- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price on Sep 20
€242
Average ticket price on Sep 20
€271
Fastest journey on Sep 20
2 d 18 h
Average journey duration on Sep 20
2 d 20 h 20 m
Buses on Sep 20
2
Distance
3814 km
The best way to find a cheap bus ticket from Jacksonville, FL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to San Francisco, CA will cost around €271 if you buy it on the day, but the cheapest tickets can be found for only €242.
On Sun, Sep 20, we found 2 buses from Jacksonville, FL to San Francisco, CA, including 2 direct services.
On Sun, Sep 20 the direct buses cover the 3814 km distance in an average of 2 d 20 h 20 m but if you time it right, some buses will get you there in just 2 d 18 h .
On Sun, Sep 20 the slowest buses will take 2 d 22 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Jacksonville, FL to San Francisco, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €332 For those with little time, consider booking a flight, which has an average total journey time of 9h 32m. Average ticket prices depend on the travel mode: a bus costs an average of €332, while a flight costs an average of €677.
Distance: 2369 miles (3814 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
€332 Average price Cheapest | €677 Average price | €454 Average price (fuel + tolls) | |
63h 2m Average total duration 62h 32m Onboard + 30m Additional time* | 9h 32m Average total duration Fastest 7h 32m Onboard + 2h 0m Additional time* | 40h 9m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Jacksonville, FL to San Francisco, CA:
A bus is €345 less than a flight for this route with tickets for a flight from Jacksonville, FL to San Francisco, CA costing on average €677.
Other travel options to San Francisco, CA take longer:
Bus takes on average 62h 32m.
Tickets start at around €332 compared to roughly €454 in fuel and tolls — a saving of about €123. The journey takes 62h 32m versus 40h 9m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:25AM | Arrival Time 12:35AM | Duration 71h10 | Departure days Fri, Sat, Sun | Cheapest price €206 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 08:25PM | Duration 66h00 | Departure days Sat, Sun | Cheapest price €242 |
The table below shows live departures for Jacksonville, FL to San Francisco, CA buses for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:25 AM Jacksonville, FL | 66h00 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
![]() | 2:25 AM Jacksonville, FL | 70h40 | 1:05 AM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Jacksonville, FL to San Francisco, CA run on average 3 times per day, taking around 62h 32m. Cheap bus tickets for this journey start at €226 if you book in advance.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 2369 miles (3814 km) distance in 61h 20m.
Distance 2369 miles (3814 km) |
Average bus duration 62h 32m |
Cheapest ticket price €226 |
Buses per day 3 |
Fastest bus 61h 20m |
First bus 6:30 AM |
Last bus 11:25 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Jacksonville, FL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Jacksonville, FL to San Francisco, CA buses use the Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Jacksonville, FL and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 km from Jacksonville city centre. Public transport options include:
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. ATMs are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Ticket office support is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Parking, Taxis, WC.
Accessibility facilities are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Wheelchair accessible entrances.
San Francisco, Transit Center Bay 29 is 2 km from San Francisco city centre. Public transport options include:
San Francisco, Transit Center Bay 29 has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Francisco, Transit Center Bay 29. ATMs are available at San Francisco, Transit Center Bay 29.
Ticket office support is available at San Francisco, Transit Center Bay 29.
Available at San Francisco, Transit Center Bay 29: Parking, Taxis, WC.
Accessibility facilities are available at San Francisco, Transit Center Bay 29: Wheelchair accessible areas present.
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