The cheapest and fastest buses from Portland, OR to Santa Ana, CA
Cheapest price
$224
Average price
$224
Fastest journey
1 d 2 h
Average duration
1 d 2 h
Buses per day
1
Distance
1372 km
The best way to find a cheap bus ticket from Portland, OR to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Portland, OR to Santa Ana, CA will cost around $224 if you buy it on the day, but the cheapest tickets can be found for only $224.
It's difficult to get from Portland, OR to Santa Ana, CA without transferring at least once.


Travel Information
Compare train, bus, and flight for Portland, OR to Santa Ana, CA
Omio recommends booking the train as it is the most popular option from Portland, OR to Santa Ana, CA among Omio's users. If you are prioritising price take the train with prices starting from $182. For those with little time consider booking a flight which can get you there in 5h 47m. The ticket price range depends on the travel mode: a train costs an average of $182, and a bus costs an average of $198.
Distance: 852 miles (1372 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$249 Average price | $189 Average price Cheapest | $239 Average price |
26h 33m Average total duration 26h 3m Onboard + 30m Additional time* | 32h 9m Average total duration 31h 39m Onboard + 30m Additional time* | 8h 47m Average total duration Fastest 5h 47m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Portland, OR to Santa Ana, CA bus times
The table below shows live departures for Portland, OR to Santa Ana, CA buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 PM Portland, OR | 26h00 | 10:00 PM Santa Ana, CA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Portland, OR to Santa Ana, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Portland, OR to Santa Ana, CA buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Portland, OR to Santa Ana, CA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Portland, OR to Santa Ana, CA.
Journey information
Overview: Bus from Portland, OR to Santa Ana, CA
Buses from Portland, OR to Santa Ana, CA run on average 2 times per day, taking around 26h 3m. Cheap bus tickets for this journey start at $198 (€161) but you can travel from only $182 (€147) by train.
The earliest bus runs at 02:00, the last at 21:20. The fastest bus covers the 852 miles (1372 km) distance in 26h 0m.
Distance 852 miles (1372 km) |
Average bus duration 26h 3m |
Cheapest ticket price $198 (€161) |
Buses per day 2 |
Fastest bus 26h 0m |
First bus 02:00 |
Last bus 21:20 |
Bus providers: FlixBus from Portland, OR to Santa Ana, CAYou can travel by bus between Portland, OR to Santa Ana, CA with FlixBus for as low as $182 (€147). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Portland, OR to Santa Ana, CA
Find answers to the most common questions about traveling from Portland, OR to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Portland, OR to Santa Ana, CA
Most popular bus connections from Portland, OR
More options for your journey from Portland, OR to Santa Ana, CA
Here are some other resources that might have the information you need
