Denver, CO to Santa Ana, CA bus with Greyhound

Tue, Apr 21
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The cheapest and fastest buses from Denver, CO to Santa Ana, CA

Showing times and prices for Apr 22

Cheapest price

$148

Average price

$148

Fastest journey

1 d 14 h 10 m

Average duration

1 d 14 h 10 m

Buses per day

1

Distance

1325 km

Cheap tickets

The best way to find a cheap bus ticket from Denver, CO to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Denver, CO to Santa Ana, CA will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $148.

Fast buses

Of the 1 buses that leave Denver, CO for Santa Ana, CA on Wed, Apr 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Apr 22 the direct buses cover the 1325 km distance in an average of 1 d 14 h 10 m but if you time it right, some buses will get you there in just 1 d 14 h 10 m .

On Wed, Apr 22 the slowest buses will take 1 d 14 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    2:00 AM38h10
    Denver, CO
    4:10 PMSanta Ana, CA
    $1481One-way
    0 transfers

Travel Information

Compare bus, train, and flight for Denver, CO to Santa Ana, CA

Omio recommends booking the bus as it is the most popular option from Denver, CO to Santa Ana, CA among Omio's users. If you are prioritising price take the bus with prices starting from $148. For those with little time consider booking a flight which can get you there in 2h 32m. The ticket price range depends on the travel mode: a bus costs an average of $148, and a train costs an average of $323.

Distance: 823 miles (1325 km)

Compare bus with

Most popular
Bus
Flight
Train

$231

Average price

Cheapest

$312

Average price

$716

Average price

23h 30m

Average total duration

23h 0m

Onboard

+

30m

Additional time*

5h 32m

Average total duration

Fastest

2h 32m

Onboard

+

3h 0m

Additional time*

44h 24m

Average total duration

43h 54m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Denver, CO to Santa Ana, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
11:05AM
Arrival Time
11:30AM
Duration
25h25
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$187
Operator
Greyhound
Departure Time
07:00PM
Arrival Time
08:00AM
Duration
38h00
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$185
Operator
Greyhound
Departure Time
08:10PM
Arrival Time
11:30AM
Duration
40h20
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$187

Live departures

Denver, CO to Santa Ana, CA bus times

The table below shows live departures for Denver, CO to Santa Ana, CA buses for today, Monday, April 20. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
greyhoundundefined · undefined11:05 AM Denver, Union Station
25h25
11:30 AM Santa Ana, E Santa Ana Blvd (Train Station)1 transfer
Tuesday, April 21
greyhoundundefined · undefined · undefined7:00 PM Denver, Union Station
38h00
8:00 AM Santa Ana, E Santa Ana Blvd (Train Station)2 transfers
greyhound2:00 AM Denver, CO
38h10
4:10 PM Santa Ana, CA0 transfersDirect
greyhoundundefined · undefined · undefined · undefined8:10 PM Denver, Union Station
40h20
11:30 AM Santa Ana, E Santa Ana Blvd (Train Station)4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Denver, CO to Santa Ana, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Apr 21
Wed
Apr 22
Thu
Apr 23
Fri
Apr 24
Sat
Apr 25
Sun
Apr 26
Mon
Apr 27

Why should you book Denver, CO to Santa Ana, CA buses with Omio?

Greyhound operates all buses services from Denver, CO to Santa Ana, CA.
Omio is an official ticket reseller for all your travel options from Denver, CO to Santa Ana, CA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Denver, CO to Santa Ana, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Denver, CO to Santa Ana, CA.

Journey information

Overview: Bus from Denver, CO to Santa Ana, CA

USAUSA
USAUSA
Icon of bus

Buses from Denver, CO to Santa Ana, CA run on average 3 times per day, taking around 23h 0m. Cheap bus tickets for this journey start at $148 (€118) if you book in advance.

The earliest bus runs at 08:46, the last at 21:20. The fastest bus covers the 823 miles (1325 km) distance in 38h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
823 miles (1325 km)
Average bus duration
23h 0m
Cheapest ticket price
$148 (€118)
Buses per day
3
Fastest bus
38h 10m
First bus
8:46 AM
Last bus
9:20 PM
Cheapest Month
Sep
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Denver, CO to Santa Ana, CAYou can travel by bus between Denver, CO to Santa Ana, CA with Greyhound for as low as $148 (€118). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
38h 10m
Cheapest Price
$148 (€118)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Denver, CO to Santa Ana, CA

Find answers to the most common questions about traveling from Denver, CO to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Denver, CO to Santa Ana, CA can start from as little as $148 (€118) when you book in advance. The average bus ticket price for Denver, CO to Santa Ana, CA is $231 (€185) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Denver, CO to Santa Ana, CA is 38h 10m to travel the 823 miles (1325 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Denver, CO to Santa Ana, CA leaves at 8:46 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Denver, CO to Santa Ana, CA leaves at 9:20 PM.
There are 3 buses a day from Denver, CO to Santa Ana, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Denver, CO to Santa Ana, CA, you can count on Greyhound for the best way to get you to Santa Ana, CA. You can also check all possible bus companies who offer a service between Denver, CO and Santa Ana, CA and compare the amenities they offer before buying a bus ticket.
A trip to Santa Ana, CA from Denver, CO is worth doing but not as a day trip with a journey time of 38h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Denver, CO to Santa Ana, CA is September.
It's helpful to compare your options as there are 3 ways to travel between Denver, CO and Santa Ana, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Denver, CO to Santa Ana, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Denver, CO to Santa Ana, CA for bus company Greyhound.
Whether you can cancel your bus ticket from Denver, CO to Santa Ana, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Denver, CO to Santa Ana, CA.
Yes, the following luggage options are included when booking a bus ticket from Denver, CO to Santa Ana, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Denver, CO to Santa Ana, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Denver, CO to Santa Ana, CA.
You can reserve your seat on the bus from Denver, CO to Santa Ana, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Denver, CO to Santa Ana, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Denver, CO to Santa Ana, CA with the following bus company: Greyhound.
Since neither Denver, CO nor Santa Ana, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Denver, CO to Santa Ana, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Santa Ana, CA, travelers should be alert to petty crimes such as pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by unlicensed taxi or ride-share drivers and street vendors selling counterfeit goods. Staying in well-populated areas, using official transportation services, and safeguarding personal belongings help minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Denver, CO to Santa Ana, CA

Denver
Santa Ana
The major bus station for departures in Denver is Denver, Union Station. Find all the information you need to know about services, amenities and connections at Denver, Union Station for your trip from Denver to Santa Ana.
Denver, Union Station
information

Most popular bus connections to Santa Ana, CA

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