- Must visit
San Francisco Museum of Modern Art
Major contemporary art museum with an outstanding modern and contemporary collection, large-scale installations, and strong photography holdings.
Cheapest price
$296
Average price
$331
Fastest journey
2 d 18 h
Average duration
2 d 20 h 20 m
Buses per day
2
Distance
3814 km
The best way to find a cheap bus ticket from Jacksonville, FL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to San Francisco, CA will cost around $331 if you buy it on the day, but the cheapest tickets can be found for only $296.
Of the 2 buses that leave Jacksonville, FL for San Francisco, CA on Sun, Jun 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 3814 km distance in an average of 2 d 20 h 20 m but if you time it right, some buses will get you there in just 2 d 18 h .
On Sun, Jun 21 the slowest buses will take 2 d 22 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Jacksonville, FL to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $159. For those with little time consider booking a flight which can get you there in 9h 57m. The ticket price range depends on the travel mode: a bus costs an average of $159, and a train costs an average of $582.
Distance: 2369 miles (3814 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$288 Average price Cheapest | $412 Average price | $1109 Average price | $548 Average price (fuel + tolls) |
68h 58m Average total duration 68h 28m Onboard + 30m Additional time* | 12h 57m Average total duration Fastest 9h 57m Onboard + 3h 0m Additional time* | 95h 51m Average total duration 95h 21m Onboard + 30m Additional time* | 40h 9m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Jacksonville, FL to San Francisco, CA:
A bus is $124 (€102) less than a flight for this route with tickets for a flight from Jacksonville, FL to San Francisco, CA costing on average $412 (€337).
A bus is $821 (€672) less than a train for this route with tickets for a train from Jacksonville, FL to San Francisco, CA costing on average $1109 (€907).
Other travel options to San Francisco, CA take longer:
Bus takes on average 68h 28m.
Train takes on average 95h 21m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:25AM | Arrival Time 07:25PM | Duration 66h00 | Departure days Fri, Sun | Cheapest price $282 |
Operator Greyhound | Departure Time 02:25AM | Arrival Time 01:05AM | Duration 70h40 | Departure days Sun | Cheapest price $296 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 07:10AM | Duration 65h40 | Departure days Fri | Cheapest price $225 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 12:35PM | Duration 66h10 | Departure days Fri | Cheapest price $186 |
The table below shows live departures for Jacksonville, FL to San Francisco, CA buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · + FlixBus | 9:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 71h25 | 5:50 PM San Francisco, Townsend Street / 5th Street, CA | 3 transfers | |
FlixBus+ · · | 9:25 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 66h10 | 12:35 PM San Francisco, Transit Center Bay 29 | 5 transfers | |
| Saturday, June 20 | |||||
![]() | 1:25 AM Jacksonville, FL | 66h00 | 7:25 PM San Francisco, CA | 0 transfersDirect | |
![]() | 2:25 AM Jacksonville, FL | 70h40 | 1:05 AM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Jacksonville, FL to San Francisco, CA run on average 5 times per day, taking around 68h 28m. Cheap bus tickets for this journey start at $159 (€130) if you book in advance.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 2369 miles (3814 km) distance in 66h 0m.
Distance 2369 miles (3814 km) |
Average bus duration 68h 28m |
Cheapest ticket price $159 (€130) |
Buses per day 5 |
Fastest bus 66h 0m |
First bus 6:30 AM |
Last bus 11:25 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Major contemporary art museum with an outstanding modern and contemporary collection, large-scale installations, and strong photography holdings.
Interactive science and art museum on the Embarcadero, especially popular for hands-on exhibits and bayfront setting.
Fine arts museum in Golden Gate Park known for American art, textiles, rotating exhibitions, and its panoramic observation tower.
The famously crooked block lined with flowers and city views, one of San Francisco's most photographed streets.
Massive urban park with gardens, lakes, museums, and broad walking space that rewards both short visits and full-day exploration.
High viewpoint with sweeping panoramic views over the city and bay, especially popular at sunset and on clear mornings.
A tomato-based seafood stew created by Italian fishermen in San Francisco, usually filled with crab, clams, mussels, shrimp, and fish. It is one of the city’s signature dishes.
San Francisco sourdough is famous for its tangy flavor and chewy crust, shaped by the city’s historic baking culture and local wild yeast tradition.
A large burrito associated with the Mission District, typically packed with rice, beans, meat, salsa, and extras. It is a defining San Francisco street food.
North Beach favorite specializing in cioppino and classic seafood in a lively, casual setting.
Iconic Mission District taqueria celebrated for Mission-style burritos and tacos with a no-frills local vibe.
Classic waterfront cafe famous for Irish Coffee, hearty breakfasts, and historic cable-car-adjacent charm.
One of the priciest U.S. cities. Hotels, dining, parking, and taxes add up quickly, though transit and casual food can help control costs.
Restaurants: 18-22% is standard before or after tax depending on the screen shown. Bars: USD 1-2 per drink. Taxis/rideshare: 10-15% or round up. Hotel staff: USD 2-5 for porters, a few USD nightly for housekeeping.
Find answers to the most common questions about traveling from Jacksonville, FL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Jacksonville, FL to San Francisco, CA buses use the Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Jacksonville, FL and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need