4.9
4.6The cheapest and fastest buses from St. Louis, MO to Santa Ana, CA
Cheapest price
$508
Average price
$516
Fastest journey
1 d 18 h 10 m
Average duration
1 d 20 h 45 m
Buses per day
2
Distance
2532 km
The best way to find a cheap bus ticket from St. Louis, MO to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Santa Ana, CA will cost around $516 if you buy it on the day, but the cheapest tickets can be found for only $508.
It's difficult to get from St. Louis, MO to Santa Ana, CA without transferring at least once.
Travel Information
Compare train, bus, and flight for St. Louis, MO to Santa Ana, CA
Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Santa Ana, CA among Omio's users. If you are prioritising price take the train with prices starting from $276. For those with little time consider booking a flight which can get you there in 12h 33m. The ticket price range depends on the travel mode: a train costs an average of $276, and a flight costs an average of $532.
Distance: 1573 miles (2532 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$340 Average price | $532 Average price | $276 Average price Cheapest |
44h 40m Average total duration 44h 10m Onboard + 30m Additional time* | 15h 33m Average total duration Fastest 12h 33m Onboard + 3h 0m Additional time* | 62h 20m Average total duration 61h 50m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
St. Louis, MO to Santa Ana, CA bus times
The table below shows live departures for St. Louis, MO to Santa Ana, CA buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:40 AM St. Louis, MO | 47h20 | 8:00 AM Santa Ana, CA | 1 transfer | |
| Monday, March 23 | |||||
| 1:20 AM St. Louis, MO | 42h10 | 7:30 PM Santa Ana, CA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Santa Ana, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
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Mar 29
Why should you book St. Louis, MO to Santa Ana, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Santa Ana, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Santa Ana, CA.
Journey information
Overview: Bus from St. Louis, MO to Santa Ana, CA
USAUSA
Buses from St. Louis, MO to Santa Ana, CA run on average 3 times per day, taking around 44h 10m. Cheap bus tickets for this journey start at $340 (€275) but you can travel from only $276 (€224) by train.
The earliest bus runs at 01:20, the last at 21:20. The fastest bus covers the 1573 miles (2532 km) distance in 44h 10m.
Distance 1573 miles (2532 km) |
Average bus duration 44h 10m |
Cheapest ticket price $340 (€275) |
Buses per day 3 |
Fastest bus 44h 10m |
First bus 01:20 |
Last bus 21:20 |
Bus providers: Greyhound from St. Louis, MO to Santa Ana, CAYou can travel by bus between St. Louis, MO to Santa Ana, CA with Greyhound for as low as $276 (€224). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from St. Louis, MO to Santa Ana, CA
Find answers to the most common questions about traveling from St. Louis, MO to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from St. Louis, MO to Santa Ana, CA
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Santa Ana, CA
Here are some other resources that might have the information you need
Most popular buses to and from Santa Ana, CA and St. Louis, MO
Most popular bus connections to Santa Ana, CA
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