- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price
$243
Average price
$498
Fastest journey
2 d 18 h 20 m
Average duration
2 d 18 h 20 m
Buses per day
2
Distance
3922 km
The best way to find a cheap bus ticket from Orlando, FL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to San Francisco, CA will cost around $498 if you buy it on the day, but the cheapest tickets can be found for only $243.
Of the 2 buses that leave Orlando, FL for San Francisco, CA on Thu, Jul 23, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 23 the direct buses cover the 3922 km distance in an average of 2 d 18 h 20 m but if you time it right, some buses will get you there in just 2 d 18 h 20 m .
On Thu, Jul 23 the slowest buses will take 2 d 18 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the flight as it is the most popular option from Orlando, FL to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $143. For those with little time consider booking a flight which can get you there in 6h 57m. The ticket price range depends on the travel mode: a bus costs an average of $143, and a train costs an average of $274.
Distance: 2437 miles (3922 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$354 Average price Cheapest | $391 Average price | $1240 Average price | $579 Average price (fuel + tolls) |
68h 1m Average total duration 67h 31m Onboard + 30m Additional time* | 9h 57m Average total duration Fastest 6h 57m Onboard + 3h 0m Additional time* | 99h 43m Average total duration 99h 13m Onboard + 30m Additional time* | 41h 25m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to San Francisco, CA:
A bus is $37 (€31) less than a flight for this route with tickets for a flight from Orlando, FL to San Francisco, CA costing on average $391 (€322).
A bus is $886 (€728) less than a train for this route with tickets for a train from Orlando, FL to San Francisco, CA costing on average $1240 (€1019).
Other travel options to San Francisco, CA take longer:
Bus takes on average 67h 31m.
Train takes on average 99h 13m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:45AM | Arrival Time 07:25PM | Duration 66h40 | Departure days Tue, Wed | Cheapest price $163 |
Operator Greyhound | Departure Time 01:05AM | Arrival Time 07:25PM | Duration 66h20 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $276 |
Operator Greyhound | Departure Time 01:40AM | Arrival Time 02:05AM | Duration 72h25 | Departure days Sun | Cheapest price $213 |
Operator Greyhound | Departure Time 01:45AM | Arrival Time 08:25PM | Duration 66h40 | Departure days Mon, Tue, Wed | Cheapest price $231 |
Operator Greyhound | Departure Time 02:05AM | Arrival Time 08:25PM | Duration 66h20 | Departure days Tue, Wed, Thu | Cheapest price $243 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 02:15PM | Duration 68h15 | Departure days Thu, Sat | Cheapest price $167 |
Operator Greyhound | Departure Time 06:45PM | Arrival Time 02:15PM | Duration 67h30 | Departure days Mon, Sun | Cheapest price $203 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 07:25PM | Duration 70h10 | Departure days Mon, Sat | Cheapest price $162 |
Operator Greyhound | Departure Time 10:15PM | Arrival Time 02:05AM | Duration 75h50 | Departure days Fri | Cheapest price $143 |
The table below shows live departures for Orlando, FL to San Francisco, CA buses for tomorrow, Wednesday, July 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:05 AM Orlando, FL | 66h20 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
![]() | 2:05 AM Orlando, FL | 66h20 | 8:25 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Orlando, FL to San Francisco, CA run on average 6 times per day, taking around 67h 31m. Cheap bus tickets for this journey start at $143 (€118) if you book in advance.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 2437 miles (3922 km) distance in 66h 20m.
Distance 2437 miles (3922 km) |
Average bus duration 67h 31m |
Cheapest ticket price $143 (€118) |
Buses per day 6 |
Fastest bus 66h 20m |
First bus 6:30 AM |
Last bus 11:25 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 28 days |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Orlando, FL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Orlando, FL to San Francisco, CA buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Orlando, FL and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need