- Must visit
Greenville County Museum of Art
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Flights from Orlando, FL to Greenville, SC depart on average 19 times per day, taking around 1h 50m. Cheap flight tickets for this journey start at $57 (€46) if you book in advance.
There are 1 flights per day. The earliest flight runs at 05:00, the last at 22:14. The fastest flight covers the 440 miles (709 km) distance in 1h 26m. July is the cheapest month to fly.
Distance 440 miles (709 km) |
Average flight duration 1h 50m |
Cheapest ticket price $57 (€46) |
Flights per day 19 |
Direct flights 1 |
Fastest flight 1h 26m |
First flight 5:00 AM |
Last flight 10:14 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Cheapest price
$57
Average price
$102
Fastest journey
1 h 26 m
Average duration
1 h 28 m
Flights per day
4
Distance
709 km
The best way to find a cheap flight ticket from Orlando, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Greenville, SC will cost around $102 if you buy it on the day, but the cheapest tickets can be found for only $57.
Of the 4 flights that leave Orlando, FL for Greenville, SC onThu, Jun 18, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jun 18 the direct flights cover the 709 km distance in an average of 1 h 28 m but if you time it right, some flights will get you there in just 1 h 26 m .
On Thu, Jun 18 the longest flights will take 1 h 28 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the flight as it is the most popular option from Orlando, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $140.
Distance: 440 miles (709 km)
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$200 Average price | $229 Average price | $128 Average price Cheapest | $102 Average price (fuel + tolls) |
4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 29h 13m Average total duration 28h 43m Onboard + 30m Additional time* | 10h 20m Average total duration 9h 50m Onboard + 30m Additional time* | 7h 37m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Greenville, SC:
A bus is $71 (€58) less than a flight for this route with tickets for a flight from Orlando, FL to Greenville, SC costing on average $200 (€161).
A bus is $101 (€82) less than a train for this route with tickets for a train from Orlando, FL to Greenville, SC costing on average $229 (€185).
Other travel options to Greenville, SC take longer:
Bus takes on average 9h 50m.
Train takes on average 28h 43m.
The table below shows live departures for Orlando, FL to Greenville, SC flights for today, Wednesday, June 17. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:00 AM Orlando, FL | 3h38 | 12:38 PM Greenville, SC | 0 transfersDirect | |
![]() | 2:03 PM Orlando, FL | 4h14 | 6:17 PM Greenville, SC | 0 transfersDirect | |
![]() | 9:33 PM Orlando, FL | 6h21 | 3:54 AM Greenville, SC | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Well-regarded art museum known for American art, including important Andrew Wyeth works and Southern artists. One of the city’s standout cultural stops.
Regional history museum with permanent and rotating exhibits on the people and stories of Upstate South Carolina. A strong choice for understanding Greenville’s local context.
Specialized museum displaying rare historic instruments from around the world. A distinctive local favorite for music, design, and cultural history.
Greenville’s central downtown street lined with shops, public art, plazas, and event spaces. It is the main place to walk and experience the city atmosphere.
Downtown park built around waterfalls, gardens, and river overlooks. It is Greenville’s signature public space and a top stop for first-time visitors.
Popular multi-use greenway for walking and cycling, linking Greenville with nearby communities. Widely loved by locals and visitors for active sightseeing.
Slow-smoked pork, often chopped or pulled, served with the state's signature mustard-based sauce. It is a defining Upstate and South Carolina tradition.
Slices of unripe tomato coated and fried until crisp, often served with remoulade or pimento cheese. A classic Southern starter common in Greenville restaurants.
Creamy stone-ground grits topped with shrimp, gravy, or bacon. This Lowcountry favorite is widely loved in Greenville as part of broader South Carolina cuisine.
Well-regarded neighborhood restaurant focused on seasonal Southern-influenced American cooking with a polished but relaxed atmosphere.
A long-running downtown Greenville favorite serving refined Southern cuisine in a lively, upscale setting. Known for shrimp and grits, brunch, and strong wine selections.
Popular casual spot for barbecue, ribs, and Southern comfort food near Falls Park. Lively atmosphere and a good place to try local smoked meats.
Moderate by U.S. standards: casual dining is affordable, while upscale downtown hotels and restaurants cost more.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, hotel staff a few dollars, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Orlando, FL to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

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