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Journey information
Overview: Orlando, FL to Greenville, SC flight
USAUSA
Flights from Orlando, FL to Greenville, SC depart on average 7 times per day, taking around 2h 2m. Cheap flight tickets for this journey start at $48 (€38) if you book in advance.
There are 1 flights per day. The earliest flight runs at 05:00, the last at 22:14. The fastest flight covers the 440 miles (709 km) distance in 1h 22m. April is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 440 miles (709 km) |
Average flight duration 2h 2m |
Cheapest ticket price $48 (€38) |
Flights per day 7 |
Direct flights 1 |
Fastest flight 1h 22m |
Cheapest month to travel April |
First flight 05:00 |
Last flight 22:14 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Travel Information
Compare bus, train, and flight for Orlando, FL to Greenville, SC
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €60. For those with little time consider booking a flight which can get you there in 2h 2m. The ticket price range depends on the travel mode: a bus costs an average of €60, and a train costs an average of €112.
Distance: 440 miles (709 km)
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
€101 Average price | €151 Average price | €77 Average price Cheapest |
5h 2m Average total duration Fastest 2h 2m Onboard + 3h 0m Additional time* | 29h 13m Average total duration 28h 43m Onboard + 30m Additional time* | 10h 20m Average total duration 9h 50m Onboard + 30m Additional time* |
 Most popular airline |  Most popular train company |  Most popular bus company |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Orlando, FL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Orlando, FL to Greenville, SC flights with Omio?
Breeze Airways as well as American Airlines offer flights services from Orlando, FL to Greenville, SC.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Greenville, SC.
Why book with Omio vs Breeze Airways?
- Compare with other providers: On Omio, you can not only buy tickets for Breeze Airways, but also compare tickets for the likes of American Airlines to find the best option for your trip from Orlando, FL to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Breeze Airways with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Orlando, FL to Greenville, SC.
Why book with Omio over Edreams, Skyscanner or Trip?
- Compare with other providers: On Omio, you can also compare tickets for the likes of American Airlines to find the best option for your trip from Orlando, FL to Greenville, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Orlando, FL to Greenville, SC.
Airlines: American Airlines, Breeze Airways from Orlando, FL to Greenville, SCFind the best flights between Orlando, FL to Greenville, SC with Omio's travel partners American Airlines, Breeze Airways from $48 (€38). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
3h 42m
Cheapest Price
$179 (€142)
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
Breeze Airways
About
Breeze Airways is an American low-cost airline founded by aviation entrepreneur David Neeleman, who also co-founded JetBlue. Launched in May 2021, Breeze focuses on providing affordable, nonstop flights between underserved routes, primarily connecting smaller cities that larger airlines often overlook. The airline operates a fleet of Airbus A220-300 and Embraer 190/195 aircraft, known for their comfortable seating and spacious cabins. Breeze offers various ticket options, including "Nice," "Nicer," and "Nicest" bundles, along with a "No Flex Fare" for those seeking the most basic option. Amenities can include free in-flight entertainment, Wi-Fi on A220 aircraft, and complimentary family seating. As of August 2025, Breeze Airways serves 76 domestic destinations across 31 states.
Luggage & cancellation policy
Average Duration
1h 39m
Cheapest Price
$48 (€38)
Luggage included
One personal item (17 x 13 x 8 inches) included with Nice or Nicer fare
Additional luggage
Checked bags available for purchase. First bag $35-$39, second bag $45, additional bags $80 each
Cancellation Policy
Full refund if cancelled within 24 hours of booking. After that, cancellation fees apply based on fare type
Pregnant on board
Pregnant passengers may travel up to 38 weeks without medical certificate. After 38 weeks, medical certificate required within 72 hours of travel
Unaccompagned minor
Unaccompanied minor service available for ages 5-14. $50 fee per child, per segment. Must be booked by calling reservations
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Breeze provides wheelchair assistance and accommodates passengers with disabilities. Service must be requested at least 48 hours before departure.
Entertaiment on board
FAQs: Orlando, FL to Greenville, SC Flight
Find answers to the most common questions about traveling from Orlando, FL to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Orlando, FL to Greenville, SC can start from as little as $48 (€38) when you book in advance. The average flight ticket price for Orlando, FL to Greenville, SC is $127 (€101) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Orlando, FL to Greenville, SC is 1h 22m to travel the 440 miles (709 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Orlando, FL to Greenville, SC leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Orlando, FL to Greenville, SC leaves at 10:14 PM.
Yes, there are 1 direct flights a day from Orlando, FL to Greenville, SC with . Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Orlando, FL to Greenville, SC, you can count on American Airlines, Breeze Airways for the best way to get you to Greenville, SC. You can also check all possible airlines who offer a service between Orlando, FL and Greenville, SC and compare the amenities they offer before buying a plane ticket.
The cheapest month for a flight from Orlando, FL to Greenville, SC is April.
It's helpful to compare your options as there are 3 ways to travel between Orlando, FL and Greenville, SC including taking a bus, train, and flight.
Since neither Orlando, FL nor Greenville, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between Orlando, FL and Greenville, SC.
The best events to attend in Greenville, SC include:
- Greenville Jazz Festival, a vibrant celebration of jazz music featuring local and national artists performing in various venues
- Artisphere, an annual arts festival showcasing visual arts, live performances, and culinary delights from regional artists
- Fall for Greenville, a food and music festival highlighting the best local cuisine and entertainment in a family-friendly atmosphere.
The best holidays to experience in Greenville, SC include:
- Memorial Day, the unofficial start of summer with vibrant local events and parades
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a perfect time for outdoor activities and community gatherings as summer winds down.
The best season to visit Greenville, SC is Spring or Fall. The best weather to explore Greenville, SC is during April-May or September-October.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
popular airports
Popular airports from Orlando, FL to Greenville, SC
Orlando
Greenville
The major airport for departures in Orlando is Orlando International Airport. Find all the information you need to know about services, amenities and connections at Orlando International Airport for your trip from Orlando to Greenville.
Amenities at airport
Wifi
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Shower
Lounge
Lost and Found Office
Car Rentalinformation
Distance to city center
13 km
Car connection
FL-528 W, exit 11Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops in all terminals, including Duty-Free and Hudson News.
Parking
- Parking available in garages A, B, and C, approximately 1.9€ ($2) per 20 minutes.
Dining
- Restaurants in all terminals, including fast food and sit-down options like McDold's and Outback Steakhouse
Taxis
- Available outside the terminal.
Accessibility
- Ramps, assistance
WC
- Available throughout the airport.
Hotel
- Hyatt Regency located within the airport.
Shower
- Showers available in some lounges.
Lounge
- Lounges available, including Delta Sky Club and United Club.
Lost and Found Office
- Lost and Found located in the Main terminal, Level 3.
Car Rental
- Car rental services available on-site, including Avis and Hertz
Public transit options for Orlando International Airport
- Lynx Bus 11, 42, 51, stop at terminal A/B, 45 minutes to city center
Amenities at airport
WifiShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeCar Rentalinformation
Distance to city center
4 kmCar connection
FL-417 Toll S, exit 49Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops available, located in the terminal, includes Hudson News and gift shops.
Parking
- Parking available with rates starting at approximately 1.42€ ($1.50) per hour.
Dining
- Restaurants available; located in the terminal, options include fast food and sit-down dining like Cheeburger Cheeburger and Cinbon.
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps
WC
- Available throughout the airport.
Hotel
- Hotels nearby, within walking distance, Best Western Plus Sanford Airport/Lake Mary Hotel.
Lounge
- Lounge available, Royal Palm Lounge.
Lost and Found Office
- Lost and Found located in the terminal.
Car Rental
- Car rental services available; companies like Avis, Budget, and Enterprise.
Public transit options for Orlando Sanford International Airport
- Bus line 46E, Sanford SunRail Station, 27 miles
The major airport for arrivals in Greenville is Greenville-Spartanburg International Airport. Find all the information you need to know about services, amenities and connections at Greenville-Spartanburg International Airport for your journey to Greenville from Orlando.
Greenville-Spartanburg International Airport (GSP)
information
More options for your journey from Orlando, FL to Greenville, SC
Here are some other resources that might have the information you need
Most popular flights to and from Greenville, SC and Orlando, FL
Most popular flights to Greenville, SC
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