Chicago, IL to Santa Ana, CA bus

Thu, May 07
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Chicago, IL to Santa Ana, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
10:15AM
Arrival Time
07:30PM
Duration
59h15
Departure days
Mon
Cheapest price
$220
Operator
Greyhound
Departure Time
12:25PM
Arrival Time
11:30AM
Duration
49h05
Departure days
Mon
Cheapest price
$230
Operator
Greyhound
Departure Time
05:15PM
Arrival Time
07:30PM
Duration
52h15
Departure days
Mon
Cheapest price
$225
Operator
Greyhound
Departure Time
11:10PM
Arrival Time
08:00AM
Duration
58h50
Departure days
Mon
Cheapest price
$214

Journey information

Overview: Bus from Chicago, IL to Santa Ana, CA

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Take a bus from Chicago, IL to Santa Ana, CA and enjoy the approximately 1731 miles (2787 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 07:40, the last at 23:10.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1731 miles (2787 km)
Buses per day
2
First bus
7:40 AM
Last bus
11:10 PM
Cheapest Month
Sep
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Jan - Mar
Best time to book
1 day
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Chicago, IL to Santa Ana, CA

Find answers to the most common questions about traveling from Chicago, IL to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Chicago, IL to Santa Ana, CA leaves at 7:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to Santa Ana, CA leaves at 11:10 PM.
The cheapest month for a bus from Chicago, IL to Santa Ana, CA is September.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and Santa Ana, CA including taking a bus, train, and flight.
No, there are no bathrooms on board the bus from Chicago, IL to Santa Ana, CA.
No, the bus from Chicago, IL to Santa Ana, CA has no accessibility options.
No, bikes are not allowed on board the bus from Chicago, IL to Santa Ana, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Chicago, IL to Santa Ana, CA.
No, luggage for the bus from Chicago, IL to Santa Ana, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Chicago, IL to Santa Ana, CA.
Unfortunately, pets are not allowed on the bus from Chicago, IL to Santa Ana, CA.
No, there are no USB plugs on board the bus from Chicago, IL to Santa Ana, CA.
No, there is no WiFi on board the bus from Chicago, IL to Santa Ana, CA.
Since neither Chicago, IL nor Santa Ana, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Chicago, IL to Santa Ana, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Santa Ana, CA, travelers should be alert to petty crimes such as pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by unlicensed taxi or ride-share drivers and street vendors selling counterfeit goods. Staying in well-populated areas, using official transportation services, and safeguarding personal belongings help minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Chicago, IL to Santa Ana, CA

Chicago
Santa Ana
The major bus station for departures in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip from Chicago to Santa Ana.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information

Most popular bus connections to Santa Ana, CA

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