- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Bustang | Departure Time 04:35PM | Arrival Time 01:30PM | Duration 68h55 | Departure days Tue, Wed, Thu, Fri | Cheapest price €362 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Colorado Springs, CO to Florence, SC and enjoy the approximately 1422 miles (2290 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 05:45, the last at 21:35.
Distance 1422 miles (2290 km) |
First bus 5:45 AM |
Last bus 9:35 PM |
High Season Jan - Mar |
Low Season Jan - Mar |
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
Find answers to the most common questions about traveling from Colorado Springs, CO to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Colorado Springs, CO to Florence, SC buses use the Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride) to Florence, S Irby St (Greyhound Bus Stop) station pair, with some services arriving at Florence, W Lucas St (TA Gas Station). Use this guide to compare Colorado Springs, CO and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride) is 2 km from Colorado Springs city centre. Public transport options include:
Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride). ATMs are available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride).
Ticket office support is available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride).
Available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride): Parking, Taxis, WC.
Accessibility facilities are available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride): Accessible paths and ramps are available.
Florence, S Irby St (Greyhound Bus Stop) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Florence, S Irby St (Greyhound Bus Stop). ATMs are available at Florence, S Irby St (Greyhound Bus Stop).
Ticket office support is available at Florence, S Irby St (Greyhound Bus Stop).
Available at Florence, S Irby St (Greyhound Bus Stop): Parking, Taxis, WC.
Accessibility facilities are available at Florence, S Irby St (Greyhound Bus Stop): Bus stop accessible for disabled persons.
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food and snacks available at the gas station.
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
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