- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
The best way to find a cheap flight ticket from Greenville, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Orlando, FL will cost around €226 if you buy it on the day, but the cheapest tickets can be found for only €102.
On Tue, Nov 03, we found 2 flights from Greenville, SC to Orlando, FL, including 2 direct services.
On Tue, Nov 03 the direct flights cover the 709 km distance in an average of 7 h 24 m but if you time it right, some flights will get you there in just 5 h 44 m .
On Tue, Nov 03 the longest flights will take 9 h 4 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Flights from Greenville, SC to Orlando, FL depart on average 14 times per day, taking around 3h 23m. Cheap flight tickets for this journey start at €89 but you can travel from only €56 by bus.
There are 1 flights per day. The earliest flight runs at 05:00, the last at 22:10. The fastest flight covers the 440 miles (709 km) distance in 1h 21m. May is the cheapest month to fly.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Greenville, SC to Orlando, FL.
Flights from Greenville, SC to Orlando, FL with American Airlines, Breeze Airways, and Allegiant Air. Flights with a stop available on this route with American Airlines and psa airlines. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Orlando, FL.
Find answers to the most common questions about traveling from Greenville, SC to Orlando, FL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Orlando, FL flights use the Greenville-Spartanburg International Airport to Orlando International Airport airport pair, with some services landing at Orlando Sanford International Airport. Use this guide to compare Greenville, SC and Orlando, FL airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Greenville-Spartanburg International Airport is 5 km from Greenville city centre. Public transport options include:
Greenville-Spartanburg International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several dining options are available in the terminal.
Free Wi-Fi available throughout the terminal. ATMs are aTMs available near baggage claim.
Ticket office support is available at Greenville-Spartanburg International Airport.
Available at Greenville-Spartanburg International Airport: Parking, Taxis, WC.
Accessibility facilities are available at Greenville-Spartanburg International Airport: Elevators and ramps available for accessibility.
Orlando International Airport is 13 km from Orlando city centre. Public transport options include:
Orlando International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in all terminals, including fast food and sit-down options like McDold's and Outback Steakhouse
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport.
Lost and found is available at the station.
Available at Orlando International Airport: Parking, Taxis, WC.
Available at Orlando International Airport: Car Rental.
Accessibility facilities are available at Orlando International Airport: Ramps, assistance.
Nearby hotels include Hyatt Regency located within the airport..
Orlando Sanford International Airport is 4 km from Orlando city centre. Public transport options include:
Orlando Sanford International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants available; located in the terminal, options include fast food and sit-down dining like Cheeburger Cheeburger and Cinbon.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Orlando Sanford International Airport: Parking, Taxis, WC.
Available at Orlando Sanford International Airport: Car Rental.
Accessibility facilities are available at Orlando Sanford International Airport: Elevators, ramps.
Nearby hotels include Hotels nearby, within walking distance, Best Western Plus Sanford Airport/Lake Mary Hotel..
See which airports are used for flights between Greenville, SC and Orlando, FL, including airport details.