility options.
No, bikes are not allowed on board the bus from Wilmington, DE to Florence, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Wilmington, DE to Florence, SC.
No, luggage for the bus from Wilmington, DE to Florence, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Wilmington, DE to Florence, SC.
Unfortunately, pets are not allowed on the bus from Wilmington, DE to Florence, SC.
No, there are no USB plugs on board the bus from Wilmington, DE to Florence, SC.
No, there is no WiFi on board the bus from Wilmington, DE to Florence, SC.

popular bus stations

Popular bus stations from Wilmington, DE to Florence, SC

Wilmington
Florence
The major bus station for departures in Wilmington is Wilmington, Amtrak Station @ ML King-French. Find all the information you need to know about services, amenities and connections at Wilmington, Amtrak Station @ ML King-French for your trip from Wilmington to Florence.
Wilmington, Amtrak Station @ ML King-French
information

More options for your journey from Wilmington, DE to Florence, SC

Here are some other resources that might have the information you need

Return journeys for buses from Florence, SC to Wilmington, DE
Tickets and more information for coaches to Wilmington, DE
Tickets and more information for coaches to Florence, SC

Most popular buses to and from Florence, SC and Wilmington, DE

Bus Wilmington, DE - Boston, MA
Bus Wilmington, DE - New York, NY
Bus Wilmington, DE - Los Angeles, CA
Bus Wilmington, DE - Chicago, IL
Bus Wilmington, DE - Washington, DC
Bus Wilmington, DE - Philadelphia, PA
Bus Wilmington, DE - Dallas, TX
Bus Wilmington, DE - Orlando, FL
Bus Wilmington, DE - Atlanta, GA
Bus Wilmington, DE - Miami, FL
Bus Wilmington, DE - Tampa, FL
Bus Wilmington, DE - Baltimore, MD
Bus Wilmington, DE - Newark, NJ
Bus Wilmington, DE - Denver, CO
Bus Wilmington, DE - Charlotte, NC
Bus Wilmington, DE - Nashville, TN
Bus Wilmington, DE - Raleigh, NC
Bus Wilmington, DE - Pittsburgh, PA
Bus Wilmington, DE - Jacksonville, FL
Bus Wilmington, DE - Richmond, VA
Bus Wilmington, DE - Cleveland, OH
Bus Wilmington, DE - Fort Lauderdale, FL
Bus Boston, MA - Florence, SC
Bus New York, NY - Florence, SC
Bus Washington, DC - Florence, SC
Bus Philadelphia, PA - Florence, SC
Bus Orlando, FL - Florence, SC
Bus Miami, FL - Florence, SC
Bus Tampa, FL - Florence, SC
Bus Baltimore, MD - Florence, SC
Bus Newark, NJ - Florence, SC
Bus Milwaukee, WI - Florence, SC
Bus Charlotte, NC - Florence, SC
Bus Raleigh, NC - Florence, SC
Bus Pittsburgh, PA - Florence, SC
Bus Jacksonville, FL - Florence, SC
Bus Richmond, VA - Florence, SC
Bus Cleveland, OH - Florence, SC
Bus Fort Lauderdale, FL - Florence, SC
Bus Syracuse, NY - Florence, SC
Bus West Palm Beach, FL - Florence, SC
Bus Colorado Springs, CO - Florence, SC
Bus Savannah, GA - Florence, SC
Bus Fayetteville, NC - Florence, SC
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