The cheapest and fastest buses from San Diego, CA to Santa Ana, CA
Cheapest price
$22
Average price
$22
Fastest journey
1 h 55 m
Average duration
2 h 15 m
Buses per day
2
Distance
132 km
The best way to find a cheap bus ticket from San Diego, CA to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to Santa Ana, CA will cost around $22 if you buy it on the day, but the cheapest tickets can be found for only $22.
Of the 2 buses that leave San Diego, CA for Santa Ana, CA on Mon, Jan 12, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jan 12 the direct buses cover the 132 km distance in an average of 2 h 15 m but if you time it right, some buses will get you there in just 1 h 55 m .
On Mon, Jan 12 the slowest buses will take 2 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train and bus for San Diego, CA to Santa Ana, CA
Omio recommends booking the train as it is the most popular option from San Diego, CA to Santa Ana, CA among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a train which can get you there in 1h 55m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of €13, and a train costs an average of €26.
Distance: 82 miles (132 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€19 Average price Cheapest | €26 Average price |
2h 42m Average total duration 2h 12m Onboard + 30m Additional time* | 2h 25m Average total duration Fastest 1h 55m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
San Diego, CA to Santa Ana, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 05:30AM | Arrival Time 07:59AM | Duration 2h29 | Departure days Sun | Cheapest price $33 |
Operator Greyhound | Departure Time 06:00AM | Arrival Time 08:40AM | Duration 2h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator Greyhound | Departure Time 06:45AM | Arrival Time 08:40AM | Duration 1h55 | Departure days Thu, Fri, Sat, Sun | Cheapest price $25 |
Operator Amtrak | Departure Time 07:30AM | Arrival Time 09:59AM | Duration 2h29 | Departure days Sun | Cheapest price $33 |
Operator Amtrak | Departure Time 09:30AM | Arrival Time 11:59AM | Duration 2h29 | Departure days Sun | Cheapest price $33 |
Operator Amtrak | Departure Time 11:45AM | Arrival Time 02:59PM | Duration 3h14 | Departure days Sun | Cheapest price $33 |
Operator Amtrak | Departure Time 12:45PM | Arrival Time 04:02PM | Duration 3h17 | Departure days Sun | Cheapest price $33 |
Operator Amtrak | Departure Time 03:00PM | Arrival Time 06:02PM | Duration 3h02 | Departure days Sun | Cheapest price $33 |
Operator Amtrak | Departure Time 06:00PM | Arrival Time 08:59PM | Duration 2h59 | Departure days Sun | Cheapest price $33 |
Operator Amtrak | Departure Time 07:00PM | Arrival Time 09:59PM | Duration 2h59 | Departure days Sun | Cheapest price $33 |
Operator Greyhound | Departure Time 07:00PM | Arrival Time 09:20PM | Duration 2h20 | Departure days Thu, Fri, Sat, Sun | Cheapest price $28 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 09:20PM | Duration 1h45 | Departure days Thu, Fri, Sat, Sun | Cheapest price $26 |
Live departures
San Diego, CA to Santa Ana, CA bus times
The table below shows live departures for San Diego, CA to Santa Ana, CA buses for today, Sunday, January 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
3373 AMTRAK · 573 Pacific Surfliner | 5:30 PM Santa Fe Depot, San Diego, CA | 2h29 | 7:59 PM Santa Ana Station, Santa Ana, CA | 1 transfer | |
3477 AMTRAK · 779 Pacific Surfliner | 7:45 PM Santa Fe Depot, San Diego, CA | 3h14 | 10:59 PM Santa Ana Station, Santa Ana, CA | 1 transfer | |
3281 AMTRAK · 581 Pacific Surfliner | 8:45 PM Santa Fe Depot, San Diego, CA | 3h17 | 12:02 AM Santa Ana Station, Santa Ana, CA | 1 transfer | |
3385 AMTRAK · 785 Pacific Surfliner | 11:00 PM Santa Fe Depot, San Diego, CA | 3h02 | 2:02 AM Santa Ana Station, Santa Ana, CA | 1 transfer | |
| Monday, January 12 | |||||
3491 AMTRAK · 591 Pacific Surfliner | 2:00 AM Santa Fe Depot, San Diego, CA | 2h59 | 4:59 AM Santa Ana Station, Santa Ana, CA | 1 transfer | |
![]() | 3:00 AM San Diego, San Ysidro Transit Center | 2h20 | 5:20 AM Santa Ana, E Santa Ana Blvd (Train Station) | 0 transfersDirect | |
3293 AMTRAK · 593 Pacific Surfliner | 3:00 AM Santa Fe Depot, San Diego, CA | 2h59 | 5:59 AM Santa Ana Station, Santa Ana, CA | 1 transfer | |
![]() | 3:35 AM San Diego, Congress Street (Old Town Park), CA | 1h45 | 5:20 AM Santa Ana, E Santa Ana Blvd (Train Station) | 0 transfersDirect | |
![]() | 2:15 PM San Diego, CA | 1h55 | 4:10 PM Santa Ana, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to Santa Ana, CA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 12
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Jan 18
Journey information
Overview: Bus from San Diego, CA to Santa Ana, CA
Buses from San Diego, CA to Santa Ana, CA run on average 10 times per day, taking around 2h 12m. Cheap bus tickets for this journey start at $16 (€13) if you book in advance.
There are 9 buses per day. The earliest bus runs at 00:05, the last at 23:35. The fastest bus covers the 82 miles (132 km) distance in 1h 55m.
Distance 82 miles (132 km) |
Average bus duration 2h 12m |
Cheapest ticket price $16 (€13) |
Buses per day 10 |
Direct buses 9 |
Fastest bus 1h 55m |
First bus 00:05 |
Last bus 23:35 |
Bus providers: Greyhound, FlixBus, Infobus from San Diego, CA to Santa Ana, CAYou can travel by bus between San Diego, CA to Santa Ana, CA with Greyhound, FlixBus, Infobus for as low as $16 (€13). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Greyhound
FAQs: Bus from San Diego, CA to Santa Ana, CA
Find answers to the most common questions about traveling from San Diego, CA to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
To find the cheapest bus tickets for your trip from San Diego, CA to Santa Ana, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- 10€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Infobus
- Small pets allowed in carriers
- Larger pets may require a separate ticket.
popular bus stations
Popular bus stations from San Diego, CA to Santa Ana, CA
More options for your journey from San Diego, CA to Santa Ana, CA
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