4.9
4.6The cheapest and fastest buses from San Francisco, CA to Santa Ana, CA
Cheapest price
$65
Average price
$90
Fastest journey
11 h 20 m
Average duration
12 h 3 m
Buses per day
3
Distance
608 km
The best way to find a cheap bus ticket from San Francisco, CA to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Francisco, CA to Santa Ana, CA will cost around $90 if you buy it on the day, but the cheapest tickets can be found for only $65.
Of the 3 buses that leave San Francisco, CA for Santa Ana, CA on Tue, Jun 02, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 02 the direct buses cover the 608 km distance in an average of 12 h 3 m but if you time it right, some buses will get you there in just 11 h 20 m .
On Tue, Jun 02 the slowest buses will take 12 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:35 AM12h25San Francisco, CA7:00 PMSanta Ana, CA$651One-way0 transfers- 5:35 AM12h25San Francisco, CA6:00 PMSanta Ana, CA$681One-way0 transfers
5:40 AM11h20San Francisco, CA5:00 PMSanta Ana, CA$1381One-way0 transfers
- 5:40 AM11h20San Francisco, CA5:00 PMSanta Ana, CA$1381One-way0 transfers
- 6:35 AM12h25San Francisco, CA7:00 PMSanta Ana, CA$651One-way0 transfers
- 5:35 AM12h25San Francisco, CA6:00 PMSanta Ana, CA$681One-way0 transfers
Travel Information
Compare bus, train, and flight for San Francisco, CA to Santa Ana, CA
Omio recommends booking the train as it is the most popular option from San Francisco, CA to Santa Ana, CA among Omio's users. If you are prioritising price take the train with prices starting from $66. For those with little time consider booking a flight which can get you there in 1h 33m. The ticket price range depends on the travel mode: a train costs an average of $66, and a flight costs an average of $136.
Distance: 377 miles (608 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$80 Average price | $68 Average price Cheapest | $292 Average price | $85 Average price (fuel + tolls) |
11h 57m Average total duration 11h 27m Onboard + 30m Additional time* | 12h 1m Average total duration 11h 31m Onboard + 30m Additional time* | 4h 33m Average total duration Fastest 1h 33m Onboard + 3h 0m Additional time* | 6h 17m Average total duration (door-to-door) |
Most popular bus company | Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Francisco, CA to Santa Ana, CA:
A train is $12 (€9) less than a bus for this route with tickets for a bus from San Francisco, CA to Santa Ana, CA costing on average $80 (€64).
A train is $224 (€180) less than a flight for this route with tickets for a flight from San Francisco, CA to Santa Ana, CA costing on average $292 (€235).
Other travel options to Santa Ana, CA take longer:
Bus takes on average 11h 27m.
Train takes on average 11h 31m.
Tickets start at around $80 (€64) compared to roughly $85 (€69) in fuel and tolls — a saving of about $6 (€4). The journey takes 11h 27m versus 6h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
San Francisco, CA to Santa Ana, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 05:35AM | Arrival Time 06:00PM | Duration 12h25 | Departure days Tue, Thu | Cheapest price $66 |
Operator Greyhound | Departure Time 05:40AM | Arrival Time 05:00PM | Duration 11h20 | Departure days Tue | Cheapest price $138 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 10:00PM | Duration 15h30 | Departure days Tue, Fri, Sat, Sun | Cheapest price $78 |
Operator Amtrak | Departure Time 06:35AM | Arrival Time 07:00PM | Duration 12h25 | Departure days Tue, Thu, Fri | Cheapest price $65 |
Operator Greyhound | Departure Time 06:40AM | Arrival Time 06:00PM | Duration 11h20 | Departure days Thu, Fri | Cheapest price $125 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 10:00PM | Duration 14h30 | Departure days Tue | Cheapest price $71 |
Operator Amtrak | Departure Time 07:45AM | Arrival Time 09:00PM | Duration 13h15 | Departure days Tue, Fri, Sat, Sun | Cheapest price $66 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 05:00AM | Duration 15h30 | Departure days Wed | Cheapest price $43 |
Operator Amtrak | Departure Time 02:45PM | Arrival Time 04:00AM | Duration 13h15 | Departure days Thu | Cheapest price $66 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 10:00AM | Duration 11h30 | Departure days Tue, Fri, Sat, Sun | Cheapest price $100 |
Operator Amtrak | Departure Time 10:35PM | Arrival Time 11:00AM | Duration 12h25 | Departure days Tue, Fri, Sat, Sun | Cheapest price $66 |
Live departures
San Francisco, CA to Santa Ana, CA bus times
The table below shows live departures for San Francisco, CA to Santa Ana, CA buses for today, Sunday, May 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 10:30 PM San Francisco, Transit Center Bay 29 | 11h30 | 10:00 AM Santa Ana, E Santa Ana Blvd (Train Station) | 0 transfersDirect | |
| 4770 AMTRAK · 770 Pacific Surfliner | 10:35 PM San Francisco, CA | 12h25 | 11:00 AM Santa Ana Station, Santa Ana, CA | 1 transfer | |
| Monday, June 1 | |||||
| 5:35 AM San Francisco, CA | 12h25 | 6:00 PM Santa Ana, CA | 0 transfersDirect | |
| 5:40 AM San Francisco, CA | 11h20 | 5:00 PM Santa Ana, CA | 0 transfersDirect | |
| 6:35 AM San Francisco, CA | 12h25 | 7:00 PM Santa Ana, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets San Francisco, CA to Santa Ana, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 01
Jun 02
Jun 03
Jun 04
Jun 05
Jun 06
Jun 07
Why should you book San Francisco, CA to Santa Ana, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from San Francisco, CA to Santa Ana, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from San Francisco, CA to Santa Ana, CA.
Journey information
Overview: Bus from San Francisco, CA to Santa Ana, CA
USAUSA
Buses from San Francisco, CA to Santa Ana, CA run on average 13 times per day, taking around 11h 27m. Cheap bus tickets for this journey start at $43 (€34) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 377 miles (608 km) distance in 11h 20m.
Distance 377 miles (608 km) |
Average bus duration 11h 27m |
Cheapest ticket price $43 (€34) |
Buses per day 13 |
Direct buses 1 |
Fastest bus 11h 20m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 7 days |
Bus providers: Greyhound from San Francisco, CA to Santa Ana, CAYou can travel by bus between San Francisco, CA to Santa Ana, CA with Greyhound for as low as $43 (€34). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from San Francisco, CA to Santa Ana, CA
Find answers to the most common questions about traveling from San Francisco, CA to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Francisco, CA to Santa Ana, CA
Most popular bus connections from San Francisco, CA
More options for your journey from San Francisco, CA to Santa Ana, CA
Here are some other resources that might have the information you need
Most popular buses to and from Santa Ana, CA and San Francisco, CA
Most popular bus connections to Santa Ana, CA
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