- Must visit
Uffizi Galleries
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
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Travel Information
Compare bus and train for Jacksonville, FL to Florence, SC
Omio recommends booking the train as it is the most popular option from Jacksonville, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a bus which can get you there in 5h 30m. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $67.
Distance: 288 miles (465 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$91 Average price | $69 Average price Cheapest | $62 Average price (fuel + tolls) |
6h 34m Average total duration 6h 4m Onboard + 30m Additional time* | 6h 0m Average total duration Fastest 5h 30m Onboard + 30m Additional time* | 4h 25m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Jacksonville, FL to Florence, SC is a bus with an average price of $69 (€57).
This is compared to other travel options from Jacksonville, FL to Florence, SC:
A bus is $22 (€18) less than a train for this route with tickets for a train from Jacksonville, FL to Florence, SC costing on average $91 (€75).
The fastest way to travel from Jacksonville, FL to Florence, SC is by bus with an average journey time of 5h 30m.
Other travel options to Florence, SC take longer:
Train takes on average 6h 4m.
It's helpful to compare your options as there are 2 ways to travel between Jacksonville, FL and Florence, SC including taking a bus and train.
We recommend using the train as it is the most popular way to get from Jacksonville, FL to Florence, SC among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $91 (€75) compared to roughly $62 (€51) in fuel and tolls — a saving of about $-29.18 (€-23.88). The journey takes 6h 4m versus 4h 25m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare prices and tickets Jacksonville, FL to Florence, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Jacksonville, FL to Florence, SC
USAUSA
Trains from Jacksonville, FL to Florence, SC run on average 2 times per day, taking around 6h 4m. Cheap train tickets for this journey start at $67 (€55) but you can travel from only $62 (€51) by bus.
There are 1 trains per day. The earliest train runs at 03:18, the last at 22:33. The fastest train covers the 288 miles (465 km) distance in 6h 11m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $62 (€51)
Distance 288 miles (465 km) |
Average train duration 6h 4m |
Cheapest ticket price $67 (€55) |
Trains per day 2 |
Direct trains 1 |
Fastest train 6h 11m |
First train 3:18 AM |
Last train 10:33 PM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $62 (€51)
Train companies: Amtrak from Jacksonville, FL to Florence, SC trainsAmtrak trains will get you between Jacksonville, FL and Florence, SC from $62 (€51). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
6h 11m
Cheapest Price
$67 (€55)
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Florence
Things to do in Florence
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
- Must visit
Accademia Gallery
Best known for Michelangelo’s David, this compact museum is one of Florence’s essential stops. Advance booking is commonly recommended because queues can be long.
- Recommended
Palazzo Pitti
Large palace museum complex with royal apartments, paintings, and design collections. Worth visiting for its scale, courtly interiors, and links to Medici history.
- Must visit
Piazza del Duomo
The monumental heart of Florence, surrounded by the cathedral, dome, baptistery, and bell tower. Essential for first-time visitors and classic city views.
- Must visit
Piazza della Signoria
Historic square lined with civic architecture and open-air sculptures. One of Florence’s liveliest public spaces and a key stop on any walking route.
- Must visit
Piazzale Michelangelo
The city’s most famous viewpoint, especially popular at sunset for sweeping skyline photos. A social media favorite and classic Florence panorama.
- Gluten-free
Pulled Pork Barbecue
Slow-smoked pork shoulder, usually chopped or pulled and served with a tangy Southern barbecue sauce. It is a staple across the Carolinas and common in Florence-area smokehouses.
Fried Catfish
Cornmeal-coated catfish fillets fried until crisp, often served with hush puppies and slaw. This is a classic Pee Dee and broader South Carolina comfort dish.
- Gluten-free
Shrimp And Grits
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a light sauce. A defining Lowcountry and South Carolina dish regularly found in Florence.
Wholly Smokin' Downtown
Established downtown barbecue spot specializing in smoked meats, Southern sides, and a casual local atmosphere.
Victors
Upscale, long-running Florence restaurant known for steaks, seafood, and polished Southern-American dining in an elegant setting.
Tubb's Shrimp & Fish Co.
Well-known casual seafood restaurant recognized for fried seafood platters, shrimp, fish, and regional comfort fare.
United States Dollar
Costs are moderate for the U.S. Budget eats are easy to find, while hotels and fine dining can raise daily costs.
Average meal costs
- Budget
- USD 8-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 50-100+ per person before drinks and tip.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff USD 2-5 for helpful service.
FAQs: Trains from Jacksonville, FL to Florence, SC
Find answers to the most common questions about traveling from Jacksonville, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
Train ticket prices from Jacksonville, FL to Florence, SC can vary. The cheapest ticket starts at $67 (€55), while the average price is around $91 (€75).
The train from Jacksonville, FL to Florence, SC takes 6h 11m and runs 2 per day.
The distance by train from Jacksonville, FL to Florence, SC is 288 miles (465 km).
The first train from Jacksonville, FL to Florence, SC leaves at 3:18 AM.
The last train from Jacksonville, FL to Florence, SC leaves at 10:33 PM.
There is no high speed train available from Jacksonville, FL to Florence, SC.
There is no direct train service currently available from Jacksonville, FL to Florence, SC.
Unfortunately, there is no night train available from Jacksonville, FL to Florence, SC.
The train station in Jacksonville, FL that goes to Florence, SC is Jacksonville station, Jacksonville, FL, which connects to Florence Station, Florence, SC.
The cheapest way to get from Jacksonville, FL to Florence, SC is by bus, with a cost of around $62 (€51).
The train journey from Jacksonville, FL to Florence, SC offers a blend of urban and rural landscapes, with views of quaint towns, lush greenery, and stretches of Southern countryside, though it may not be considered especially scenic compared to more renowned scenic routes.
A day trip from Jacksonville, FL to Florence, SC is not feasible as the journey takes 6h 11m. However, there are 2 train trips per day available for this route.
To fully explore Florence, SC, two to three days are recommended. This allows time to visit local attractions such as the Florence County Museum, War Between the States Museum, and enjoy the local dining and shopping experiences.
Yes, you can take the train from Jacksonville, FL to Florence, SC.
Since neither Jacksonville, FL nor Florence, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from Florence, SC include Charleston, SC, Kingstree, SC.
We recommend using the train as it is the most popular way to get from Jacksonville, FL to Florence, SC among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Jacksonville, FL to Florence, SC
Jacksonville
Florence
The major train station for departures in Jacksonville is Jacksonville Station. Find all the information you need to know about services, amenities and connections at Jacksonville Station for your trip from Jacksonville to Florence.
Jacksonville Station
Amenities at train station
ParkingTaxisAccessibilityWCTicket OfficeInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 11:00 PM Monday - Sunday
Distance to city center
7 km
Number of platforms
1Parking
- Parking is available at the station
Taxis
- Outside the main entrance
Accessibility
- Ramps, restrooms
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- The station has an enclosed waiting area.
Public transit options for Jacksonville Station
- Bus: Several lines available
The major train station for arrivals in Florence is Florence Station. Find all the information you need to know about services, amenities and connections at Florence Station for your journey to Florence from Jacksonville.
Florence Station
Amenities at train station
LockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 11:00 PM Monday - Sunday
Number of platforms
2Parking
- Parking is available at the station
Taxis
- Outside the main entrance
Accessibility
- Elevators, ramps
Hotel
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- The station has an enclosed waiting area.
Public transit options for Florence Station
- Bus: Greyhound services available nearby
More options for your journey from Jacksonville, FL to Florence, SC
Here are some other resources that might have the information you need
Most popular trains to and from Florence, SC and Jacksonville, FL
Most popular train connections to Florence, SC
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