- Must visit
Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Flights from Greenville, SC to Orlando, FL depart on average 10 times per day, taking around 3h 22m. Cheap flight tickets for this journey start at €88 but you can travel from only €64 by bus.
There are 1 flights per day. The earliest flight runs at 05:00, the last at 22:10. The fastest flight covers the 440 miles (709 km) distance in 1h 21m. May is the cheapest month to fly.
Distance 440 miles (709 km) |
Average flight duration 3h 22m |
Cheapest ticket price €88 |
Flights per day 10 |
Direct flights 1 |
Fastest flight 1h 21m |
First flight 5:00 AM |
Last flight 10:10 PM |
Cheapest Month May |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Cheapest price on Sep 19
€163
Average ticket price on Sep 19
€163
Fastest journey on Sep 19
6 h 2 m
Average journey duration on Sep 19
6 h 2 m
Flights on Sep 19
1
Distance
709 km
The best way to find a cheap flight ticket from Greenville, SC to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Orlando, FL will cost around €163 if you buy it on the day, but the cheapest tickets can be found for only €163.
On Sat, Sep 19, we found 1 flights from Greenville, SC to Orlando, FL, including 1 direct services.
On Sat, Sep 19 the direct flights cover the 709 km distance in an average of 6 h 2 m but if you time it right, some flights will get you there in just 6 h 2 m .
On Sat, Sep 19 the longest flights will take 6 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Greenville, SC to Orlando, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €91 For those with little time, consider booking a flight, which has an average total journey time of 5h 22m. Average ticket prices depend on the travel mode: a bus costs an average of €91, while a train costs an average of €473.
Distance: 440 miles (709 km)
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
€407 Average price | €91 Average price Cheapest | €473 Average price | €85 Average price (fuel + tolls) |
5h 22m Average total duration Fastest 3h 22m Onboard + 2h 0m Additional time* | 12h 55m Average total duration 12h 25m Onboard + 30m Additional time* | 27h 36m Average total duration 27h 6m Onboard + 30m Additional time* | 7h 36m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Orlando, FL:
A bus is €315 less than a flight for this route with tickets for a flight from Greenville, SC to Orlando, FL costing on average €407.
A bus is €382 less than a train for this route with tickets for a train from Greenville, SC to Orlando, FL costing on average €473.
Other travel options to Orlando, FL take longer:
Bus takes on average 12h 25m.
Train takes on average 27h 6m.
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
Find answers to the most common questions about traveling from Greenville, SC to Orlando, FL by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Orlando, FL flights use the Greenville-Spartanburg International Airport to Orlando International Airport airport pair, with some services landing at Orlando Sanford International Airport. Use this guide to compare Greenville, SC and Orlando, FL airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Greenville-Spartanburg International Airport is 5 km from Greenville city centre. Public transport options include:
Greenville-Spartanburg International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several dining options are available in the terminal.
Free Wi-Fi available throughout the terminal. ATMs are aTMs available near baggage claim.
Ticket office support is available at Greenville-Spartanburg International Airport.
Available at Greenville-Spartanburg International Airport: Parking, Taxis, WC.
Accessibility facilities are available at Greenville-Spartanburg International Airport: Elevators and ramps available for accessibility.
Orlando International Airport is 13 km from Orlando city centre. Public transport options include:
Orlando International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in all terminals, including fast food and sit-down options like McDold's and Outback Steakhouse
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport.
Lost and found is available at the station.
Available at Orlando International Airport: Parking, Taxis, WC.
Available at Orlando International Airport: Car Rental.
Accessibility facilities are available at Orlando International Airport: Ramps, assistance.
Nearby hotels include Hyatt Regency located within the airport..
Orlando Sanford International Airport is 4 km from Orlando city centre. Public transport options include:
Orlando Sanford International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants available; located in the terminal, options include fast food and sit-down dining like Cheeburger Cheeburger and Cinbon.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Orlando Sanford International Airport: Parking, Taxis, WC.
Available at Orlando Sanford International Airport: Car Rental.
Accessibility facilities are available at Orlando Sanford International Airport: Elevators, ramps.
Nearby hotels include Hotels nearby, within walking distance, Best Western Plus Sanford Airport/Lake Mary Hotel..
Here are some other resources that might have the information you need