- Must visit
Bowers Museum
Major Orange County museum campus with art exhibitions, family programs, and rotating contemporary and historical shows.
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The cheapest and fastest buses from Cleveland, OH to Santa Ana, CA
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
€194
Average ticket price on Sep 20
€210
Fastest journey on Sep 20
2 d 15 h
Average journey duration on Sep 20
3 d 17 m
Buses on Sep 20
3
Distance
3274 km
Cheap tickets
The best way to find a cheap bus ticket from Cleveland, OH to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cleveland, OH to Santa Ana, CA will cost around €210 if you buy it on the day, but the cheapest tickets can be found for only €194.
Fast buses
It's difficult to get from Cleveland, OH to Santa Ana, CA without transferring at least 3 times.
· · · 3:50 PM67h10Cleveland, Chester Ave At the Greyhound Station (South Side)8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)€1941One-way5 transfers
FlixBus · FlixBus+ · 8:20 PM86h40Cleveland, Chester Ave At the Greyhound Station (South Side)8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)€2161One-way4 transfers- FlixBus · FlixBus+ · 7:30 AM63h00Cleveland, Chester Ave At the Greyhound Station (South Side)7:30 PMSanta Ana, E Santa Ana Blvd (Train Station)€2181One-way3 transfers
- FlixBus · FlixBus+ · 7:30 AM63h00Cleveland, Chester Ave At the Greyhound Station (South Side)7:30 PMSanta Ana, E Santa Ana Blvd (Train Station)€2181One-way3 transfers
- · · · 3:50 PM67h10Cleveland, Chester Ave At the Greyhound Station (South Side)8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)€1941One-way5 transfers
- FlixBus · FlixBus+ · 8:20 PM86h40Cleveland, Chester Ave At the Greyhound Station (South Side)8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)€2161One-way4 transfers
Travel Information
Compare train and bus for Cleveland, OH to Santa Ana, CA
Omio recommends booking the flight as it is the most popular option from Cleveland, OH to Santa Ana, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €209 For those with little time, consider booking a flight, which has an average total journey time of 8h 48m. Average ticket prices depend on the travel mode: a bus costs an average of €209, while a flight costs an average of €517.
Distance: 2034 miles (3274 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
€209 Average price Cheapest | €517 Average price | €393 Average price (fuel + tolls) |
52h 50m Average total duration 52h 20m Onboard + 30m Additional time* | 8h 48m Average total duration Fastest 6h 48m Onboard + 2h 0m Additional time* | 34h 2m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Cleveland, OH to Santa Ana, CA is a bus with an average price of €209.
This is compared to other travel options from Cleveland, OH to Santa Ana, CA:
A bus is €308 less than a flight for this route with tickets for a flight from Cleveland, OH to Santa Ana, CA costing on average €517.
The fastest way to travel from Cleveland, OH to Santa Ana, CA is by flight with an average journey time of 6h 48m.
Other travel options to Santa Ana, CA take longer:
Bus takes on average 52h 20m.
It's helpful to compare your options as there are 2 ways to travel between Cleveland, OH and Santa Ana, CA including taking a train and bus.
We recommend using the bus as it is the most popular way to get from Cleveland, OH to Santa Ana, CA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €209 compared to roughly €393 in fuel and tolls — a saving of about €184. The journey takes 52h 20m versus 34h 2m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Cleveland, OH to Santa Ana, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:25AM | Arrival Time 07:30PM | Duration 66h05 | Departure days Tue, Wed | Cheapest price €196 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 07:30PM | Duration 63h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €198 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 08:00AM | Duration 67h10 | Departure days Everyday | Cheapest price €190 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 08:00AM | Duration 86h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price €216 |
Live departures
Cleveland, OH to Santa Ana, CA bus times
The table below shows live departures for Cleveland, OH to Santa Ana, CA buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus+ · | 7:30 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 63h00 | 7:30 PM Santa Ana, E Santa Ana Blvd (Train Station) | 3 transfers | |
| · · · | 3:50 PM Cleveland, Chester Ave At the Greyhound Station (South Side) | 67h10 | 8:00 AM Santa Ana, E Santa Ana Blvd (Train Station) | 5 transfers | |
| FlixBus · FlixBus+ · | 8:20 PM Cleveland, Chester Ave At the Greyhound Station (South Side) | 86h40 | 8:00 AM Santa Ana, E Santa Ana Blvd (Train Station) | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Cleveland, OH to Santa Ana, CA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Cleveland, OH to Santa Ana, CA buses with Omio?
Greyhound operates all buses services from Cleveland, OH to Santa Ana, CA.
Omio is an official ticket reseller for all your travel options from Cleveland, OH to Santa Ana, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Cleveland, OH to Santa Ana, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Cleveland, OH to Santa Ana, CA.
Journey information
Overview: Bus from Cleveland, OH to Santa Ana, CA
USAUSA
Buses from Cleveland, OH to Santa Ana, CA run on average 2 times per day, taking around 52h 20m. Cheap bus tickets for this journey start at €190 if you book in advance.
The earliest bus runs at 18:04, the last at 18:04. The fastest bus covers the 2034 miles (3274 km) distance in 50h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 2034 miles (3274 km) |
Average bus duration 52h 20m |
Cheapest ticket price €190 |
Buses per day 2 |
Fastest bus 50h 45m |
First bus 6:04 PM |
Last bus 6:04 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Cleveland, OH to Santa Ana, CAYou can travel by bus between Cleveland, OH to Santa Ana, CA with Greyhound for as low as €190. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
50h 45m
Cheapest Greyhound Price
€190
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Santa Ana, CA
Things to do in Santa Ana, CA
Discover the best of Santa Ana, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santa Ana, CA trip today.
- Recommended
Discovery Cube Orange County
Hands-on science museum with interactive exhibits, a Discovery Cube, and family-friendly learning in downtown Santa Ana.
- Recommended
Lyon Air Museum
Small local museum preserving Orange County aviation and aerospace history with artifacts, photos, and volunteer-led interpretation.
- Must visit
Downtown Santa Ana
Walkable downtown district with historic buildings, murals, shops, galleries, and regular arts and community events.
- Recommended
East 4th Street
Lively pedestrian-friendly arts corridor known for galleries, murals, boutiques, and monthly art-focused street activity.
- Recommended
Floral Park
Historic neighborhood of preserved early 20th-century homes, ideal for architecture walks and seasonal house tours.
FAQs: Bus from Cleveland, OH to Santa Ana, CA
Find answers to the most common questions about traveling from Cleveland, OH to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Cleveland, OH to Santa Ana, CA can start from as little as €190 when you book in advance. The average bus ticket price for Cleveland, OH to Santa Ana, CA is €209 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Cleveland, OH to Santa Ana, CA is 50h 45m to travel the 2034 miles (3274 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Cleveland, OH to Santa Ana, CA leaves at 6:04 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Cleveland, OH to Santa Ana, CA leaves at 6:04 PM.
There are 2 buses a day from Cleveland, OH to Santa Ana, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Cleveland, OH to Santa Ana, CA, you can count on Greyhound for the best way to get you to Santa Ana, CA. You can also check all possible bus companies who offer a service between Cleveland, OH and Santa Ana, CA and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Cleveland, Chester Ave At the Greyhound Station (South Side), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Santa Ana, E Santa Ana Blvd (Train Station), located 1 away from the city centre.
A trip to Santa Ana, CA from Cleveland, OH is worth doing but not as a day trip with a journey time of 50h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Cleveland, OH to Santa Ana, CA is February.
It's helpful to compare your options as there are 2 ways to travel between Cleveland, OH and Santa Ana, CA including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Cleveland, OH to Santa Ana, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Cleveland, OH to Santa Ana, CA for bus company Greyhound.
Whether you can cancel your bus ticket from Cleveland, OH to Santa Ana, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Cleveland, OH to Santa Ana, CA.
Yes, the following luggage options are included when booking a bus ticket from Cleveland, OH to Santa Ana, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Cleveland, OH to Santa Ana, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Cleveland, OH to Santa Ana, CA.
You can reserve your seat on the bus from Cleveland, OH to Santa Ana, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Cleveland, OH to Santa Ana, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Cleveland, OH to Santa Ana, CA with the following bus company: Greyhound.
Since neither Cleveland, OH nor Santa Ana, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Cleveland, OH to Santa Ana, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Santa Ana, CA, travelers should be alert to petty crimes such as pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by unlicensed taxi or ride-share drivers and street vendors selling counterfeit goods. Staying in well-populated areas, using official transportation services, and safeguarding personal belongings help minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Cleveland, OH to Santa Ana, CA
Most Cleveland, OH to Santa Ana, CA buses use the Cleveland, Chester Ave At the Greyhound Station (South Side) to Santa Ana, E Santa Ana Blvd (Train Station) station pair. Use this guide to compare Cleveland, OH and Santa Ana, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Cleveland
Arrival bus stations in Santa Ana
Which Cleveland, OH station do buses to Santa Ana, CA leave from?
Buses from Cleveland, OH to Santa Ana, CA leave from Cleveland, Chester Ave At the Greyhound Station (South Side). The station is 0 miles (1 km) from Cleveland, OH city centre at Cleveland, Cleveland, OH 44114, USA.
Cleveland, Chester Ave At the Greyhound Station (South Side)Cleveland, Cleveland, OH 44114, USA
City-centre transport
Getting to Cleveland, Chester Ave At the Greyhound Station (South Side) from Cleveland city centre
Cleveland, Chester Ave At the Greyhound Station (South Side) is 1 km from Cleveland city centre. Public transport options include:
BusHl · 15m · €3 · every ~10 min
Hl · 16m · €3 · every ~10 min
Cleveland, Chester Ave At the Greyhound Station (South Side) bus station facilities and services
Cleveland, Chester Ave At the Greyhound Station (South Side) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack bar available onsite.
Wi-Fi and ATMs
Free WiFi available for passengers. ATMs are available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Tickets and information
Ticket office support is available at Cleveland, Chester Ave At the Greyhound Station (South Side).
Parking, taxis and toilets
Available at Cleveland, Chester Ave At the Greyhound Station (South Side): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Cleveland, Chester Ave At the Greyhound Station (South Side): Station is wheelchair accessible.
Which Santa Ana, CA station do buses from Cleveland, OH arrive at?
Buses from Cleveland, OH to Santa Ana, CA arrive at Santa Ana, E Santa Ana Blvd (Train Station). Santa Ana, E Santa Ana Blvd (Train Station) is 0 miles (1 km) from Santa Ana, CA city centre.
Santa Ana, E Santa Ana Blvd (Train Station)Santa Ana, 1000 E Santa Ana Blvd, Santa Ana, CA 92701, USA
City-centre transport
Getting to Santa Ana, E Santa Ana Blvd (Train Station) from Santa Ana city centre
Santa Ana, E Santa Ana Blvd (Train Station) is 1 km from Santa Ana city centre. Public transport options include:
TRUE
Santa Ana, E Santa Ana Blvd (Train Station) bus station facilities and services
Santa Ana, E Santa Ana Blvd (Train Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Santa Ana, E Santa Ana Blvd (Train Station). ATMs are available at Santa Ana, E Santa Ana Blvd (Train Station).
Tickets and information
Ticket office support is available at Santa Ana, E Santa Ana Blvd (Train Station).
Parking, taxis and toilets
Available at Santa Ana, E Santa Ana Blvd (Train Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Santa Ana, E Santa Ana Blvd (Train Station): Bus access is available.
Most popular bus connections from Cleveland, OH
More options for your journey from Cleveland, OH to Santa Ana, CA
Here are some other resources that might have the information you need
Most popular buses to and from Santa Ana, CA and Cleveland, OH
Most popular bus connections to Santa Ana, CA
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