Travel Information
Compare bus and train for Jacksonville, FL to Florence, SC
Omio recommends booking the train as it is the most popular option from Jacksonville, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $56. For those with little time consider booking a bus which can get you there in 5h 30m. The ticket price range depends on the travel mode: a bus costs an average of $56, and a train costs an average of $69.
Distance: 288 miles (465 km)
Compare train with
Most popular Train | Bus |
|---|---|
$93 Average price | $74 Average price Cheapest |
6h 30m Average total duration 6h 0m Onboard + 30m Additional time* | 6h 0m Average total duration Fastest 5h 30m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
This is compared to other travel options from Jacksonville, FL to Florence, SC:
A bus is $19 (€15) less than a train for this route with tickets for a train from Jacksonville, FL to Florence, SC costing on average $93 (€74).
Other travel options to Florence, SC take longer:
Train takes on average 6h 0m.
Compare prices and tickets Jacksonville, FL to Florence, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Jacksonville, FL to Florence, SC
Trains from Jacksonville, FL to Florence, SC run on average 2 times per day, taking around 6h 0m. Cheap train tickets for this journey start at $69 (€55) but you can travel from only $56 (€45) by bus.
There are 1 trains per day. The earliest train runs at 03:18, the last at 22:33. The fastest train covers the 288 miles (465 km) distance in 6h 11m.
Distance 288 miles (465 km) |
Average train duration 6h 0m |
Cheapest ticket price $69 (€55) |
Trains per day 2 |
Direct trains 1 |
Fastest train 6h 11m |
First train 3:18 AM |
Last train 10:33 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Train companies: Amtrak from Jacksonville, FL to Florence, SC trainsAmtrak trains will get you between Jacksonville, FL and Florence, SC from $56 (€45). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Jacksonville, FL to Florence, SC
Find answers to the most common questions about traveling from Jacksonville, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Jacksonville, FL to Florence, SC
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps, restrooms.
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Several lines available
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
More options for your journey from Jacksonville, FL to Florence, SC
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