4.9
4.6The cheapest and fastest buses from St. Louis, MO to Santa Ana, CA
Cheapest price
$506
Average price
$513
Fastest journey
1 d 18 h 10 m
Average duration
1 d 20 h 45 m
Buses per day
2
Distance
2532 km
The best way to find a cheap bus ticket from St. Louis, MO to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Santa Ana, CA will cost around $513 if you buy it on the day, but the cheapest tickets can be found for only $506.
It's difficult to get from St. Louis, MO to Santa Ana, CA without transferring at least once.
1:20 AM42h10St. Louis, MO7:30 PMSanta Ana, CA$5061One-way1 transfer- 8:40 AM47h20St. Louis, MO8:00 AMSanta Ana, CA$5211One-way1 transfer
- 1:20 AM42h10St. Louis, MO7:30 PMSanta Ana, CA$5061One-way1 transfer
- 8:40 AM47h20St. Louis, MO8:00 AMSanta Ana, CA$5211One-way1 transfer
Journey information
Overview: Bus from St. Louis, MO to Santa Ana, CA
USAUSA
Buses from St. Louis, MO to Santa Ana, CA run on average 3 times per day, taking around 46h 45m. Cheap bus tickets for this journey start at $338 (€275) but you can travel from only $275 (€224) by train.
The earliest bus runs at 01:20, the last at 21:20. The fastest bus covers the 1573 miles (2532 km) distance in 44h 10m.
Distance 1573 miles (2532 km) |
Average bus duration 46h 45m |
Cheapest ticket price $338 (€275) |
Buses per day 3 |
Fastest bus 44h 10m |
First bus 1:20 AM |
Last bus 9:20 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
St. Louis, MO to Santa Ana, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 01:20AM | Arrival Time 07:30PM | Duration 42h10 | Departure days Mon, Wed, Thu | Cheapest price $506 |
Operator Greyhound | Departure Time 07:20AM | Arrival Time 03:30AM | Duration 44h10 | Departure days Tue | Cheapest price $338 |
Operator Greyhound USA | Departure Time 08:40AM | Arrival Time 08:00AM | Duration 47h20 | Departure days Mon, Wed, Thu, Sun | Cheapest price $521 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 03:00PM | Duration 49h20 | Departure days Fri | Cheapest price $370 |
Live departures
St. Louis, MO to Santa Ana, CA bus times
The table below shows live departures for St. Louis, MO to Santa Ana, CA buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:20 AM St. Louis, MO | 42h10 | 7:30 PM Santa Ana, CA | 1 transfer | |
| 8:40 AM St. Louis, MO | 47h20 | 8:00 AM Santa Ana, CA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book St. Louis, MO to Santa Ana, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Santa Ana, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Santa Ana, CA.
Bus providers: Greyhound from St. Louis, MO to Santa Ana, CAYou can travel by bus between St. Louis, MO to Santa Ana, CA with Greyhound for as low as $275 (€224). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Santa Ana, CA
Find answers to the most common questions about traveling from St. Louis, MO to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Santa Ana, CA
Most St. Louis, MO to Santa Ana, CA buses use the St. Louis, S 15th St (Civic center) to Santa Ana, E Santa Ana Blvd (Train Station) station pair. Use this guide to compare St. Louis, MO and Santa Ana, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which St. Louis, MO station do buses to Santa Ana, CA leave from?
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Getting to St. Louis, Lambert International Airport from St. Louis city centre
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
St. Louis, Lambert International Airport bus station facilities and services
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options available in terminals.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Tickets and information
Ticket office support is available at St. Louis, Lambert International Airport.
Parking, taxis and toilets
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Which Santa Ana, CA station do buses from St. Louis, MO arrive at?
Getting to Santa Ana, E Santa Ana Blvd (Train Station) from Santa Ana city centre
Santa Ana, E Santa Ana Blvd (Train Station) is 1 km from Santa Ana city centre. Public transport options include:
Santa Ana, E Santa Ana Blvd (Train Station) bus station facilities and services
Santa Ana, E Santa Ana Blvd (Train Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Santa Ana, E Santa Ana Blvd (Train Station). ATMs are available at Santa Ana, E Santa Ana Blvd (Train Station).
Tickets and information
Ticket office support is available at Santa Ana, E Santa Ana Blvd (Train Station).
Parking, taxis and toilets
Available at Santa Ana, E Santa Ana Blvd (Train Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Santa Ana, E Santa Ana Blvd (Train Station): Bus access is available.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Santa Ana, CA
Here are some other resources that might have the information you need
Most popular buses to and from Santa Ana, CA and St. Louis, MO
Most popular bus connections to Santa Ana, CA
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