4.9
4.6The cheapest and fastest buses from Pittsburgh, PA to Florence, SC
Cheapest price on Sep 19
$164
Average ticket price on Sep 19
$170
Fastest journey on Sep 19
15 h 15 m
Average journey duration on Sep 19
1 d 5 h 23 m
Buses on Sep 19
2
Distance
695 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Florence, SC will cost around $170 if you buy it on the day, but the cheapest tickets can be found for only $164.
It's difficult to get from Pittsburgh, PA to Florence, SC without transferring at least 2 times.
8:00 PM43h30Pittsburgh, PA3:30 PMFlorence, SC$1641One-way3 transfers- 8:30 PM15h15Pittsburgh, PA11:45 AMFlorence, SC$1761One-way2 transfers
- 8:30 PM15h15Pittsburgh, PA11:45 AMFlorence, SC$1761One-way2 transfers
- 8:00 PM43h30Pittsburgh, PA3:30 PMFlorence, SC$1641One-way3 transfers
Travel Information
Compare train and bus for Pittsburgh, PA to Florence, SC
Omio recommends booking the train as it is the most popular option from Pittsburgh, PA to Florence, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $161 For those with little time, consider booking a train, which has an average total journey time of 17h 28m. Average ticket prices depend on the travel mode: a bus costs an average of $161, while a train costs an average of $295.
Distance: 431 miles (695 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$161 Average price Cheapest | $295 Average price | $112 Average price (fuel + tolls) |
18h 44m Average total duration 18h 14m Onboard + 30m Additional time* | 17h 28m Average total duration Fastest 16h 58m Onboard + 30m Additional time* | 8h 49m Average total duration (door-to-door) |
 Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pittsburgh, PA to Florence, SC:
A bus is $134 less than a train for this route with tickets for a train from Pittsburgh, PA to Florence, SC costing on average $295.
Other travel options to Florence, SC take longer:
Bus takes on average 18h 14m.
Tickets start at around $161 compared to roughly $112 in fuel and tolls — a saving of about $-49.84. The journey takes 18h 14m versus 8h 49m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Pittsburgh, PA to Florence, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 03:45PM | Duration 15h15 | Departure days Thu | Cheapest price $345 |
Operator FlixBus | Departure Time 11:45AM | Arrival Time 05:45AM | Duration 18h00 | Departure days Fri | Cheapest price $108 |
Operator Greyhound USA | Departure Time 08:00PM | Arrival Time 03:30PM | Duration 43h30 | Departure days Tue, Thu, Sat | Cheapest price $164 |
Operator Greyhound USA | Departure Time 08:30PM | Arrival Time 11:45AM | Duration 15h15 | Departure days Tue, Thu, Sat, Sun | Cheapest price $176 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 05:45AM | Duration 32h00 | Departure days Fri | Cheapest price $96 |
Live departures
Pittsburgh, PA to Florence, SC bus times
The table below shows live departures for Pittsburgh, PA to Florence, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 11:45 AM Pittsburgh, Greyhound Bus Station, PA | 18h00 | 5:45 AM Florence, W Lucas St (TA Gas Station), SC | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 9:45 PM Pittsburgh, Greyhound Bus Station, PA | 32h00 | 5:45 AM Florence, W Lucas St (TA Gas Station), SC | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pittsburgh, PA to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Sep 24
Sep 25
Why should you book Pittsburgh, PA to Florence, SC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Florence, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Pittsburgh, PA to Florence, SC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Florence, SC.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Pittsburgh, PA to Florence, SC.
Journey information
Overview: Bus from Pittsburgh, PA to Florence, SC
USAUSA
Buses from Pittsburgh, PA to Florence, SC run on average 2 times per day, taking around 18h 14m. Cheap bus tickets for this journey start at $99 if you book in advance.
The earliest bus runs at 00:05, the last at 20:35. The fastest bus covers the 431 miles (695 km) distance in 13h 0m.
Distance 431 miles (695 km) |
Average bus duration 18h 14m |
Cheapest ticket price $99 |
Buses per day 2 |
Fastest bus 13h 0m |
First bus 12:05 AM |
Last bus 8:35 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Bus providers: FlixBus, Greyhound from Pittsburgh, PA to Florence, SCYou can travel by bus between Pittsburgh, PA to Florence, SC with FlixBus, Greyhound for as low as $99. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Pittsburgh, PA to Florence, SC
Find answers to the most common questions about traveling from Pittsburgh, PA to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Pittsburgh, PA to Florence, SC
Most Pittsburgh, PA to Florence, SC buses use the Pittsburgh, Greyhound Bus Station to Florence, W Lucas St (TA Gas Station) station pair, with some services arriving at Florence, S Irby St (Greyhound Bus Stop). Use this guide to compare Pittsburgh, PA and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Pittsburgh, PA station do buses to Florence, SC leave from?
Getting to Pittsburgh, Greyhound Bus Station from Pittsburgh city centre
Pittsburgh, Greyhound Bus Station bus station facilities and services
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack bar available on site
Wi-Fi and ATMs
Available throughout the station. ATMs are aTM located near the entrance.
Tickets and information
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Parking, taxis and toilets
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.
Which Florence, SC station do buses from Pittsburgh, PA arrive at?
Getting to Florence, W Lucas St (TA Gas Station) from Florence city centre
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) bus station facilities and services
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food and snacks available at the gas station.
Wi-Fi and ATMs
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Tickets and information
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Parking, taxis and toilets
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Getting to Florence, S Irby St (Greyhound Bus Stop) from Florence city centre
Florence, S Irby St (Greyhound Bus Stop) bus station facilities and services
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Tickets and information
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Parking, taxis and toilets
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Most popular bus connections from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Florence, SC
Here are some other resources that might have the information you need
Most popular buses to and from Florence, SC and Pittsburgh, PA
Most popular bus connections to Florence, SC
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