Jacksonville, FL to Florence, SC train with Amtrak

Wed, Nov 04
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Amtrak
Regionale
Deutsche Bahn
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Frecciarossa
2,000+ travel companies
Amtrak
Regionale
Deutsche Bahn
iryo
Frecciarossa
2,000+ travel companies
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Journey information

Overview: Train from Jacksonville, FL to Florence, SC

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Trains from Jacksonville, FL to Florence, SC run on average 2 times per day, taking around 5h 53m. Cheap train tickets for this journey start at €69 but you can travel from only €39 by bus.

There are 1 trains per day. The earliest train runs at 03:18, the last at 22:33. The fastest train covers the 288 miles (465 km) distance in 5h 34m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €39
Distance
288 miles (465 km)
Average train duration
5h 53m
Cheapest ticket price
€69
Trains per day
2
Direct trains
1
Fastest train
5h 34m
First train
3:18 AM
Last train
10:33 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jul - Sep
Low Season
Apr - Jun
Busiest Day
Thu
Least Busy Day
Thu
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €39

Frequently asked questions about your Jacksonville, FL to Florence, SC trip

Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Jacksonville, FL to Florence, SC.

Train ticket prices from Jacksonville, FL to Florence, SC can vary. The cheapest ticket starts at €69, while the average price is around €80.
The train from Jacksonville, FL to Florence, SC takes 5h 34m and runs 2 per day.
The distance by train from Jacksonville, FL to Florence, SC is 288 miles (465 km).
The first train from Jacksonville, FL to Florence, SC leaves at 3:18 AM.
The last train from Jacksonville, FL to Florence, SC leaves at 10:33 PM.
Yes, there is a direct train from Jacksonville, FL to Florence, SC. This service operates 1 times per day, provided by Amtrak.

Train companies: Amtrak from Jacksonville, FL to Florence, SC trainsAmtrak trains will get you between Jacksonville, FL and Florence, SC from €39. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Amtrak Duration
5h 34m
Cheapest Amtrak Price
€69
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

Companies, tickets, and onboard amenities between Jacksonville, FL and Florence, SC

Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.

Yes, there is a high-speed train from Jacksonville, FL to Florence, SC.
Yes, there is a night train from Jacksonville, FL to Florence, SC.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.

Complete guide to Florence, SC

Things to do in Florence, SC

Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.

  • Must visit

Uffizi Gallery

Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.

  • Must visit

Galleria dell'Accademia

Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.

  • Recommended

Museo dell'Opera del Duomo

Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.

$ US Dollar

Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.

Average meal costs

Budget
$8-12 for fast food or casual takeout.
Mid-range
$15-25 per person for a casual sit-down meal.
Fine dining
$35+ per person for upscale restaurants.
Coffee
$3-5 for regular coffee or latte.

Tipping culture

Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.

Plan your visit to Florence, SC

Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Florence, SC.

The train journey from Jacksonville, FL to Florence, SC offers a blend of urban and rural landscapes, with views of quaint towns, lush greenery, and stretches of Southern countryside, though it may not be considered especially scenic compared to more renowned scenic routes.
Popular day trips by train from Florence, SC include Charleston, SC, Kingstree, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

FAQs: Trains from Jacksonville, FL to Florence, SC

Find answers to the most common questions about traveling from Jacksonville, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Yes, you can take the train from Jacksonville, FL to Florence, SC.

popular train stations

Popular train stations from Jacksonville, FL to Florence, SC

Most Jacksonville, FL to Florence, SC trains use the Jacksonville Station to Florence Station station pair. Use this guide to compare Jacksonville, FL and Florence, SC train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Jacksonville
Arrival train stations in Florence

Which Jacksonville, FL station do trains to Florence, SC leave from?

Trains from Jacksonville, FL to Florence, SC leave from Jacksonville Station. The station is 4 miles (8 km) from Jacksonville, FL city centre at 3570 Clifford Lane, Jacksonville, FL 32209, USA.
Jacksonville Station3570 Clifford Lane, Jacksonville, FL 32209, USA+1 800-872-7245ParkingTaxisAccessibilityWCTicket OfficeInformation DeskLuggage Carts
City-centre transport

Getting to Jacksonville Station from Jacksonville city centre

Jacksonville Station is 7 km from Jacksonville city centre. Public transport options include:

BusSeveral lines available

Jacksonville Station train station facilities and services

Jacksonville Station has practical services for this route, including Parking, Taxis, Accessibility, WC, Ticket Office, Information Desk, and Luggage Carts.

Tickets and information

Ticket office support is available at Jacksonville Station. Information desks are located in the main hall.

Parking, taxis and toilets

Available at Jacksonville Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Jacksonville Station: Ramps, restrooms.

Train stations for Jacksonville, FL to Florence, SC

Check train stations information for Jacksonville, FL and Florence, SC, including where trains depart and arrive on this route.

The train station in Jacksonville, FL that goes to Florence, SC is Jacksonville Station, which connects to Florence Station.

More options for your journey from Jacksonville, FL to Florence, SC

Here are some other resources that might have the information you need

Most popular trains to and from Florence, SC and Jacksonville, FL

HomeTrainsTrains in USATrain Times to Florence, SCJacksonville, FL to Florence, SC train

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