Denver, CO to Santa Ana, CA bus with Greyhound

Fri, Mar 06
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The cheapest and fastest buses from Denver, CO to Santa Ana, CA

Showing times and prices for Mar 07

Cheapest price

$424

Average price

$424

Fastest journey

1 d 25 m

Average duration

1 d 25 m

Buses per day

1

Distance

1325 km

Cheap tickets

The best way to find a cheap bus ticket from Denver, CO to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Denver, CO to Santa Ana, CA will cost around $424 if you buy it on the day, but the cheapest tickets can be found for only $424.

Fast buses

It's difficult to get from Denver, CO to Santa Ana, CA without transferring at least once.

Greyhound USA
11:05AM24h25
Denver, CO
11:30AMSanta Ana, CA
$4241One-way
1 transfer

Travel Information

Compare bus, train, and flight for Denver, CO to Santa Ana, CA

Omio recommends booking the bus as it is the most popular option from Denver, CO to Santa Ana, CA among Omio's users. If you are prioritising price take the bus with prices starting from $146. For those with little time consider booking a flight which can get you there in 2h 32m. The ticket price range depends on the travel mode: a bus costs an average of $146, and a train costs an average of $318.

Distance: 823 miles (1325 km)

Compare bus with

Most popular
Bus
Train
Flight

$228

Average price

Cheapest

$706

Average price

$308

Average price

23h 30m

Average total duration

23h 0m

Onboard

+

30m

Additional time*

44h 24m

Average total duration

43h 54m

Onboard

+

30m

Additional time*

5h 32m

Average total duration

Fastest

2h 32m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Denver, CO to Santa Ana, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
11:05AM
Arrival Time
11:30AM
Duration
25h25
Departure days
Fri
Cheapest price
$198
Operator
Greyhound
Departure Time
07:00PM
Arrival Time
08:00AM
Duration
37h00
Departure days
Fri
Cheapest price
$200
Operator
Greyhound
Departure Time
08:10PM
Arrival Time
11:30AM
Duration
39h20
Departure days
Fri
Cheapest price
$223

Live departures

Denver, CO to Santa Ana, CA bus times

The table below shows live departures for Denver, CO to Santa Ana, CA buses for today, Friday, March 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at 9:08 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhoundundefined · undefined6:05 PM Denver, Union Station
25h25
7:30 PM Santa Ana, E Santa Ana Blvd (Train Station)1 transfer
Saturday, March 7
greyhoundundefined · undefined · undefined · undefined2:00 AM Denver, Union Station
37h00
3:00 PM Santa Ana, E Santa Ana Blvd (Train Station)4 transfers
greyhoundundefined · undefined · undefined · undefined3:10 AM Denver, Union Station
39h20
6:30 PM Santa Ana, E Santa Ana Blvd (Train Station)4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Denver, CO to Santa Ana, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Mar 07
Sun
Mar 08
Mon
Mar 09
Tue
Mar 10
Wed
Mar 11
Thu
Mar 12
Fri
Mar 13

Why should you book Denver, CO to Santa Ana, CA buses with Omio?

Greyhound operates all buses services from Denver, CO to Santa Ana, CA.
Omio is an official ticket reseller for all your travel options from Denver, CO to Santa Ana, CA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Denver, CO to Santa Ana, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Denver, CO to Santa Ana, CA.

Journey information

Overview: Bus from Denver, CO to Santa Ana, CA

USAUSA
USAUSA
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Buses from Denver, CO to Santa Ana, CA run on average 3 times per day, taking around 23h 0m. Cheap bus tickets for this journey start at $146 (€118) if you book in advance.

The earliest bus runs at 08:46, the last at 21:20. The fastest bus covers the 823 miles (1325 km) distance in 38h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
823 miles (1325 km)
Average bus duration
23h 0m
Cheapest ticket price
$146 (€118)
Buses per day
3
Fastest bus
38h 10m
First bus
08:46
Last bus
21:20
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Denver, CO to Santa Ana, CAYou can travel by bus between Denver, CO to Santa Ana, CA with Greyhound for as low as $146 (€118). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
38h 10m
Cheapest Price
$146 (€118)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Denver, CO to Santa Ana, CA

Find answers to the most common questions about traveling from Denver, CO to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Denver, CO to Santa Ana, CA can start from as little as $146 (€118) when you book in advance. The average bus ticket price for Denver, CO to Santa Ana, CA is $228 (€185) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Denver, CO to Santa Ana, CA is 38h 10m to travel the 823 miles (1325 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Denver, CO to Santa Ana, CA leaves at 8:46 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Denver, CO to Santa Ana, CA leaves at 9:20 PM.
There are 3 buses a day from Denver, CO to Santa Ana, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Denver, CO to Santa Ana, CA, you can count on Greyhound for the best way to get you to Santa Ana, CA. You can also check all possible bus companies who offer a service between Denver, CO and Santa Ana, CA and compare the amenities they offer before buying a bus ticket.
A trip to Santa Ana, CA from Denver, CO is worth doing but not as a day trip with a journey time of 38h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Denver, CO to Santa Ana, CA is September.
It's helpful to compare your options as there are 3 ways to travel between Denver, CO and Santa Ana, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Denver, CO to Santa Ana, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Denver, CO to Santa Ana, CA for bus company Greyhound.
Whether you can cancel your bus ticket from Denver, CO to Santa Ana, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Denver, CO to Santa Ana, CA.
Yes, the following luggage options are included when booking a bus ticket from Denver, CO to Santa Ana, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Denver, CO to Santa Ana, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Denver, CO to Santa Ana, CA.
You can reserve your seat on the bus from Denver, CO to Santa Ana, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Denver, CO to Santa Ana, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Denver, CO to Santa Ana, CA with the following bus company: Greyhound.

popular bus stations

Popular bus stations from Denver, CO to Santa Ana, CA

Denver
Santa Ana
The major bus station for departures in Denver is Denver, Union Station. Find all the information you need to know about services, amenities and connections at Denver, Union Station for your trip from Denver to Santa Ana.
Denver, Union Station
information

Most popular bus connections to Santa Ana, CA

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