- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
The best way to find a cheap bus ticket from Colorado Springs, CO to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Colorado Springs, CO to Florence, SC will cost around €362 if you buy it on the day, but the cheapest tickets can be found for only €362.
It's difficult to get from Colorado Springs, CO to Florence, SC without transferring at least 3 times.

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Take a bus from Colorado Springs, CO to Florence, SC and enjoy the approximately 1422 miles (2290 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 05:45, the last at 21:35.
Distance 1422 miles (2290 km) |
First bus 5:45 AM |
Last bus 9:35 PM |
High Season Jan - Mar |
Low Season Jan - Mar |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Colorado Springs, CO to Florence, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Bustang | Departure Time 04:35PM | Arrival Time 01:30PM | Duration 68h55 | Departure days Tue, Wed, Thu, Fri | Cheapest price €362 |
The table below shows live departures for Colorado Springs, CO to Florence, SC buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:35 PM Colorado Springs, CO | 68h55 | 1:30 PM Florence, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Florence, SC.
Find answers to the most common questions about traveling from Colorado Springs, CO to Florence, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Colorado Springs, CO to Florence, SC buses use the Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride) to Florence, W Lucas St (TA Gas Station) station pair. Use this guide to compare Colorado Springs, CO and Florence, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride) is 2 km from Colorado Springs city centre. Public transport options include:
Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride). ATMs are available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride).
Ticket office support is available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride).
Available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride): Parking, Taxis, WC.
Accessibility facilities are available at Colorado Springs, S Tejon St / Ronald Reagan Hwy (Tejon Park-n-Ride): Accessible paths and ramps are available.
Florence, W Lucas St (TA Gas Station) is 6 km from Florence city centre. Public transport options include:
Florence, W Lucas St (TA Gas Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food and snacks available at the gas station.
Wi-Fi is available at Florence, W Lucas St (TA Gas Station). ATMs are available at Florence, W Lucas St (TA Gas Station).
Ticket office support is available at Florence, W Lucas St (TA Gas Station).
Available at Florence, W Lucas St (TA Gas Station): Parking, Taxis, WC.
Accessibility facilities are available at Florence, W Lucas St (TA Gas Station): Basic accessibility features available.
Check bus stations information for Colorado Springs, CO and Florence, SC, including where buses depart and arrive on this route.
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